Search Results

You are looking at 1 - 10 of 49 items for :

  • "gene methylation" x
  • Refine by access: All content x
Clear All
Ying-Cheng Chiang Department of Obstetrics and Gynecology, Graduate Institute of Clinical Medicine, Department of Anesthesiology, Department of Obstetrics and Gynecology, Genomics Research Center, Graduate Institute of Oncology, College of Medicine, National Taiwan University, Taipei, Taiwan
Department of Obstetrics and Gynecology, Graduate Institute of Clinical Medicine, Department of Anesthesiology, Department of Obstetrics and Gynecology, Genomics Research Center, Graduate Institute of Oncology, College of Medicine, National Taiwan University, Taipei, Taiwan

Search for other papers by Ying-Cheng Chiang in
Google Scholar
PubMed
Close
,
Ming-Cheng Chang Department of Obstetrics and Gynecology, Graduate Institute of Clinical Medicine, Department of Anesthesiology, Department of Obstetrics and Gynecology, Genomics Research Center, Graduate Institute of Oncology, College of Medicine, National Taiwan University, Taipei, Taiwan
Department of Obstetrics and Gynecology, Graduate Institute of Clinical Medicine, Department of Anesthesiology, Department of Obstetrics and Gynecology, Genomics Research Center, Graduate Institute of Oncology, College of Medicine, National Taiwan University, Taipei, Taiwan

Search for other papers by Ming-Cheng Chang in
Google Scholar
PubMed
Close
,
Pao-Jen Chen Department of Obstetrics and Gynecology, Graduate Institute of Clinical Medicine, Department of Anesthesiology, Department of Obstetrics and Gynecology, Genomics Research Center, Graduate Institute of Oncology, College of Medicine, National Taiwan University, Taipei, Taiwan

Search for other papers by Pao-Jen Chen in
Google Scholar
PubMed
Close
,
Meei-Maan Wu Department of Obstetrics and Gynecology, Graduate Institute of Clinical Medicine, Department of Anesthesiology, Department of Obstetrics and Gynecology, Genomics Research Center, Graduate Institute of Oncology, College of Medicine, National Taiwan University, Taipei, Taiwan
Department of Obstetrics and Gynecology, Graduate Institute of Clinical Medicine, Department of Anesthesiology, Department of Obstetrics and Gynecology, Genomics Research Center, Graduate Institute of Oncology, College of Medicine, National Taiwan University, Taipei, Taiwan

Search for other papers by Meei-Maan Wu in
Google Scholar
PubMed
Close
,
Chang-Yao Hsieh Department of Obstetrics and Gynecology, Graduate Institute of Clinical Medicine, Department of Anesthesiology, Department of Obstetrics and Gynecology, Genomics Research Center, Graduate Institute of Oncology, College of Medicine, National Taiwan University, Taipei, Taiwan

Search for other papers by Chang-Yao Hsieh in
Google Scholar
PubMed
Close
,
Wen-Fang Cheng Department of Obstetrics and Gynecology, Graduate Institute of Clinical Medicine, Department of Anesthesiology, Department of Obstetrics and Gynecology, Genomics Research Center, Graduate Institute of Oncology, College of Medicine, National Taiwan University, Taipei, Taiwan
Department of Obstetrics and Gynecology, Graduate Institute of Clinical Medicine, Department of Anesthesiology, Department of Obstetrics and Gynecology, Genomics Research Center, Graduate Institute of Oncology, College of Medicine, National Taiwan University, Taipei, Taiwan
Department of Obstetrics and Gynecology, Graduate Institute of Clinical Medicine, Department of Anesthesiology, Department of Obstetrics and Gynecology, Genomics Research Center, Graduate Institute of Oncology, College of Medicine, National Taiwan University, Taipei, Taiwan

Search for other papers by Wen-Fang Cheng in
Google Scholar
PubMed
Close
, and
Chi-An Chen Department of Obstetrics and Gynecology, Graduate Institute of Clinical Medicine, Department of Anesthesiology, Department of Obstetrics and Gynecology, Genomics Research Center, Graduate Institute of Oncology, College of Medicine, National Taiwan University, Taipei, Taiwan

Search for other papers by Chi-An Chen in
Google Scholar
PubMed
Close

hypothesis proposed that there could be two possible tumor pathways in the carcinogenesis of ovarian carcinoma including type I and II tumors ( Kurman & Shih Ie 2010 ). Distinct gene methylation profiles may exist between these two types of tumor pathway

Free access
Peng Hou Laboratory for Cellular and Molecular Thyroid Research, Division of Endocrinology and Metabolism, The Johns Hopkins University School of Medicine, 1830 East Monument Street, Suite 333, Baltimore, Maryland 21287, USA

Search for other papers by Peng Hou in
Google Scholar
PubMed
Close
,
Dingxie Liu Laboratory for Cellular and Molecular Thyroid Research, Division of Endocrinology and Metabolism, The Johns Hopkins University School of Medicine, 1830 East Monument Street, Suite 333, Baltimore, Maryland 21287, USA

Search for other papers by Dingxie Liu in
Google Scholar
PubMed
Close
, and
Mingzhao Xing Laboratory for Cellular and Molecular Thyroid Research, Division of Endocrinology and Metabolism, The Johns Hopkins University School of Medicine, 1830 East Monument Street, Suite 333, Baltimore, Maryland 21287, USA

Search for other papers by Mingzhao Xing in
Google Scholar
PubMed
Close

, 2007 a ). The specific molecular mechanisms underlying PTC tumorigenesis driven by the BRAF mutation have not been well understood. This is particularly the case in epigenetic aspects. For example, the role of aberrant gene methylation and its extent

Free access
Nora Sahnane Section of Anatomic Pathology, CRIBI Biotechnology Center, Department of Molecular Medicine, Department of Pathology, Department of Surgical and Morphological Sciences, University of Insubria, Via O. Rossi, 9, 21100 Varese, Italy

Search for other papers by Nora Sahnane in
Google Scholar
PubMed
Close
,
Daniela Furlan Section of Anatomic Pathology, CRIBI Biotechnology Center, Department of Molecular Medicine, Department of Pathology, Department of Surgical and Morphological Sciences, University of Insubria, Via O. Rossi, 9, 21100 Varese, Italy

Search for other papers by Daniela Furlan in
Google Scholar
PubMed
Close
,
Matilde Monti Section of Anatomic Pathology, CRIBI Biotechnology Center, Department of Molecular Medicine, Department of Pathology, Department of Surgical and Morphological Sciences, University of Insubria, Via O. Rossi, 9, 21100 Varese, Italy

Search for other papers by Matilde Monti in
Google Scholar
PubMed
Close
,
Chiara Romualdi Section of Anatomic Pathology, CRIBI Biotechnology Center, Department of Molecular Medicine, Department of Pathology, Department of Surgical and Morphological Sciences, University of Insubria, Via O. Rossi, 9, 21100 Varese, Italy

Search for other papers by Chiara Romualdi in
Google Scholar
PubMed
Close
,
Alessandro Vanoli Section of Anatomic Pathology, CRIBI Biotechnology Center, Department of Molecular Medicine, Department of Pathology, Department of Surgical and Morphological Sciences, University of Insubria, Via O. Rossi, 9, 21100 Varese, Italy

Search for other papers by Alessandro Vanoli in
Google Scholar
PubMed
Close
,
Emanuela Vicari Section of Anatomic Pathology, CRIBI Biotechnology Center, Department of Molecular Medicine, Department of Pathology, Department of Surgical and Morphological Sciences, University of Insubria, Via O. Rossi, 9, 21100 Varese, Italy

Search for other papers by Emanuela Vicari in
Google Scholar
PubMed
Close
,
Enrico Solcia Section of Anatomic Pathology, CRIBI Biotechnology Center, Department of Molecular Medicine, Department of Pathology, Department of Surgical and Morphological Sciences, University of Insubria, Via O. Rossi, 9, 21100 Varese, Italy

Search for other papers by Enrico Solcia in
Google Scholar
PubMed
Close
,
Carlo Capella Section of Anatomic Pathology, CRIBI Biotechnology Center, Department of Molecular Medicine, Department of Pathology, Department of Surgical and Morphological Sciences, University of Insubria, Via O. Rossi, 9, 21100 Varese, Italy

Search for other papers by Carlo Capella in
Google Scholar
PubMed
Close
,
Fausto Sessa Section of Anatomic Pathology, CRIBI Biotechnology Center, Department of Molecular Medicine, Department of Pathology, Department of Surgical and Morphological Sciences, University of Insubria, Via O. Rossi, 9, 21100 Varese, Italy

Search for other papers by Fausto Sessa in
Google Scholar
PubMed
Close
, and
Stefano La Rosa Section of Anatomic Pathology, CRIBI Biotechnology Center, Department of Molecular Medicine, Department of Pathology, Department of Surgical and Morphological Sciences, University of Insubria, Via O. Rossi, 9, 21100 Varese, Italy

Search for other papers by Stefano La Rosa in
Google Scholar
PubMed
Close

abundant intraepithelial lymphocytes. Although they can be recognized in the H&E-stained section (A), they become much more evident in the CD3-immunostained section (B) (original magnification 250×). MMR gene methylation To investigate whether the loss of

Free access
C D E Margetts
Search for other papers by C D E Margetts in
Google Scholar
PubMed
Close
,
D Astuti
Search for other papers by D Astuti in
Google Scholar
PubMed
Close
,
D C Gentle
Search for other papers by D C Gentle in
Google Scholar
PubMed
Close
,
W N Cooper
Search for other papers by W N Cooper in
Google Scholar
PubMed
Close
,
A Cascon
Search for other papers by A Cascon in
Google Scholar
PubMed
Close
,
D Catchpoole
Search for other papers by D Catchpoole in
Google Scholar
PubMed
Close
,
M Robledo
Search for other papers by M Robledo in
Google Scholar
PubMed
Close
,
H P H Neumann
Search for other papers by H P H Neumann in
Google Scholar
PubMed
Close
,
F Latif
Search for other papers by F Latif in
Google Scholar
PubMed
Close
, and
E R Maher
Search for other papers by E R Maher in
Google Scholar
PubMed
Close

are summarized in Table 1 and individual tumour results are given in Table 2 (all methylation-positive tumours also demonstrated unmethylated alleles). The frequency of gene methylation varied from 8% ( FLIP ) to 82% ( HIC1 ), with methylation in

Free access
De-tao Yin Department of Thyroid Surgery, Key Discipline Laboratory of Clinical Medicine Henan, Department of Endocrinology, Division of Radiobiology, Division of Endocrinology and Metabolism, The First Affiliated Hospital, Zhengzhou University, Zhengzhou 450052, People's Republic of China
Department of Thyroid Surgery, Key Discipline Laboratory of Clinical Medicine Henan, Department of Endocrinology, Division of Radiobiology, Division of Endocrinology and Metabolism, The First Affiliated Hospital, Zhengzhou University, Zhengzhou 450052, People's Republic of China

Search for other papers by De-tao Yin in
Google Scholar
PubMed
Close
,
Wenxun Wu Department of Thyroid Surgery, Key Discipline Laboratory of Clinical Medicine Henan, Department of Endocrinology, Division of Radiobiology, Division of Endocrinology and Metabolism, The First Affiliated Hospital, Zhengzhou University, Zhengzhou 450052, People's Republic of China

Search for other papers by Wenxun Wu in
Google Scholar
PubMed
Close
,
Mingchuang Li Department of Thyroid Surgery, Key Discipline Laboratory of Clinical Medicine Henan, Department of Endocrinology, Division of Radiobiology, Division of Endocrinology and Metabolism, The First Affiliated Hospital, Zhengzhou University, Zhengzhou 450052, People's Republic of China
Department of Thyroid Surgery, Key Discipline Laboratory of Clinical Medicine Henan, Department of Endocrinology, Division of Radiobiology, Division of Endocrinology and Metabolism, The First Affiliated Hospital, Zhengzhou University, Zhengzhou 450052, People's Republic of China

Search for other papers by Mingchuang Li in
Google Scholar
PubMed
Close
,
Qi-en Wang Department of Thyroid Surgery, Key Discipline Laboratory of Clinical Medicine Henan, Department of Endocrinology, Division of Radiobiology, Division of Endocrinology and Metabolism, The First Affiliated Hospital, Zhengzhou University, Zhengzhou 450052, People's Republic of China

Search for other papers by Qi-en Wang in
Google Scholar
PubMed
Close
,
Hongqiang Li Department of Thyroid Surgery, Key Discipline Laboratory of Clinical Medicine Henan, Department of Endocrinology, Division of Radiobiology, Division of Endocrinology and Metabolism, The First Affiliated Hospital, Zhengzhou University, Zhengzhou 450052, People's Republic of China
Department of Thyroid Surgery, Key Discipline Laboratory of Clinical Medicine Henan, Department of Endocrinology, Division of Radiobiology, Division of Endocrinology and Metabolism, The First Affiliated Hospital, Zhengzhou University, Zhengzhou 450052, People's Republic of China

Search for other papers by Hongqiang Li in
Google Scholar
PubMed
Close
,
Yongfei Wang Department of Thyroid Surgery, Key Discipline Laboratory of Clinical Medicine Henan, Department of Endocrinology, Division of Radiobiology, Division of Endocrinology and Metabolism, The First Affiliated Hospital, Zhengzhou University, Zhengzhou 450052, People's Republic of China
Department of Thyroid Surgery, Key Discipline Laboratory of Clinical Medicine Henan, Department of Endocrinology, Division of Radiobiology, Division of Endocrinology and Metabolism, The First Affiliated Hospital, Zhengzhou University, Zhengzhou 450052, People's Republic of China

Search for other papers by Yongfei Wang in
Google Scholar
PubMed
Close
,
Yifeng Tang Department of Thyroid Surgery, Key Discipline Laboratory of Clinical Medicine Henan, Department of Endocrinology, Division of Radiobiology, Division of Endocrinology and Metabolism, The First Affiliated Hospital, Zhengzhou University, Zhengzhou 450052, People's Republic of China
Department of Thyroid Surgery, Key Discipline Laboratory of Clinical Medicine Henan, Department of Endocrinology, Division of Radiobiology, Division of Endocrinology and Metabolism, The First Affiliated Hospital, Zhengzhou University, Zhengzhou 450052, People's Republic of China

Search for other papers by Yifeng Tang in
Google Scholar
PubMed
Close
, and
Mingzhao Xing Department of Thyroid Surgery, Key Discipline Laboratory of Clinical Medicine Henan, Department of Endocrinology, Division of Radiobiology, Division of Endocrinology and Metabolism, The First Affiliated Hospital, Zhengzhou University, Zhengzhou 450052, People's Republic of China

Search for other papers by Mingzhao Xing in
Google Scholar
PubMed
Close

methylation in human breast cancer . BMC Cancer 9 217 . ( doi:10.1186/1471-2407-9-217 ). Xing M 2007 Gene methylation in thyroid tumorigenesis . Endocrinology 148 948 – 953 . ( doi:10.1210/en.2006-0927 ). Yin DT Wang L Sun J Yin F Yan

Free access
W E Farrell Centre for Cell and Molecular Medicine, School of Postgraduate Medicine, Keele University, North Staffordshire Hospital, Stoke-on-Trent, UK. w.e.farrell@keele.ac.uk

Search for other papers by W E Farrell in
Google Scholar
PubMed
Close
,
D J Simpson Centre for Cell and Molecular Medicine, School of Postgraduate Medicine, Keele University, North Staffordshire Hospital, Stoke-on-Trent, UK. w.e.farrell@keele.ac.uk

Search for other papers by D J Simpson in
Google Scholar
PubMed
Close
,
S J Frost Centre for Cell and Molecular Medicine, School of Postgraduate Medicine, Keele University, North Staffordshire Hospital, Stoke-on-Trent, UK. w.e.farrell@keele.ac.uk

Search for other papers by S J Frost in
Google Scholar
PubMed
Close
, and
R N Clayton Centre for Cell and Molecular Medicine, School of Postgraduate Medicine, Keele University, North Staffordshire Hospital, Stoke-on-Trent, UK. w.e.farrell@keele.ac.uk

Search for other papers by R N Clayton in
Google Scholar
PubMed
Close

Methylation is essential for embryonic development, however aberrant methylation of CpG islands associated with the tumour suppressor genes (TSGs) and leading to gene silencing is found in numerous tumour types. The TSG p16/CDKN2A is involved in the genesis of many tumour types and frequent methylation of the CpG island of the p16/CDKN2A gene is associated with loss of protein expression in pituitary tumours. In addition, CpG sites are mutational hotspots and abnormal methylation patterns have been shown to lead to genetic instability, predisposing to, and preceding allelic loss. Although several studies of pituitary tumours have shown loss of genetic material at known and putative TSGs loci, studies of the retained alleles have revealed infrequent mutation. Equally, for several other TSGs no mechanisms have been described for their reduced expression. Methylation may represent a unifying theme, responsible in some cases for an absence or reduced expression and in other cases predisposing to allelic loss that may or may not encompass a TSG. In several tumour types treatment of tumours or their cognate cell lines with demethylating agents induces expression of previously methylated genes. Using the mouse corticotroph cell line AtT20 as a model system, transfection studies showed restoration of growth control through induction of ectopically expressed p16/CDKN2A. These effects were reversed by prior in vitro methylation of the constructs' CpG sites within the coding region of this gene. Methylation of an otherwise unmethylated CpG island renders a gene transcriptionally incompetent and clinically these genes represent attractive therapeutic targets since the gene is neither lost nor mutated, but may be reactivated. Future studies will no doubt describe more efficacious pharmacological interventions and identify the mechanisms responsible for the abnormal methylation patterns seen in tumours including those of pituitary origin.

Free access
Kristina Warton Garvan Institute of Medical Research, Chris O'Brien Lifehouse, The Kinghorn Cancer Centre and St Vincent's Clinical School, 370 Victoria Street, Darlinghurst, Sydeny, New South Wales, Australia

Search for other papers by Kristina Warton in
Google Scholar
PubMed
Close
,
Kate L Mahon Garvan Institute of Medical Research, Chris O'Brien Lifehouse, The Kinghorn Cancer Centre and St Vincent's Clinical School, 370 Victoria Street, Darlinghurst, Sydeny, New South Wales, Australia
Garvan Institute of Medical Research, Chris O'Brien Lifehouse, The Kinghorn Cancer Centre and St Vincent's Clinical School, 370 Victoria Street, Darlinghurst, Sydeny, New South Wales, Australia

Search for other papers by Kate L Mahon in
Google Scholar
PubMed
Close
, and
Goli Samimi Garvan Institute of Medical Research, Chris O'Brien Lifehouse, The Kinghorn Cancer Centre and St Vincent's Clinical School, 370 Victoria Street, Darlinghurst, Sydeny, New South Wales, Australia

Search for other papers by Goli Samimi in
Google Scholar
PubMed
Close

, GSTP1 , STRATIFIN and MDR1 ) in six consecutive serum samples from breast cancer patients undergoing chemotherapy treatment. A correlation between reduction in total gene methylation and reduction in tumor volume in the respondents group was observed

Open access
Olga Karapanou Endocrine Department, 401 General Military Hospital of Athens, Athens, Greece

Search for other papers by Olga Karapanou in
Google Scholar
PubMed
Close
,
George Simeakis Endocrine Department, 401 General Military Hospital of Athens, Athens, Greece
Department of Clinical Therapeutics, Alexandra Hospital Athens University School of Medicine, Endocrine Unit, Athens, Greece

Search for other papers by George Simeakis in
Google Scholar
PubMed
Close
,
Barbara Vlassopoulou Endocrine Department, Evangelismos Athens General Hospital, Athens, Greece

Search for other papers by Barbara Vlassopoulou in
Google Scholar
PubMed
Close
,
Maria Alevizaki Department of Clinical Therapeutics, Alexandra Hospital Athens University School of Medicine, Endocrine Unit, Athens, Greece

Search for other papers by Maria Alevizaki in
Google Scholar
PubMed
Close
, and
Katerina Saltiki Department of Clinical Therapeutics, Alexandra Hospital Athens University School of Medicine, Endocrine Unit, Athens, Greece

Search for other papers by Katerina Saltiki in
Google Scholar
PubMed
Close

methylation of NIS promoter contributes to loss of iodide uptake, that is RAI resistance ( Xing 2007 ). It has been demonstrated that iodide uptake in dedifferentiated thyroid tumors is related to NIS gene methylation status ( Venkataraman et al. 1999

Free access
Antoinette S Perry
Search for other papers by Antoinette S Perry in
Google Scholar
PubMed
Close
,
Ruth Foley
Search for other papers by Ruth Foley in
Google Scholar
PubMed
Close
,
Karen Woodson
Search for other papers by Karen Woodson in
Google Scholar
PubMed
Close
, and
Mark Lawler
Search for other papers by Mark Lawler in
Google Scholar
PubMed
Close

body of evidence shows an association between specific gene methylation and clinicopathologic indicators of poor prognosis in CaP. We present a broad review of the major findings of these studies. In addition, we discuss recent investigations of genome

Free access
Yuriko Mori Division of Gastroenterology, Division of Gastroenterology, Division of Gastroenterology, Division of Gastroenterology, Section of Gastroenterology, Department of Surgery, Division of Gastroenterology, Department of Medicine

Search for other papers by Yuriko Mori in
Google Scholar
PubMed
Close
,
Alexandru V Olaru Division of Gastroenterology, Division of Gastroenterology, Division of Gastroenterology, Division of Gastroenterology, Section of Gastroenterology, Department of Surgery, Division of Gastroenterology, Department of Medicine

Search for other papers by Alexandru V Olaru in
Google Scholar
PubMed
Close
,
Yulan Cheng Division of Gastroenterology, Division of Gastroenterology, Division of Gastroenterology, Division of Gastroenterology, Section of Gastroenterology, Department of Surgery, Division of Gastroenterology, Department of Medicine

Search for other papers by Yulan Cheng in
Google Scholar
PubMed
Close
,
Rachana Agarwal Division of Gastroenterology, Division of Gastroenterology, Division of Gastroenterology, Division of Gastroenterology, Section of Gastroenterology, Department of Surgery, Division of Gastroenterology, Department of Medicine

Search for other papers by Rachana Agarwal in
Google Scholar
PubMed
Close
,
Jian Yang Division of Gastroenterology, Division of Gastroenterology, Division of Gastroenterology, Division of Gastroenterology, Section of Gastroenterology, Department of Surgery, Division of Gastroenterology, Department of Medicine

Search for other papers by Jian Yang in
Google Scholar
PubMed
Close
,
Delgermaa Luvsanjav Division of Gastroenterology, Division of Gastroenterology, Division of Gastroenterology, Division of Gastroenterology, Section of Gastroenterology, Department of Surgery, Division of Gastroenterology, Department of Medicine

Search for other papers by Delgermaa Luvsanjav in
Google Scholar
PubMed
Close
,
Wayne Yu Division of Gastroenterology, Division of Gastroenterology, Division of Gastroenterology, Division of Gastroenterology, Section of Gastroenterology, Department of Surgery, Division of Gastroenterology, Department of Medicine

Search for other papers by Wayne Yu in
Google Scholar
PubMed
Close
,
Florin M Selaru Division of Gastroenterology, Division of Gastroenterology, Division of Gastroenterology, Division of Gastroenterology, Section of Gastroenterology, Department of Surgery, Division of Gastroenterology, Department of Medicine

Search for other papers by Florin M Selaru in
Google Scholar
PubMed
Close
,
Susan Hutfless Division of Gastroenterology, Division of Gastroenterology, Division of Gastroenterology, Division of Gastroenterology, Section of Gastroenterology, Department of Surgery, Division of Gastroenterology, Department of Medicine

Search for other papers by Susan Hutfless in
Google Scholar
PubMed
Close
,
Mark Lazarev Division of Gastroenterology, Division of Gastroenterology, Division of Gastroenterology, Division of Gastroenterology, Section of Gastroenterology, Department of Surgery, Division of Gastroenterology, Department of Medicine

Search for other papers by Mark Lazarev in
Google Scholar
PubMed
Close
,
John H Kwon Division of Gastroenterology, Division of Gastroenterology, Division of Gastroenterology, Division of Gastroenterology, Section of Gastroenterology, Department of Surgery, Division of Gastroenterology, Department of Medicine

Search for other papers by John H Kwon in
Google Scholar
PubMed
Close
,
Steven R Brant Division of Gastroenterology, Division of Gastroenterology, Division of Gastroenterology, Division of Gastroenterology, Section of Gastroenterology, Department of Surgery, Division of Gastroenterology, Department of Medicine

Search for other papers by Steven R Brant in
Google Scholar
PubMed
Close
,
Michael R Marohn Division of Gastroenterology, Division of Gastroenterology, Division of Gastroenterology, Division of Gastroenterology, Section of Gastroenterology, Department of Surgery, Division of Gastroenterology, Department of Medicine

Search for other papers by Michael R Marohn in
Google Scholar
PubMed
Close
,
David F Hutcheon Division of Gastroenterology, Division of Gastroenterology, Division of Gastroenterology, Division of Gastroenterology, Section of Gastroenterology, Department of Surgery, Division of Gastroenterology, Department of Medicine

Search for other papers by David F Hutcheon in
Google Scholar
PubMed
Close
,
Mark D Duncan Division of Gastroenterology, Division of Gastroenterology, Division of Gastroenterology, Division of Gastroenterology, Section of Gastroenterology, Department of Surgery, Division of Gastroenterology, Department of Medicine

Search for other papers by Mark D Duncan in
Google Scholar
PubMed
Close
,
Ajay Goel Division of Gastroenterology, Division of Gastroenterology, Division of Gastroenterology, Division of Gastroenterology, Section of Gastroenterology, Department of Surgery, Division of Gastroenterology, Department of Medicine

Search for other papers by Ajay Goel in
Google Scholar
PubMed
Close
, and
Stephen J Meltzer Division of Gastroenterology, Division of Gastroenterology, Division of Gastroenterology, Division of Gastroenterology, Section of Gastroenterology, Department of Surgery, Division of Gastroenterology, Department of Medicine
Division of Gastroenterology, Division of Gastroenterology, Division of Gastroenterology, Division of Gastroenterology, Section of Gastroenterology, Department of Surgery, Division of Gastroenterology, Department of Medicine
Division of Gastroenterology, Division of Gastroenterology, Division of Gastroenterology, Division of Gastroenterology, Section of Gastroenterology, Department of Surgery, Division of Gastroenterology, Department of Medicine

Search for other papers by Stephen J Meltzer in
Google Scholar
PubMed
Close

estrogen receptor α ( ESR1 ; Issa et al . 1994 , Ahuja et al . 1998 ). Association between gender and gene methylation was not assessed due to the small number of female control NC cases studied ( n =2). Evaluation of methylated loci as colonic

Free access