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Eva Hadadi
Eva Hadadi
Myeloid Cell Immunology Lab, VIB Center for Inflammation Research, Brussels, Belgium
Lab of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgium
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Lab of Cellular and Molecular Immunology, Vrije Universiteit Brussel, Brussels, Belgium
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Hervé Acloque
Hervé Acloque
INSERM U935, University Paris Saclay, Villejuif, Ile-de-France, France
Université Paris-Saclay, INRAE, AgroParisTech, GABI, Jouy-en-Josas, Ile-de-France, France
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Université Paris-Saclay, INRAE, AgroParisTech, GABI, Jouy-en-Josas, Ile-de-France, France
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be hallmarks of cancer (31) are directly regulated by the circadian clock. Specific biological processes under circadian regulation are specified in red. Circadian rhythm disruption and endocrine related cancers The adaptation of animal
Arun Mouli Kolinjivadi
Arun Mouli Kolinjivadi
Lee Kong Chian School of Medicine, Nanyang Technological University Singapore, Singapore, Singapore
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Siao Ting Chong
Siao Ting Chong
Lee Kong Chian School of Medicine, Nanyang Technological University Singapore, Singapore, Singapore
Cancer Genetics Service, Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore
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Cancer Genetics Service, Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore
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Joanne Ngeow
Joanne Ngeow
Lee Kong Chian School of Medicine, Nanyang Technological University Singapore, Singapore, Singapore
Cancer Genetics Service, Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore
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Cancer Genetics Service, Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore
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rhythm that follow a 24-h periodicity governing the essential cellular and molecular events. Several landmark studies in mammals, zebrafish, plants, fungi and cyanobacteria support the concept of biological clock or circadian rhythm impacting different
Anna Angelousi
Anna Angelousi
Endocrine Unit, 1st Department of Internal Medicine, Laiko Hospital, National and Kapodistrian University of Athens, Athens, Greece
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Eva Kassi
Eva Kassi
Endocrine Unit, 1st Department of Internal Medicine, Laiko Hospital, National and Kapodistrian University of Athens, Athens, Greece
Department of Biological Chemistry, Medical School, National and Kapodistrian University of Athens, Athens, Greece
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Department of Biological Chemistry, Medical School, National and Kapodistrian University of Athens, Athens, Greece
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Narjes Ansari-Nasiri
Narjes Ansari-Nasiri
Department of Biological Chemistry, Medical School, National and Kapodistrian University of Athens, Athens, Greece
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Harpal Randeva
Harpal Randeva
Warwickshire Institute for the Study of Diabetes, Endocrinology and Metabolism (WISDEM), University Hospitals Coventry and Warwickshire NHS Trust, Coventry, UK
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Gregory Kaltsas
Gregory Kaltsas
Endocrine Unit, 1st Department of Propaedeutic Medicine, Laiko University Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece
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George Chrousos
George Chrousos
First Department of Pediatrics, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece
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Introduction Circadian rhythms are biological rhythms that exhibit a periodicity close to 24 h. In mammals, these rhythms are generated by a master biological clock, located centrally in the suprachiasmatic nucleus (SCN) of the hypothalamus
Thérèse Truong
Thérèse Truong
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Environmental Epidemiology of Cancer, Villejuif, France
Université Paris-Sud UMRS 1018, Villejuif, France
Biostatistical Unit MRC, Cambridge, UK
School of Mathematics and Physics The University of Queensland, St Lucia, Queensland, Australia
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease Over Lifecourse, Villejuif, France
Université Paris Descartes INSERM UMR-S775 EPIGENETEC, Paris, France
Département d'informatique médicale Center Georges-François Leclerc, Dijon, France
Center Eugène Marquis Rennes, France
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Environmental Epidemiology of Cancer, Villejuif, France
Université Paris-Sud UMRS 1018, Villejuif, France
Biostatistical Unit MRC, Cambridge, UK
School of Mathematics and Physics The University of Queensland, St Lucia, Queensland, Australia
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease Over Lifecourse, Villejuif, France
Université Paris Descartes INSERM UMR-S775 EPIGENETEC, Paris, France
Département d'informatique médicale Center Georges-François Leclerc, Dijon, France
Center Eugène Marquis Rennes, France
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Université Paris-Sud UMRS 1018, Villejuif, France
Biostatistical Unit MRC, Cambridge, UK
School of Mathematics and Physics The University of Queensland, St Lucia, Queensland, Australia
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease Over Lifecourse, Villejuif, France
Université Paris Descartes INSERM UMR-S775 EPIGENETEC, Paris, France
Département d'informatique médicale Center Georges-François Leclerc, Dijon, France
Center Eugène Marquis Rennes, France
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Environmental Epidemiology of Cancer, Villejuif, France
Université Paris-Sud UMRS 1018, Villejuif, France
Biostatistical Unit MRC, Cambridge, UK
School of Mathematics and Physics The University of Queensland, St Lucia, Queensland, Australia
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease Over Lifecourse, Villejuif, France
Université Paris Descartes INSERM UMR-S775 EPIGENETEC, Paris, France
Département d'informatique médicale Center Georges-François Leclerc, Dijon, France
Center Eugène Marquis Rennes, France
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Benoît Liquet
Benoît Liquet
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Environmental Epidemiology of Cancer, Villejuif, France
Université Paris-Sud UMRS 1018, Villejuif, France
Biostatistical Unit MRC, Cambridge, UK
School of Mathematics and Physics The University of Queensland, St Lucia, Queensland, Australia
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease Over Lifecourse, Villejuif, France
Université Paris Descartes INSERM UMR-S775 EPIGENETEC, Paris, France
Département d'informatique médicale Center Georges-François Leclerc, Dijon, France
Center Eugène Marquis Rennes, France
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Environmental Epidemiology of Cancer, Villejuif, France
Université Paris-Sud UMRS 1018, Villejuif, France
Biostatistical Unit MRC, Cambridge, UK
School of Mathematics and Physics The University of Queensland, St Lucia, Queensland, Australia
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease Over Lifecourse, Villejuif, France
Université Paris Descartes INSERM UMR-S775 EPIGENETEC, Paris, France
Département d'informatique médicale Center Georges-François Leclerc, Dijon, France
Center Eugène Marquis Rennes, France
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Université Paris-Sud UMRS 1018, Villejuif, France
Biostatistical Unit MRC, Cambridge, UK
School of Mathematics and Physics The University of Queensland, St Lucia, Queensland, Australia
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease Over Lifecourse, Villejuif, France
Université Paris Descartes INSERM UMR-S775 EPIGENETEC, Paris, France
Département d'informatique médicale Center Georges-François Leclerc, Dijon, France
Center Eugène Marquis Rennes, France
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Environmental Epidemiology of Cancer, Villejuif, France
Université Paris-Sud UMRS 1018, Villejuif, France
Biostatistical Unit MRC, Cambridge, UK
School of Mathematics and Physics The University of Queensland, St Lucia, Queensland, Australia
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease Over Lifecourse, Villejuif, France
Université Paris Descartes INSERM UMR-S775 EPIGENETEC, Paris, France
Département d'informatique médicale Center Georges-François Leclerc, Dijon, France
Center Eugène Marquis Rennes, France
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Florence Menegaux
Florence Menegaux
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Environmental Epidemiology of Cancer, Villejuif, France
Université Paris-Sud UMRS 1018, Villejuif, France
Biostatistical Unit MRC, Cambridge, UK
School of Mathematics and Physics The University of Queensland, St Lucia, Queensland, Australia
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease Over Lifecourse, Villejuif, France
Université Paris Descartes INSERM UMR-S775 EPIGENETEC, Paris, France
Département d'informatique médicale Center Georges-François Leclerc, Dijon, France
Center Eugène Marquis Rennes, France
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Environmental Epidemiology of Cancer, Villejuif, France
Université Paris-Sud UMRS 1018, Villejuif, France
Biostatistical Unit MRC, Cambridge, UK
School of Mathematics and Physics The University of Queensland, St Lucia, Queensland, Australia
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease Over Lifecourse, Villejuif, France
Université Paris Descartes INSERM UMR-S775 EPIGENETEC, Paris, France
Département d'informatique médicale Center Georges-François Leclerc, Dijon, France
Center Eugène Marquis Rennes, France
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Université Paris-Sud UMRS 1018, Villejuif, France
Biostatistical Unit MRC, Cambridge, UK
School of Mathematics and Physics The University of Queensland, St Lucia, Queensland, Australia
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease Over Lifecourse, Villejuif, France
Université Paris Descartes INSERM UMR-S775 EPIGENETEC, Paris, France
Département d'informatique médicale Center Georges-François Leclerc, Dijon, France
Center Eugène Marquis Rennes, France
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Environmental Epidemiology of Cancer, Villejuif, France
Université Paris-Sud UMRS 1018, Villejuif, France
Biostatistical Unit MRC, Cambridge, UK
School of Mathematics and Physics The University of Queensland, St Lucia, Queensland, Australia
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease Over Lifecourse, Villejuif, France
Université Paris Descartes INSERM UMR-S775 EPIGENETEC, Paris, France
Département d'informatique médicale Center Georges-François Leclerc, Dijon, France
Center Eugène Marquis Rennes, France
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Sabine Plancoulaine
Sabine Plancoulaine
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Environmental Epidemiology of Cancer, Villejuif, France
Université Paris-Sud UMRS 1018, Villejuif, France
Biostatistical Unit MRC, Cambridge, UK
School of Mathematics and Physics The University of Queensland, St Lucia, Queensland, Australia
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease Over Lifecourse, Villejuif, France
Université Paris Descartes INSERM UMR-S775 EPIGENETEC, Paris, France
Département d'informatique médicale Center Georges-François Leclerc, Dijon, France
Center Eugène Marquis Rennes, France
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Environmental Epidemiology of Cancer, Villejuif, France
Université Paris-Sud UMRS 1018, Villejuif, France
Biostatistical Unit MRC, Cambridge, UK
School of Mathematics and Physics The University of Queensland, St Lucia, Queensland, Australia
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease Over Lifecourse, Villejuif, France
Université Paris Descartes INSERM UMR-S775 EPIGENETEC, Paris, France
Département d'informatique médicale Center Georges-François Leclerc, Dijon, France
Center Eugène Marquis Rennes, France
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Université Paris-Sud UMRS 1018, Villejuif, France
Biostatistical Unit MRC, Cambridge, UK
School of Mathematics and Physics The University of Queensland, St Lucia, Queensland, Australia
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease Over Lifecourse, Villejuif, France
Université Paris Descartes INSERM UMR-S775 EPIGENETEC, Paris, France
Département d'informatique médicale Center Georges-François Leclerc, Dijon, France
Center Eugène Marquis Rennes, France
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Environmental Epidemiology of Cancer, Villejuif, France
Université Paris-Sud UMRS 1018, Villejuif, France
Biostatistical Unit MRC, Cambridge, UK
School of Mathematics and Physics The University of Queensland, St Lucia, Queensland, Australia
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease Over Lifecourse, Villejuif, France
Université Paris Descartes INSERM UMR-S775 EPIGENETEC, Paris, France
Département d'informatique médicale Center Georges-François Leclerc, Dijon, France
Center Eugène Marquis Rennes, France
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Pierre Laurent-Puig
Pierre Laurent-Puig
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Environmental Epidemiology of Cancer, Villejuif, France
Université Paris-Sud UMRS 1018, Villejuif, France
Biostatistical Unit MRC, Cambridge, UK
School of Mathematics and Physics The University of Queensland, St Lucia, Queensland, Australia
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease Over Lifecourse, Villejuif, France
Université Paris Descartes INSERM UMR-S775 EPIGENETEC, Paris, France
Département d'informatique médicale Center Georges-François Leclerc, Dijon, France
Center Eugène Marquis Rennes, France
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Université Paris-Sud UMRS 1018, Villejuif, France
Biostatistical Unit MRC, Cambridge, UK
School of Mathematics and Physics The University of Queensland, St Lucia, Queensland, Australia
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease Over Lifecourse, Villejuif, France
Université Paris Descartes INSERM UMR-S775 EPIGENETEC, Paris, France
Département d'informatique médicale Center Georges-François Leclerc, Dijon, France
Center Eugène Marquis Rennes, France
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Claire Mulot
Claire Mulot
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Environmental Epidemiology of Cancer, Villejuif, France
Université Paris-Sud UMRS 1018, Villejuif, France
Biostatistical Unit MRC, Cambridge, UK
School of Mathematics and Physics The University of Queensland, St Lucia, Queensland, Australia
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease Over Lifecourse, Villejuif, France
Université Paris Descartes INSERM UMR-S775 EPIGENETEC, Paris, France
Département d'informatique médicale Center Georges-François Leclerc, Dijon, France
Center Eugène Marquis Rennes, France
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Université Paris-Sud UMRS 1018, Villejuif, France
Biostatistical Unit MRC, Cambridge, UK
School of Mathematics and Physics The University of Queensland, St Lucia, Queensland, Australia
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease Over Lifecourse, Villejuif, France
Université Paris Descartes INSERM UMR-S775 EPIGENETEC, Paris, France
Département d'informatique médicale Center Georges-François Leclerc, Dijon, France
Center Eugène Marquis Rennes, France
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Emilie Cordina-Duverger
Emilie Cordina-Duverger
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Environmental Epidemiology of Cancer, Villejuif, France
Université Paris-Sud UMRS 1018, Villejuif, France
Biostatistical Unit MRC, Cambridge, UK
School of Mathematics and Physics The University of Queensland, St Lucia, Queensland, Australia
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease Over Lifecourse, Villejuif, France
Université Paris Descartes INSERM UMR-S775 EPIGENETEC, Paris, France
Département d'informatique médicale Center Georges-François Leclerc, Dijon, France
Center Eugène Marquis Rennes, France
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Environmental Epidemiology of Cancer, Villejuif, France
Université Paris-Sud UMRS 1018, Villejuif, France
Biostatistical Unit MRC, Cambridge, UK
School of Mathematics and Physics The University of Queensland, St Lucia, Queensland, Australia
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease Over Lifecourse, Villejuif, France
Université Paris Descartes INSERM UMR-S775 EPIGENETEC, Paris, France
Département d'informatique médicale Center Georges-François Leclerc, Dijon, France
Center Eugène Marquis Rennes, France
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Université Paris-Sud UMRS 1018, Villejuif, France
Biostatistical Unit MRC, Cambridge, UK
School of Mathematics and Physics The University of Queensland, St Lucia, Queensland, Australia
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease Over Lifecourse, Villejuif, France
Université Paris Descartes INSERM UMR-S775 EPIGENETEC, Paris, France
Département d'informatique médicale Center Georges-François Leclerc, Dijon, France
Center Eugène Marquis Rennes, France
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Environmental Epidemiology of Cancer, Villejuif, France
Université Paris-Sud UMRS 1018, Villejuif, France
Biostatistical Unit MRC, Cambridge, UK
School of Mathematics and Physics The University of Queensland, St Lucia, Queensland, Australia
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease Over Lifecourse, Villejuif, France
Université Paris Descartes INSERM UMR-S775 EPIGENETEC, Paris, France
Département d'informatique médicale Center Georges-François Leclerc, Dijon, France
Center Eugène Marquis Rennes, France
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Marie Sanchez
Marie Sanchez
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Environmental Epidemiology of Cancer, Villejuif, France
Université Paris-Sud UMRS 1018, Villejuif, France
Biostatistical Unit MRC, Cambridge, UK
School of Mathematics and Physics The University of Queensland, St Lucia, Queensland, Australia
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease Over Lifecourse, Villejuif, France
Université Paris Descartes INSERM UMR-S775 EPIGENETEC, Paris, France
Département d'informatique médicale Center Georges-François Leclerc, Dijon, France
Center Eugène Marquis Rennes, France
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Environmental Epidemiology of Cancer, Villejuif, France
Université Paris-Sud UMRS 1018, Villejuif, France
Biostatistical Unit MRC, Cambridge, UK
School of Mathematics and Physics The University of Queensland, St Lucia, Queensland, Australia
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease Over Lifecourse, Villejuif, France
Université Paris Descartes INSERM UMR-S775 EPIGENETEC, Paris, France
Département d'informatique médicale Center Georges-François Leclerc, Dijon, France
Center Eugène Marquis Rennes, France
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Université Paris-Sud UMRS 1018, Villejuif, France
Biostatistical Unit MRC, Cambridge, UK
School of Mathematics and Physics The University of Queensland, St Lucia, Queensland, Australia
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease Over Lifecourse, Villejuif, France
Université Paris Descartes INSERM UMR-S775 EPIGENETEC, Paris, France
Département d'informatique médicale Center Georges-François Leclerc, Dijon, France
Center Eugène Marquis Rennes, France
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Environmental Epidemiology of Cancer, Villejuif, France
Université Paris-Sud UMRS 1018, Villejuif, France
Biostatistical Unit MRC, Cambridge, UK
School of Mathematics and Physics The University of Queensland, St Lucia, Queensland, Australia
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease Over Lifecourse, Villejuif, France
Université Paris Descartes INSERM UMR-S775 EPIGENETEC, Paris, France
Département d'informatique médicale Center Georges-François Leclerc, Dijon, France
Center Eugène Marquis Rennes, France
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Patrick Arveux
Patrick Arveux
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Environmental Epidemiology of Cancer, Villejuif, France
Université Paris-Sud UMRS 1018, Villejuif, France
Biostatistical Unit MRC, Cambridge, UK
School of Mathematics and Physics The University of Queensland, St Lucia, Queensland, Australia
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease Over Lifecourse, Villejuif, France
Université Paris Descartes INSERM UMR-S775 EPIGENETEC, Paris, France
Département d'informatique médicale Center Georges-François Leclerc, Dijon, France
Center Eugène Marquis Rennes, France
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Université Paris-Sud UMRS 1018, Villejuif, France
Biostatistical Unit MRC, Cambridge, UK
School of Mathematics and Physics The University of Queensland, St Lucia, Queensland, Australia
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease Over Lifecourse, Villejuif, France
Université Paris Descartes INSERM UMR-S775 EPIGENETEC, Paris, France
Département d'informatique médicale Center Georges-François Leclerc, Dijon, France
Center Eugène Marquis Rennes, France
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Pierre Kerbrat
Pierre Kerbrat
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Environmental Epidemiology of Cancer, Villejuif, France
Université Paris-Sud UMRS 1018, Villejuif, France
Biostatistical Unit MRC, Cambridge, UK
School of Mathematics and Physics The University of Queensland, St Lucia, Queensland, Australia
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease Over Lifecourse, Villejuif, France
Université Paris Descartes INSERM UMR-S775 EPIGENETEC, Paris, France
Département d'informatique médicale Center Georges-François Leclerc, Dijon, France
Center Eugène Marquis Rennes, France
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Université Paris-Sud UMRS 1018, Villejuif, France
Biostatistical Unit MRC, Cambridge, UK
School of Mathematics and Physics The University of Queensland, St Lucia, Queensland, Australia
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease Over Lifecourse, Villejuif, France
Université Paris Descartes INSERM UMR-S775 EPIGENETEC, Paris, France
Département d'informatique médicale Center Georges-François Leclerc, Dijon, France
Center Eugène Marquis Rennes, France
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Sylvia Richardson
Sylvia Richardson
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Environmental Epidemiology of Cancer, Villejuif, France
Université Paris-Sud UMRS 1018, Villejuif, France
Biostatistical Unit MRC, Cambridge, UK
School of Mathematics and Physics The University of Queensland, St Lucia, Queensland, Australia
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease Over Lifecourse, Villejuif, France
Université Paris Descartes INSERM UMR-S775 EPIGENETEC, Paris, France
Département d'informatique médicale Center Georges-François Leclerc, Dijon, France
Center Eugène Marquis Rennes, France
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Université Paris-Sud UMRS 1018, Villejuif, France
Biostatistical Unit MRC, Cambridge, UK
School of Mathematics and Physics The University of Queensland, St Lucia, Queensland, Australia
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease Over Lifecourse, Villejuif, France
Université Paris Descartes INSERM UMR-S775 EPIGENETEC, Paris, France
Département d'informatique médicale Center Georges-François Leclerc, Dijon, France
Center Eugène Marquis Rennes, France
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Pascal Guénel
Pascal Guénel
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Environmental Epidemiology of Cancer, Villejuif, France
Université Paris-Sud UMRS 1018, Villejuif, France
Biostatistical Unit MRC, Cambridge, UK
School of Mathematics and Physics The University of Queensland, St Lucia, Queensland, Australia
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease Over Lifecourse, Villejuif, France
Université Paris Descartes INSERM UMR-S775 EPIGENETEC, Paris, France
Département d'informatique médicale Center Georges-François Leclerc, Dijon, France
Center Eugène Marquis Rennes, France
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Environmental Epidemiology of Cancer, Villejuif, France
Université Paris-Sud UMRS 1018, Villejuif, France
Biostatistical Unit MRC, Cambridge, UK
School of Mathematics and Physics The University of Queensland, St Lucia, Queensland, Australia
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease Over Lifecourse, Villejuif, France
Université Paris Descartes INSERM UMR-S775 EPIGENETEC, Paris, France
Département d'informatique médicale Center Georges-François Leclerc, Dijon, France
Center Eugène Marquis Rennes, France
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Université Paris-Sud UMRS 1018, Villejuif, France
Biostatistical Unit MRC, Cambridge, UK
School of Mathematics and Physics The University of Queensland, St Lucia, Queensland, Australia
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease Over Lifecourse, Villejuif, France
Université Paris Descartes INSERM UMR-S775 EPIGENETEC, Paris, France
Département d'informatique médicale Center Georges-François Leclerc, Dijon, France
Center Eugène Marquis Rennes, France
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Environmental Epidemiology of Cancer, Villejuif, France
Université Paris-Sud UMRS 1018, Villejuif, France
Biostatistical Unit MRC, Cambridge, UK
School of Mathematics and Physics The University of Queensland, St Lucia, Queensland, Australia
Inserm CESP Center for Research in Epidemiology and Population Health, U1018, Epidemiology of Diabetes, Obesity and Chronic Kidney Disease Over Lifecourse, Villejuif, France
Université Paris Descartes INSERM UMR-S775 EPIGENETEC, Paris, France
Département d'informatique médicale Center Georges-François Leclerc, Dijon, France
Center Eugène Marquis Rennes, France
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-regulated feedback loop. The circadian rhythm pathway plays a key role in the maintenance of various endocrine, physiological, and behavioral functions including cell cycle regulation, hormone secretion, body temperature, and sleep/wake cycle. The disruption of the
Zsofia Kiss
Zsofia Kiss
VA Northern California Health Care System, Mather, California, USA
Department of Urology, University of California at Davis, Sacramento, California, USA
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Department of Urology, University of California at Davis, Sacramento, California, USA
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Paramita M Ghosh
Paramita M Ghosh
VA Northern California Health Care System, Mather, California, USA
Department of Urology, University of California at Davis, Sacramento, California, USA
Department of Biochemistry and Molecular Medicine, University of California at Davis, Sacramento, California, USA
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Department of Urology, University of California at Davis, Sacramento, California, USA
Department of Biochemistry and Molecular Medicine, University of California at Davis, Sacramento, California, USA
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responsible for maintaining circadian rhythms may result in deregulation of clock-associated biological processes, such as androgen expression, and consequently influence an individual’s risk of prostate cancer’ ( Zhu et al . 2006 ). In support of a role for
Ewan M Stephenson
Ewan M Stephenson
Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research, Singapore
Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry, UK
Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore
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Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry, UK
Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore
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Laura E J Usselmann
Laura E J Usselmann
Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry, UK
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Vinay Tergaonkar
Vinay Tergaonkar
Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research, Singapore
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David M Virshup
David M Virshup
Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore
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Robert Dallmann
Robert Dallmann
Division of Biomedical Sciences, Warwick Medical School, University of Warwick, Coventry, UK
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centuries since, oscillations that coordinate normal physiology with the 24 h light:24 h darkness cycle have been discovered across the kingdoms of life ( Rosbash 2009 ). Disrupted circadian rhythms contribute to many human diseases including diabetes
Rebecca B Riggins
Rebecca B Riggins
Lombardi Comprehensive Cancer Center and Department of Oncology, Department of Physiology and Biophysics, Georgetown University School of Medicine, 3970 Reservoir Road NW, Washington, District of Columbia 20057, USA
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Mary M Mazzotta
Mary M Mazzotta
Lombardi Comprehensive Cancer Center and Department of Oncology, Department of Physiology and Biophysics, Georgetown University School of Medicine, 3970 Reservoir Road NW, Washington, District of Columbia 20057, USA
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Omar Z Maniya
Omar Z Maniya
Lombardi Comprehensive Cancer Center and Department of Oncology, Department of Physiology and Biophysics, Georgetown University School of Medicine, 3970 Reservoir Road NW, Washington, District of Columbia 20057, USA
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Robert Clarke
Robert Clarke
Lombardi Comprehensive Cancer Center and Department of Oncology, Department of Physiology and Biophysics, Georgetown University School of Medicine, 3970 Reservoir Road NW, Washington, District of Columbia 20057, USA
Lombardi Comprehensive Cancer Center and Department of Oncology, Department of Physiology and Biophysics, Georgetown University School of Medicine, 3970 Reservoir Road NW, Washington, District of Columbia 20057, USA
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Lombardi Comprehensive Cancer Center and Department of Oncology, Department of Physiology and Biophysics, Georgetown University School of Medicine, 3970 Reservoir Road NW, Washington, District of Columbia 20057, USA
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regulates metabolism and circadian rhythm ( Duez & Staels 2009 ). Despite its orphan status, Rev-Erbα and the related Rev-Erbβ (NR1D2) are known to bind heme ( Burris 2008 ). Rev-Erbα is localized to chromosome 17q21, a region that is frequently amplified in
Christina Wei
Christina Wei
St George’s University Hospital, NHS Foundation Trust, London, UK
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Elizabeth C Crowne
Elizabeth C Crowne
Bristol Royal Hospital for Children, University Hospitals Bristol, NHS Foundation Trust, Bristol, UK
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.6–10 year FU: 3.6–10 year Age at FU: 6.9–18.2 year RT: all had 18.9 (18–24) Gy, 10–12# ITT 24 h ACTH and cortisol profiling 20-min intervals • ITT: normal peak cortisol responses Profiles: normal preserved circadian rhythm ACTH
Jennifer F Barger
Jennifer F Barger
Department of Cancer and Cell Biology, University of Cincinnati, Cincinnati, Ohio 45267, USA
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David R Plas
David R Plas
Department of Cancer and Cell Biology, University of Cincinnati, Cincinnati, Ohio 45267, USA
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energetic demand. Period proteins associate with cryptochrome (CRY) proteins to regulate the activity of the central circadian rhythm transcription factors BMAL1 and Clock. Circadian rhythm is established through a negative feedback loop in which period
Ajay-Mohan Mohan
Ajay-Mohan Mohan
Department of Nuclear Medicine, Charité – Universitätsmedizin Berlin, Berlin, Germany
Berlin Experimental Radionuclide Imaging Center (BERIC), Charité - Universitätsmedizin Berlin, Berlin, Germany
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Berlin Experimental Radionuclide Imaging Center (BERIC), Charité - Universitätsmedizin Berlin, Berlin, Germany
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Sonal Prasad
Sonal Prasad
Department of Nuclear Medicine, Charité – Universitätsmedizin Berlin, Berlin, Germany
Berlin Experimental Radionuclide Imaging Center (BERIC), Charité - Universitätsmedizin Berlin, Berlin, Germany
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Berlin Experimental Radionuclide Imaging Center (BERIC), Charité - Universitätsmedizin Berlin, Berlin, Germany
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Fabian Schmitz-Peiffer
Fabian Schmitz-Peiffer
Department of Nuclear Medicine, Charité – Universitätsmedizin Berlin, Berlin, Germany
Berlin Experimental Radionuclide Imaging Center (BERIC), Charité - Universitätsmedizin Berlin, Berlin, Germany
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Berlin Experimental Radionuclide Imaging Center (BERIC), Charité - Universitätsmedizin Berlin, Berlin, Germany
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Catharina Lange
Catharina Lange
Department of Nuclear Medicine, Charité – Universitätsmedizin Berlin, Berlin, Germany
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Mathias Lukas
Mathias Lukas
Department of Nuclear Medicine, Charité – Universitätsmedizin Berlin, Berlin, Germany
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Eva J Koziolek
Eva J Koziolek
Department of Nuclear Medicine, Charité – Universitätsmedizin Berlin, Berlin, Germany
German Cancer Consortium (DKTK), partner site Berlin, Berlin, Germany
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German Cancer Consortium (DKTK), partner site Berlin, Berlin, Germany
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Jakob Albrecht
Jakob Albrecht
Department of Nuclear Medicine, Charité – Universitätsmedizin Berlin, Berlin, Germany
Berlin Experimental Radionuclide Imaging Center (BERIC), Charité - Universitätsmedizin Berlin, Berlin, Germany
German Cancer Consortium (DKTK), partner site Berlin, Berlin, Germany
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Berlin Experimental Radionuclide Imaging Center (BERIC), Charité - Universitätsmedizin Berlin, Berlin, Germany
German Cancer Consortium (DKTK), partner site Berlin, Berlin, Germany
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Daniel Messroghli
Daniel Messroghli
Department of Internal Medicine - Cardiology, Deutsches Herzzentrum Berlin, Berlin, Germany
Preclinical MRI Center, Charité - Universitätsmedizin Berlin, Berlin, Germany
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Preclinical MRI Center, Charité - Universitätsmedizin Berlin, Berlin, Germany
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Ulrike Stein
Ulrike Stein
German Cancer Consortium (DKTK), partner site Berlin, Berlin, Germany
Experimental and Clinical Research Center, Charité-Universitätsmedizin Berlin, and Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, Translational Oncology of Solid Tumours, Berlin, Germany
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Experimental and Clinical Research Center, Charité-Universitätsmedizin Berlin, and Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association, Translational Oncology of Solid Tumours, Berlin, Germany
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Matthias Ilmer
Matthias Ilmer
German Cancer Consortium (DKTK), partner site Berlin, Berlin, Germany
Department of General, Visceral, and Transplantation Surgery, University Hospital, LMU Munich, Munich, Germany
German Cancer Research Center (DKFZ), Heidelberg, Germany
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Department of General, Visceral, and Transplantation Surgery, University Hospital, LMU Munich, Munich, Germany
German Cancer Research Center (DKFZ), Heidelberg, Germany
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Katharina Wang
Katharina Wang
Department of Medicine IV, University Hospital, LMU Munich, Munich, Germany
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Laura Schober
Laura Schober
Department of Medicine IV, University Hospital, LMU Munich, Munich, Germany
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Astrid Reul
Astrid Reul
Department of Endocrinology, Diabetology and Clinical Nutrition, University Hospital, University of Zurich (USZ) and University of Zurich (UZH), Zurich, Switzerland
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Julian Maurer
Julian Maurer
Department of Medicine IV, University Hospital, LMU Munich, Munich, Germany
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Juliane Friemel
Juliane Friemel
Department of Pathology and Molecular Pathology, University Zurich and University Hospital Zürich, Zurich, Switzerland
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Achim Weber
Achim Weber
Department of Pathology and Molecular Pathology, University Zurich and University Hospital Zürich, Zurich, Switzerland
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Richard A Zuellig
Richard A Zuellig
Department of Endocrinology, Diabetology and Clinical Nutrition, University Hospital, University of Zurich (USZ) and University of Zurich (UZH), Zurich, Switzerland
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Constanze Hantel
Constanze Hantel
Department of Medicine IV, University Hospital, LMU Munich, Munich, Germany
Department of Endocrinology, Diabetology and Clinical Nutrition, University Hospital, University of Zurich (USZ) and University of Zurich (UZH), Zurich, Switzerland
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Department of Endocrinology, Diabetology and Clinical Nutrition, University Hospital, University of Zurich (USZ) and University of Zurich (UZH), Zurich, Switzerland
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Ralph Fritsch
Ralph Fritsch
Department of Medical Oncology and Hematology, University Zurich and University Hospital Zürich, Zurich, Switzerland
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Martin Reincke
Martin Reincke
Department of Medicine IV, University Hospital, LMU Munich, Munich, Germany
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Karel Pacak
Karel Pacak
Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institute of Health (NIH), Bethesda, Maryland, USA
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Ashley B Grossman
Ashley B Grossman
Green Templeton College, University of Oxford, London, United Kingdom
Centre for Endocrinology, Barts and the London School of Medicine, Queen Mary University of London, United Kingdom
ENETS Centre of Excellence, Royal Free Hospital, London, United Kingdom
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Centre for Endocrinology, Barts and the London School of Medicine, Queen Mary University of London, United Kingdom
ENETS Centre of Excellence, Royal Free Hospital, London, United Kingdom
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Christoph J Auernhammer
Christoph J Auernhammer
Department of Medicine IV, University Hospital, LMU Munich, Munich, Germany
ENETS Centre of Excellence, Interdisciplinary Center of Neuroendocrine Tumours of the GastroEnteroPancreatic System at the University Hospital of Munich, Munich, Germany
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ENETS Centre of Excellence, Interdisciplinary Center of Neuroendocrine Tumours of the GastroEnteroPancreatic System at the University Hospital of Munich, Munich, Germany
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Felix Beuschlein
Felix Beuschlein
Department of Endocrinology, Diabetology and Clinical Nutrition, University Hospital, University of Zurich (USZ) and University of Zurich (UZH), Zurich, Switzerland
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Winfried Brenner
Winfried Brenner
Department of Nuclear Medicine, Charité – Universitätsmedizin Berlin, Berlin, Germany
Berlin Experimental Radionuclide Imaging Center (BERIC), Charité - Universitätsmedizin Berlin, Berlin, Germany
German Cancer Consortium (DKTK), partner site Berlin, Berlin, Germany
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Berlin Experimental Radionuclide Imaging Center (BERIC), Charité - Universitätsmedizin Berlin, Berlin, Germany
German Cancer Consortium (DKTK), partner site Berlin, Berlin, Germany
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Nicola Beindorff
Nicola Beindorff
Berlin Experimental Radionuclide Imaging Center (BERIC), Charité - Universitätsmedizin Berlin, Berlin, Germany
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Svenja Nölting
Svenja Nölting
Department of Medicine IV, University Hospital, LMU Munich, Munich, Germany
Department of Endocrinology, Diabetology and Clinical Nutrition, University Hospital, University of Zurich (USZ) and University of Zurich (UZH), Zurich, Switzerland
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Department of Endocrinology, Diabetology and Clinical Nutrition, University Hospital, University of Zurich (USZ) and University of Zurich (UZH), Zurich, Switzerland
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deficient’ (SCID) mice. Animals were housed at the Berlin Experimental Radionuclide Imaging Center (BERIC) with a 12-h light–12-h darkness circadian rhythm. The husbandry conditions have been described in detail previously ( Beindorff et al. 2018
