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Audrey Ziverec Cancer Research Centre of Lyon (CRCL), INSERM U1052, CNRS UMR5286, Claude Bernard University, Lyon, France

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Marie Chanal Cancer Research Centre of Lyon (CRCL), INSERM U1052, CNRS UMR5286, Claude Bernard University, Lyon, France

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Perrine Raymond Cancer Research Centre of Lyon (CRCL), INSERM U1052, CNRS UMR5286, Claude Bernard University, Lyon, France

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Mirela Diana Ilie Cancer Research Centre of Lyon (CRCL), INSERM U1052, CNRS UMR5286, Claude Bernard University, Lyon, France
Endocrinology Department, “C.I. Parhon” National Institute of Endocrinology, Bucharest, Romania

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Dario De Alcubierre Cancer Research Centre of Lyon (CRCL), INSERM U1052, CNRS UMR5286, Claude Bernard University, Lyon, France

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Arja Pasternack Department of Physiology, Faculty of Medicine, University of Helsinki, Helsinki, Finland

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Olli Ritvos Department of Physiology, Faculty of Medicine, University of Helsinki, Helsinki, Finland

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Gerald Raverot Cancer Research Centre of Lyon (CRCL), INSERM U1052, CNRS UMR5286, Claude Bernard University, Lyon, France
Faculté de Médecine Lyon Est, Université Lyon 1, Lyon, France
Department of Endocrinology, Reference center for rare pituitary disease (HYPO), Groupement Hospitalier EST, Hospices Civils de Lyon, University of Lyon, Lyon, France

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Philippe Bertolino Cancer Research Centre of Lyon (CRCL), INSERM U1052, CNRS UMR5286, Claude Bernard University, Lyon, France

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available rodent cell models of gonadotroph tumours ( Alarid et al. 1996 ). While αT3 is considered to be an immature gonadotroph cell line based on its lack of hormone expression ( Lim et al. 2007 ), LβT2 cells have been widely used to study gonadotroph

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-22-0245
Volume/Issue:
Volume 30: Issue 3
Restricted access
Toru Tateno Department of Medicine, The Endocrine Oncology Site Group, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada

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Tae Nakano-Tateno Department of Medicine, The Endocrine Oncology Site Group, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada

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Shereen Ezzat Department of Medicine, The Endocrine Oncology Site Group, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada

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Sylvia L Asa Department of Pathology, The Endocrine Oncology Site Group, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada

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36 49 – 59 . ( doi:10.1161/ATVBAHA.115.306074 ) Snyder PJ 1987 Gonadotroph cell pituitary adenomas . Endocrinology and Metabolism Clinics of North America 16 755 – 764 . Stefaneanu L Kovacs K Horvath E Lloyd RV 1991

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-16-0013
Volume/Issue:
Volume 23: Issue 5
Free access
M Principe Cancer Research Centre of Lyon (CRCL), INSERM U1052, CNRS UMR5286, Claude Bernard University, Lyon, France

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M Chanal Cancer Research Centre of Lyon (CRCL), INSERM U1052, CNRS UMR5286, Claude Bernard University, Lyon, France

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V Karam Cancer Research Centre of Lyon (CRCL), INSERM U1052, CNRS UMR5286, Claude Bernard University, Lyon, France

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A Wierinckx Cancer Research Centre of Lyon (CRCL), INSERM U1052, CNRS UMR5286, Claude Bernard University, Lyon, France
ProfilXpert, Lyon, France

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I Mikaélian Cancer Research Centre of Lyon (CRCL), INSERM U1052, CNRS UMR5286, Claude Bernard University, Lyon, France

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R Gadet Cancer Research Centre of Lyon (CRCL), INSERM U1052, CNRS UMR5286, Claude Bernard University, Lyon, France

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C Auger Cancer Research Centre of Lyon (CRCL), INSERM U1052, CNRS UMR5286, Claude Bernard University, Lyon, France

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V Raverot Laboratoire d’Hormonologie, Centre de Biologie et de Pathologie Est, Hospices Civils de Lyon, Lyon, France

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E Jouanneau Service de Neurochirurgie, Groupement Hospitalier Est, Hospices Civils de Lyon, Bron, France
Faculté de Médecine Lyon Est, Université Lyon 1, Lyon, France

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A Vasiljevic Faculté de Médecine Lyon Est, Université Lyon 1, Lyon, France
Department of Pathology, Groupement Hospitalier EST, Hospices Civils de Lyon, University of Lyon, Lyon, France

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A Hennino Cancer Research Centre of Lyon (CRCL), INSERM U1052, CNRS UMR5286, Claude Bernard University, Lyon, France

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G Raverot Cancer Research Centre of Lyon (CRCL), INSERM U1052, CNRS UMR5286, Claude Bernard University, Lyon, France
Department of Pathology, Groupement Hospitalier EST, Hospices Civils de Lyon, University of Lyon, Lyon, France
Department of Endocrinology, Reference Center for Rare Pituitary Disease (HYPO), Groupement Hospitalier EST, Hospices Civils de Lyon, University of Lyon, Lyon, France

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P Bertolino Cancer Research Centre of Lyon (CRCL), INSERM U1052, CNRS UMR5286, Claude Bernard University, Lyon, France

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areas (Supplementary Fig. 1). Interestingly, ALK7 expression was shown to be restricted to FSH-producing gonadotroph cells in the pituitary gland of WT mice ( Sandoval-Guzman et al . 2012 ). Based on this observation, we questioned whether the

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-18-0082
Volume/Issue:
Volume 25: Issue 9
Free access
Iain R Thompson Endocrine Signalling Group, Developmental Biology Research Group, Department of Endocrinology, Neuropathology Department, Department of Endocrinology, School of Medicine, Department of Medicine, Medical Research Council Human Reproductive Sciences Unit, Veterinary Basic Sciences

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Annisa N Chand Endocrine Signalling Group, Developmental Biology Research Group, Department of Endocrinology, Neuropathology Department, Department of Endocrinology, School of Medicine, Department of Medicine, Medical Research Council Human Reproductive Sciences Unit, Veterinary Basic Sciences

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Peter J King Endocrine Signalling Group, Developmental Biology Research Group, Department of Endocrinology, Neuropathology Department, Department of Endocrinology, School of Medicine, Department of Medicine, Medical Research Council Human Reproductive Sciences Unit, Veterinary Basic Sciences

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Olaf Ansorge Endocrine Signalling Group, Developmental Biology Research Group, Department of Endocrinology, Neuropathology Department, Department of Endocrinology, School of Medicine, Department of Medicine, Medical Research Council Human Reproductive Sciences Unit, Veterinary Basic Sciences

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Niki Karavitaki Endocrine Signalling Group, Developmental Biology Research Group, Department of Endocrinology, Neuropathology Department, Department of Endocrinology, School of Medicine, Department of Medicine, Medical Research Council Human Reproductive Sciences Unit, Veterinary Basic Sciences

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Ceri Alexander Jones Endocrine Signalling Group, Developmental Biology Research Group, Department of Endocrinology, Neuropathology Department, Department of Endocrinology, School of Medicine, Department of Medicine, Medical Research Council Human Reproductive Sciences Unit, Veterinary Basic Sciences

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Dolkun Rahmutula Endocrine Signalling Group, Developmental Biology Research Group, Department of Endocrinology, Neuropathology Department, Department of Endocrinology, School of Medicine, Department of Medicine, Medical Research Council Human Reproductive Sciences Unit, Veterinary Basic Sciences

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David G Gardner Endocrine Signalling Group, Developmental Biology Research Group, Department of Endocrinology, Neuropathology Department, Department of Endocrinology, School of Medicine, Department of Medicine, Medical Research Council Human Reproductive Sciences Unit, Veterinary Basic Sciences

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Vladimir Zivkovic Endocrine Signalling Group, Developmental Biology Research Group, Department of Endocrinology, Neuropathology Department, Department of Endocrinology, School of Medicine, Department of Medicine, Medical Research Council Human Reproductive Sciences Unit, Veterinary Basic Sciences

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Caroline P Wheeler-Jones Endocrine Signalling Group, Developmental Biology Research Group, Department of Endocrinology, Neuropathology Department, Department of Endocrinology, School of Medicine, Department of Medicine, Medical Research Council Human Reproductive Sciences Unit, Veterinary Basic Sciences

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Imelda M McGonnell Endocrine Signalling Group, Developmental Biology Research Group, Department of Endocrinology, Neuropathology Department, Department of Endocrinology, School of Medicine, Department of Medicine, Medical Research Council Human Reproductive Sciences Unit, Veterinary Basic Sciences

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Márta Korbonits Endocrine Signalling Group, Developmental Biology Research Group, Department of Endocrinology, Neuropathology Department, Department of Endocrinology, School of Medicine, Department of Medicine, Medical Research Council Human Reproductive Sciences Unit, Veterinary Basic Sciences

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Richard A Anderson Endocrine Signalling Group, Developmental Biology Research Group, Department of Endocrinology, Neuropathology Department, Department of Endocrinology, School of Medicine, Department of Medicine, Medical Research Council Human Reproductive Sciences Unit, Veterinary Basic Sciences

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John A H Wass Endocrine Signalling Group, Developmental Biology Research Group, Department of Endocrinology, Neuropathology Department, Department of Endocrinology, School of Medicine, Department of Medicine, Medical Research Council Human Reproductive Sciences Unit, Veterinary Basic Sciences

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Alan S McNeilly Endocrine Signalling Group, Developmental Biology Research Group, Department of Endocrinology, Neuropathology Department, Department of Endocrinology, School of Medicine, Department of Medicine, Medical Research Council Human Reproductive Sciences Unit, Veterinary Basic Sciences

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Robert C Fowkes Endocrine Signalling Group, Developmental Biology Research Group, Department of Endocrinology, Neuropathology Department, Department of Endocrinology, School of Medicine, Department of Medicine, Medical Research Council Human Reproductive Sciences Unit, Veterinary Basic Sciences

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gonadotroph cell lines of different developmental origin expressed most components of an intact natriuretic peptide system ( Thompson et al . 2009 ), we initially examined a series of normal human fetal pituitary samples for the expression of NPR2 and NPPC

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-12-0129
Volume/Issue:
Volume 19: Issue 4
Free access
Odelia Cooper
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George Vlotides Department of Medicine, Department of Medicine II, Department of Biomedical Science and Pathology and Laboratory Medicine, Department of Pathology and Laboratory Medicine, Pituitary Center, Cedars-Sinai Medical Center, Academic Affairs, Room 2015, 8700 Beverly Boulevard, Los Angeles, California 90048, USA

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Hidenori Fukuoka
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Mark I Greene Department of Medicine, Department of Medicine II, Department of Biomedical Science and Pathology and Laboratory Medicine, Department of Pathology and Laboratory Medicine, Pituitary Center, Cedars-Sinai Medical Center, Academic Affairs, Room 2015, 8700 Beverly Boulevard, Los Angeles, California 90048, USA
Department of Medicine, Department of Medicine II, Department of Biomedical Science and Pathology and Laboratory Medicine, Department of Pathology and Laboratory Medicine, Pituitary Center, Cedars-Sinai Medical Center, Academic Affairs, Room 2015, 8700 Beverly Boulevard, Los Angeles, California 90048, USA

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Shlomo Melmed
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direct and paracrine fashion. Further studies remain to determine the role of ErbB receptors in corticotroph tumor development and behavior. Gonadotroph cells EGFR ligands and receptor Double immunostaining for EGF protein with pituitary hormones

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-11-0066
Volume/Issue:
Volume 18: Issue 6
Free access
Elena Sabini Department of Pathology, Johns Hopkins Hospital, School of Medicine, Baltimore, Maryland, USA
Department of Pathology, Johns Hopkins Hospital, School of Medicine, Baltimore, Maryland, USA

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Amna Khan Department of Pathology, Johns Hopkins Hospital, School of Medicine, Baltimore, Maryland, USA
Department of Pathology, Johns Hopkins Hospital, School of Medicine, Baltimore, Maryland, USA

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Patrizio Caturegli Department of Pathology, Johns Hopkins Hospital, School of Medicine, Baltimore, Maryland, USA
Department of Pathology, Johns Hopkins Hospital, School of Medicine, Baltimore, Maryland, USA

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Five rodent pituitary cell lines were used: TαT1, LβT2, AtT-20 (CCL-89), GH3 (CCL-82.1), and MMQ (CRL-10609). The first two lines were a kind gift from Dr Pamela L Mellon; the last three lines were purchased from ATCC. LβT2, a mouse gonadotroph cell

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-23-0196
Volume/Issue:
Volume 31: Issue 1
Restricted access
Dario Palmieri Dipartimento di Biologia e Patologia Cellulare e Molecolare, Dipartimento di Scienze Neurologiche, INSERM U1028; CNRS UMR5292; Lyon Neuroscience Research Center, University Lyon1, Dipartimento di Endocrinologia

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Teresa Valentino Dipartimento di Biologia e Patologia Cellulare e Molecolare, Dipartimento di Scienze Neurologiche, INSERM U1028; CNRS UMR5292; Lyon Neuroscience Research Center, University Lyon1, Dipartimento di Endocrinologia

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Ivana De Martino Dipartimento di Biologia e Patologia Cellulare e Molecolare, Dipartimento di Scienze Neurologiche, INSERM U1028; CNRS UMR5292; Lyon Neuroscience Research Center, University Lyon1, Dipartimento di Endocrinologia

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Francesco Esposito Dipartimento di Biologia e Patologia Cellulare e Molecolare, Dipartimento di Scienze Neurologiche, INSERM U1028; CNRS UMR5292; Lyon Neuroscience Research Center, University Lyon1, Dipartimento di Endocrinologia

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Paolo Cappabianca Dipartimento di Biologia e Patologia Cellulare e Molecolare, Dipartimento di Scienze Neurologiche, INSERM U1028; CNRS UMR5292; Lyon Neuroscience Research Center, University Lyon1, Dipartimento di Endocrinologia

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Anne Wierinckx Dipartimento di Biologia e Patologia Cellulare e Molecolare, Dipartimento di Scienze Neurologiche, INSERM U1028; CNRS UMR5292; Lyon Neuroscience Research Center, University Lyon1, Dipartimento di Endocrinologia
Dipartimento di Biologia e Patologia Cellulare e Molecolare, Dipartimento di Scienze Neurologiche, INSERM U1028; CNRS UMR5292; Lyon Neuroscience Research Center, University Lyon1, Dipartimento di Endocrinologia

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Michela Vitiello Dipartimento di Biologia e Patologia Cellulare e Molecolare, Dipartimento di Scienze Neurologiche, INSERM U1028; CNRS UMR5292; Lyon Neuroscience Research Center, University Lyon1, Dipartimento di Endocrinologia

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Gaetano Lombardi Dipartimento di Biologia e Patologia Cellulare e Molecolare, Dipartimento di Scienze Neurologiche, INSERM U1028; CNRS UMR5292; Lyon Neuroscience Research Center, University Lyon1, Dipartimento di Endocrinologia

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Annamaria Colao Dipartimento di Biologia e Patologia Cellulare e Molecolare, Dipartimento di Scienze Neurologiche, INSERM U1028; CNRS UMR5292; Lyon Neuroscience Research Center, University Lyon1, Dipartimento di Endocrinologia

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Jacqueline Trouillas Dipartimento di Biologia e Patologia Cellulare e Molecolare, Dipartimento di Scienze Neurologiche, INSERM U1028; CNRS UMR5292; Lyon Neuroscience Research Center, University Lyon1, Dipartimento di Endocrinologia
Dipartimento di Biologia e Patologia Cellulare e Molecolare, Dipartimento di Scienze Neurologiche, INSERM U1028; CNRS UMR5292; Lyon Neuroscience Research Center, University Lyon1, Dipartimento di Endocrinologia

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Giovanna Maria Pierantoni Dipartimento di Biologia e Patologia Cellulare e Molecolare, Dipartimento di Scienze Neurologiche, INSERM U1028; CNRS UMR5292; Lyon Neuroscience Research Center, University Lyon1, Dipartimento di Endocrinologia

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Alfredo Fusco Dipartimento di Biologia e Patologia Cellulare e Molecolare, Dipartimento di Scienze Neurologiche, INSERM U1028; CNRS UMR5292; Lyon Neuroscience Research Center, University Lyon1, Dipartimento di Endocrinologia

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Monica Fedele Dipartimento di Biologia e Patologia Cellulare e Molecolare, Dipartimento di Scienze Neurologiche, INSERM U1028; CNRS UMR5292; Lyon Neuroscience Research Center, University Lyon1, Dipartimento di Endocrinologia

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as the mouse gonadotroph cell line αT3. Indeed, as shown in Fig. 4 B, Pit1 overexpression caused a twofold increase in the number of colonies with respect to the backbone vector. Since αT3 cells do not express Pit1 normally, we asked whether the

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-11-0135
Volume/Issue:
Volume 19: Issue 2
Free access
Françoise Galland Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France
Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France

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Ludovic Lacroix Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France
Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France

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Patrick Saulnier Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France

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Philippe Dessen Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France
Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France

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Geri Meduri Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France
Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France
Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France

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Michèle Bernier Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France

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Stéphane Gaillard Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France

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Jean Guibourdenche Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France
Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France

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Thierry Fournier Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France

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Danièle Evain-Brion Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France
Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France

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Jean Michel Bidart Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France
Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France

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Philippe Chanson Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France
Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France
Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale, Institut de Cancérologie Gustave-Roussy, Centre National de la Recherche Scientifique, Département de Génomique Fonctionnelle, Assistance Publique-Hôpitaux de Paris, Hôpital Foch, Service de Neurochirurgie, Institut National de la Santé et de la Recherche Médicale, Université Paris-Sud 11, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Le Kremlin-Bicêtre F-94275, France

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features. Most NFPAs are gonadotroph adenomas expressing steroidogenic factor 1 ( Asa et al . 1996 , Al-Shraim & Asa 2006 ), required for differentiation of gonadotroph cells, and producing follicle-stimulating hormone (FSH)β and/or luteinizing hormone

Article Type:
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DOI:
https://doi.org/10.1677/ERC-10-0018
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Volume 17: Issue 2
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Maria Eugenia Sabatino
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Juan Pablo Petiti
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Liliana del Valle Sosa
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Pablo Anibal Pérez
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Silvina Gutiérrez
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Carolina Leimgruber
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Alexandra Latini Facultad de Ciencias Médicas, Laboratorio de Bioenergética y Estrés Oxidativo, Instituto de Investigaciones en Ciencias de la Salud (INICSA–CONICET), Centro de Microscopía Electrónica, Universidad Nacional de Córdoba, Av. Enrique Barros y Enfermera Gordillo, Ciudad Universitaria, 5000 Córdoba, Argentina

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Alicia Inés Torres
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Ana Lucía De Paul
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reasons. Firstly, alpha and beta estrogen receptors are also present in folliculostellate ( Mitchner et al . 1998 ), somatotroph, thyrotroph, and gonadotroph cells ( Nishihara et al . 2000 , Gonzalez et al . 2008 ). Also, compelling reports by Nolan

Article Type:
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https://doi.org/10.1530/ERC-14-0333
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Volume 22: Issue 3
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Maria Chiara Zatelli
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Daniela Piccin
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Cristina Vignali
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Federico Tagliati
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Maria Rosaria Ambrosio
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Marta Bondanelli
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Vincenzo Cimino
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Antonio Bianchi
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Herbert A Schmid
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Massimo Scanarini
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Alfredo Pontecorvi
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Laura De Marinis
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Giulio Maira
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Ettore C degli Uberti
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were undetectable in the other 17 tumors. Therefore, these adenomas were histologically diagnosed as gonadotroph cell adenoma or null cell adenoma. Human total RNA from normal pituitary was used as a control for RT-PCRs (Analytical Biological Services

Article Type:
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DOI:
https://doi.org/10.1677/ERC-06-0026
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