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Gahee Park Samsung Genome Institute, Internal Medicine, Surgery, Biomedical Sciences, Department of Internal Medicine, Department of Molecular Cell Biology, Samsung Medical Center, 50 Irwondong, Gangnamgu, Seoul 135-710, Korea Departments of
Samsung Genome Institute, Internal Medicine, Surgery, Biomedical Sciences, Department of Internal Medicine, Department of Molecular Cell Biology, Samsung Medical Center, 50 Irwondong, Gangnamgu, Seoul 135-710, Korea Departments of

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Tae Hyuk Kim Samsung Genome Institute, Internal Medicine, Surgery, Biomedical Sciences, Department of Internal Medicine, Department of Molecular Cell Biology, Samsung Medical Center, 50 Irwondong, Gangnamgu, Seoul 135-710, Korea Departments of

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Hae-Ock Lee Samsung Genome Institute, Internal Medicine, Surgery, Biomedical Sciences, Department of Internal Medicine, Department of Molecular Cell Biology, Samsung Medical Center, 50 Irwondong, Gangnamgu, Seoul 135-710, Korea Departments of

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Jung Ah Lim Samsung Genome Institute, Internal Medicine, Surgery, Biomedical Sciences, Department of Internal Medicine, Department of Molecular Cell Biology, Samsung Medical Center, 50 Irwondong, Gangnamgu, Seoul 135-710, Korea Departments of
Samsung Genome Institute, Internal Medicine, Surgery, Biomedical Sciences, Department of Internal Medicine, Department of Molecular Cell Biology, Samsung Medical Center, 50 Irwondong, Gangnamgu, Seoul 135-710, Korea Departments of

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Jae-Kyung Won Samsung Genome Institute, Internal Medicine, Surgery, Biomedical Sciences, Department of Internal Medicine, Department of Molecular Cell Biology, Samsung Medical Center, 50 Irwondong, Gangnamgu, Seoul 135-710, Korea Departments of

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Hye Sook Min Samsung Genome Institute, Internal Medicine, Surgery, Biomedical Sciences, Department of Internal Medicine, Department of Molecular Cell Biology, Samsung Medical Center, 50 Irwondong, Gangnamgu, Seoul 135-710, Korea Departments of

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Kyu Eun Lee Samsung Genome Institute, Internal Medicine, Surgery, Biomedical Sciences, Department of Internal Medicine, Department of Molecular Cell Biology, Samsung Medical Center, 50 Irwondong, Gangnamgu, Seoul 135-710, Korea Departments of

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Do Joon Park Samsung Genome Institute, Internal Medicine, Surgery, Biomedical Sciences, Department of Internal Medicine, Department of Molecular Cell Biology, Samsung Medical Center, 50 Irwondong, Gangnamgu, Seoul 135-710, Korea Departments of

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Young Joo Park Samsung Genome Institute, Internal Medicine, Surgery, Biomedical Sciences, Department of Internal Medicine, Department of Molecular Cell Biology, Samsung Medical Center, 50 Irwondong, Gangnamgu, Seoul 135-710, Korea Departments of

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Woong-Yang Park Samsung Genome Institute, Internal Medicine, Surgery, Biomedical Sciences, Department of Internal Medicine, Department of Molecular Cell Biology, Samsung Medical Center, 50 Irwondong, Gangnamgu, Seoul 135-710, Korea Departments of
Samsung Genome Institute, Internal Medicine, Surgery, Biomedical Sciences, Department of Internal Medicine, Department of Molecular Cell Biology, Samsung Medical Center, 50 Irwondong, Gangnamgu, Seoul 135-710, Korea Departments of
Samsung Genome Institute, Internal Medicine, Surgery, Biomedical Sciences, Department of Internal Medicine, Department of Molecular Cell Biology, Samsung Medical Center, 50 Irwondong, Gangnamgu, Seoul 135-710, Korea Departments of

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evaluated first. More importantly, a practical diagnostic assay for identifying rearrangements of ALK in thyroid cancer is essential. As is the case with non-small cell lung cancer (NSCLC), immunohistochemistry (IHC) may be a useful tool for screening for

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Ziwei Zhang Department of Endocrinology, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China
Department of Endocrinology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China

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Menglian Li Department of Endocrinology, Nanjing Drum Tower Hospital Clinical College of Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China

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Jianjun Wang Department of Pathology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China

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Mengsi Liu Department of Endocrinology, Nanjing Drum Tower Hospital, Chinese Academy of Medical Science & Graduate School of Peking Union Medical College, Nanjing, China

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Huan Chen Department of Endocrinology, Nanjing Drum Tower Hospital, Chinese Academy of Medical Science & Graduate School of Peking Union Medical College, Nanjing, China

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Yuan Lou Department of Endocrinology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China

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Yijie Wang Department of Endocrinology, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China

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Qi Sun Department of Pathology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China

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Dalong Zhu Department of Endocrinology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China

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Ping Li Department of Endocrinology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China

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Yan Bi Department of Endocrinology, Nanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China
Department of Endocrinology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, China

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contrast, Fay et al. (2015) employed immunohistochemistry to show PD-L1 expression in only 11% of ACC cases; overall, the expression of PD-L1 did not correlate with tumor stage, excessive hormone secretion or 5-year survival rate. Despite these

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Takuya Mikoshiba Department of Otolaryngology, Head and Neck Surgery, Keio University School of Medicine, Shinanomachi, Shinjuku-ku, Tokyo, Japan

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Mariko Sekimizu Department of Otolaryngology, Head and Neck Surgery, Keio University School of Medicine, Shinanomachi, Shinjuku-ku, Tokyo, Japan

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Shin Saito Department of Otolaryngology, Head and Neck Surgery, Keio University School of Medicine, Shinanomachi, Shinjuku-ku, Tokyo, Japan

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Shintaro Nakamura Department of Otolaryngology, Head and Neck Surgery, Keio University School of Medicine, Shinanomachi, Shinjuku-ku, Tokyo, Japan

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Ryoto Nagai Department of Otolaryngology, Head and Neck Surgery, Keio University School of Medicine, Shinanomachi, Shinjuku-ku, Tokyo, Japan

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Miho Kawaida Division of Diagnostic Pathology, Keio University Hospital, Shinanomachi, Shinjuku-ku, Tokyo, Japan

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Isao Kurihara Division of Medical Education Improvement and Planning, Medical Education and Clinical Training Center, National Defense Medical College, Namiki, Tokorozawa, Saitama, Japan
Department of Endocrinology, Metabolism and Nephrology, Keio University School of Medicine, Shinanomachi, Shinjuku-ku, Tokyo, Japan

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Sakiko Kobayashi Department of Endocrinology, Metabolism and Nephrology, Keio University School of Medicine, Shinanomachi, Shinjuku-ku, Tokyo, Japan
Department of Endocrinology, Metabolism and Nephrology, NHO Tokyo Medical Center, Higashigaoka, Meguro-ku, Tokyo, Japan

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Hiroyuki Ozawa Department of Otolaryngology, Head and Neck Surgery, Keio University School of Medicine, Shinanomachi, Shinjuku-ku, Tokyo, Japan

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et al. 1988 ). Immunohistochemistry Immunohistochemistry for ACTH was performed on tumor samples from 15 patients with ONB to evaluate whether the tumor cells expressed ACTH. Surgically resected recurrent and metastatic tumors were also

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Noriko Kimura
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Ryoichi Takayanagi Pathology Division, Department of Medicine and Bioregulatory Science, Department of Urology and Andrology, Third Department of Internal Medicine (Diabetes Endocrine and Metabolism), Department of Medicine, Department of Urology, Department of Geriatric Medicine and Nephrology, Division of Nephrology, Department of Endocrinology and Metabolism, Department of Endocrinology and Metabolism, Division of Nephrology, Council Member Examination Committee of Social Insurance, Department of Endocrinology, Department of Clinical Research, National Hospital Organization, Hakodate Hospital, Postal cord 041-8512, 18-16 Kawahara, Hakodate, Hokkaido, Japan

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Nae Takizawa Pathology Division, Department of Medicine and Bioregulatory Science, Department of Urology and Andrology, Third Department of Internal Medicine (Diabetes Endocrine and Metabolism), Department of Medicine, Department of Urology, Department of Geriatric Medicine and Nephrology, Division of Nephrology, Department of Endocrinology and Metabolism, Department of Endocrinology and Metabolism, Division of Nephrology, Council Member Examination Committee of Social Insurance, Department of Endocrinology, Department of Clinical Research, National Hospital Organization, Hakodate Hospital, Postal cord 041-8512, 18-16 Kawahara, Hakodate, Hokkaido, Japan

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Eiji Itagaki Pathology Division, Department of Medicine and Bioregulatory Science, Department of Urology and Andrology, Third Department of Internal Medicine (Diabetes Endocrine and Metabolism), Department of Medicine, Department of Urology, Department of Geriatric Medicine and Nephrology, Division of Nephrology, Department of Endocrinology and Metabolism, Department of Endocrinology and Metabolism, Division of Nephrology, Council Member Examination Committee of Social Insurance, Department of Endocrinology, Department of Clinical Research, National Hospital Organization, Hakodate Hospital, Postal cord 041-8512, 18-16 Kawahara, Hakodate, Hokkaido, Japan

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Takayuki Katabami Pathology Division, Department of Medicine and Bioregulatory Science, Department of Urology and Andrology, Third Department of Internal Medicine (Diabetes Endocrine and Metabolism), Department of Medicine, Department of Urology, Department of Geriatric Medicine and Nephrology, Division of Nephrology, Department of Endocrinology and Metabolism, Department of Endocrinology and Metabolism, Division of Nephrology, Council Member Examination Committee of Social Insurance, Department of Endocrinology, Department of Clinical Research, National Hospital Organization, Hakodate Hospital, Postal cord 041-8512, 18-16 Kawahara, Hakodate, Hokkaido, Japan

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Narihiko Kakoi Pathology Division, Department of Medicine and Bioregulatory Science, Department of Urology and Andrology, Third Department of Internal Medicine (Diabetes Endocrine and Metabolism), Department of Medicine, Department of Urology, Department of Geriatric Medicine and Nephrology, Division of Nephrology, Department of Endocrinology and Metabolism, Department of Endocrinology and Metabolism, Division of Nephrology, Council Member Examination Committee of Social Insurance, Department of Endocrinology, Department of Clinical Research, National Hospital Organization, Hakodate Hospital, Postal cord 041-8512, 18-16 Kawahara, Hakodate, Hokkaido, Japan

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Hiromi Rakugi Pathology Division, Department of Medicine and Bioregulatory Science, Department of Urology and Andrology, Third Department of Internal Medicine (Diabetes Endocrine and Metabolism), Department of Medicine, Department of Urology, Department of Geriatric Medicine and Nephrology, Division of Nephrology, Department of Endocrinology and Metabolism, Department of Endocrinology and Metabolism, Division of Nephrology, Council Member Examination Committee of Social Insurance, Department of Endocrinology, Department of Clinical Research, National Hospital Organization, Hakodate Hospital, Postal cord 041-8512, 18-16 Kawahara, Hakodate, Hokkaido, Japan

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Yukihiro Ikeda Pathology Division, Department of Medicine and Bioregulatory Science, Department of Urology and Andrology, Third Department of Internal Medicine (Diabetes Endocrine and Metabolism), Department of Medicine, Department of Urology, Department of Geriatric Medicine and Nephrology, Division of Nephrology, Department of Endocrinology and Metabolism, Department of Endocrinology and Metabolism, Division of Nephrology, Council Member Examination Committee of Social Insurance, Department of Endocrinology, Department of Clinical Research, National Hospital Organization, Hakodate Hospital, Postal cord 041-8512, 18-16 Kawahara, Hakodate, Hokkaido, Japan

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Akiyo Tanabe Pathology Division, Department of Medicine and Bioregulatory Science, Department of Urology and Andrology, Third Department of Internal Medicine (Diabetes Endocrine and Metabolism), Department of Medicine, Department of Urology, Department of Geriatric Medicine and Nephrology, Division of Nephrology, Department of Endocrinology and Metabolism, Department of Endocrinology and Metabolism, Division of Nephrology, Council Member Examination Committee of Social Insurance, Department of Endocrinology, Department of Clinical Research, National Hospital Organization, Hakodate Hospital, Postal cord 041-8512, 18-16 Kawahara, Hakodate, Hokkaido, Japan

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Takeshi Nigawara Pathology Division, Department of Medicine and Bioregulatory Science, Department of Urology and Andrology, Third Department of Internal Medicine (Diabetes Endocrine and Metabolism), Department of Medicine, Department of Urology, Department of Geriatric Medicine and Nephrology, Division of Nephrology, Department of Endocrinology and Metabolism, Department of Endocrinology and Metabolism, Division of Nephrology, Council Member Examination Committee of Social Insurance, Department of Endocrinology, Department of Clinical Research, National Hospital Organization, Hakodate Hospital, Postal cord 041-8512, 18-16 Kawahara, Hakodate, Hokkaido, Japan

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Sadayoshi Ito Pathology Division, Department of Medicine and Bioregulatory Science, Department of Urology and Andrology, Third Department of Internal Medicine (Diabetes Endocrine and Metabolism), Department of Medicine, Department of Urology, Department of Geriatric Medicine and Nephrology, Division of Nephrology, Department of Endocrinology and Metabolism, Department of Endocrinology and Metabolism, Division of Nephrology, Council Member Examination Committee of Social Insurance, Department of Endocrinology, Department of Clinical Research, National Hospital Organization, Hakodate Hospital, Postal cord 041-8512, 18-16 Kawahara, Hakodate, Hokkaido, Japan

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Itaru Kimura Pathology Division, Department of Medicine and Bioregulatory Science, Department of Urology and Andrology, Third Department of Internal Medicine (Diabetes Endocrine and Metabolism), Department of Medicine, Department of Urology, Department of Geriatric Medicine and Nephrology, Division of Nephrology, Department of Endocrinology and Metabolism, Department of Endocrinology and Metabolism, Division of Nephrology, Council Member Examination Committee of Social Insurance, Department of Endocrinology, Department of Clinical Research, National Hospital Organization, Hakodate Hospital, Postal cord 041-8512, 18-16 Kawahara, Hakodate, Hokkaido, Japan

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Mitsuhide Naruse Pathology Division, Department of Medicine and Bioregulatory Science, Department of Urology and Andrology, Third Department of Internal Medicine (Diabetes Endocrine and Metabolism), Department of Medicine, Department of Urology, Department of Geriatric Medicine and Nephrology, Division of Nephrology, Department of Endocrinology and Metabolism, Department of Endocrinology and Metabolism, Division of Nephrology, Council Member Examination Committee of Social Insurance, Department of Endocrinology, Department of Clinical Research, National Hospital Organization, Hakodate Hospital, Postal cord 041-8512, 18-16 Kawahara, Hakodate, Hokkaido, Japan

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The Phaeochromocytoma Study Group in Japan
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immunohistochemistry to facilitate the differential diagnosis of malignant from benign disease in PHEO/PGL. Subjects and methods Patients and tissues A total of 994 patients from 178 institutes registered online. For ethical reasons, the registration was limited to

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Maria Cristina De Martino
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Richard A Feelders
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Wouter W de Herder
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Peter M van Koetsveld
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Fadime Dogan
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Joseph A M J L Janssen
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A Marlijn Waaijers
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Claudia Pivonello Department of Internal Medicine Division of Endocrinology, Erasmus Medical Center, Rotterdam, The Netherlands

Dipartimento di Medicina Clinica e Chirurgia Sezione di Endocrinologia, Università Federico II, Naples, Italy

Department of Pathology Erasmus Medical Center, Rotterdam and Reinier de Graaf Gasthuis, Delft, The Netherlands

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Steven W J Lamberts
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Annamaria Colao Department of Internal Medicine Division of Endocrinology, Erasmus Medical Center, Rotterdam, The Netherlands

Dipartimento di Medicina Clinica e Chirurgia Sezione di Endocrinologia, Università Federico II, Naples, Italy

Department of Pathology Erasmus Medical Center, Rotterdam and Reinier de Graaf Gasthuis, Delft, The Netherlands

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Ronald R de Krijger Department of Internal Medicine Division of Endocrinology, Erasmus Medical Center, Rotterdam, The Netherlands

Dipartimento di Medicina Clinica e Chirurgia Sezione di Endocrinologia, Università Federico II, Naples, Italy

Department of Pathology Erasmus Medical Center, Rotterdam and Reinier de Graaf Gasthuis, Delft, The Netherlands

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Rosario Pivonello Department of Internal Medicine Division of Endocrinology, Erasmus Medical Center, Rotterdam, The Netherlands

Dipartimento di Medicina Clinica e Chirurgia Sezione di Endocrinologia, Università Federico II, Naples, Italy

Department of Pathology Erasmus Medical Center, Rotterdam and Reinier de Graaf Gasthuis, Delft, The Netherlands

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Leo J Hofland
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threshold method, 2−ΔCt ( Schmittgen & Livak 2008 ), after efficiency correction ( Pfaffl 2001 ) of target and reference gene transcripts ( HPRT ). Immunohistochemistry The expression of total/phospho-mTOR, total/phospho-4EBP1, and total/phospho-S6K1 in

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Anela Blažević Department of Internal Medicine, Section Endocrinology, Erasmus University Medical Center and Erasmus MC Cancer Institute, Rotterdam, The Netherlands

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Anand M Iyer Department of Internal Medicine, Section Endocrinology, Erasmus University Medical Center and Erasmus MC Cancer Institute, Rotterdam, The Netherlands

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Marie-Louise F van Velthuysen Department of Pathology, Erasmus University Medical Center and Erasmus MC Cancer Institute, Rotterdam, The Netherlands

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Johannes Hofland Department of Internal Medicine, Section Endocrinology, Erasmus University Medical Center and Erasmus MC Cancer Institute, Rotterdam, The Netherlands

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Gaston J H Franssen Department of Surgery, Erasmus University Medical Center and Erasmus MC Cancer Institute, Rotterdam, The Netherlands

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Richard A Feelders Department of Internal Medicine, Section Endocrinology, Erasmus University Medical Center and Erasmus MC Cancer Institute, Rotterdam, The Netherlands

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Marina Zajec Laboratory of Neuro-Oncology/Clinical & Cancer Proteomics, Department of Neurology, Erasmus University Medical Center and Erasmus MC Cancer Institute, Rotterdam, The Netherlands

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Theo M Luider Laboratory of Neuro-Oncology/Clinical & Cancer Proteomics, Department of Neurology, Erasmus University Medical Center and Erasmus MC Cancer Institute, Rotterdam, The Netherlands

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Wouter W de Herder Department of Internal Medicine, Section Endocrinology, Erasmus University Medical Center and Erasmus MC Cancer Institute, Rotterdam, The Netherlands

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Leo J Hofland Department of Internal Medicine, Section Endocrinology, Erasmus University Medical Center and Erasmus MC Cancer Institute, Rotterdam, The Netherlands

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% FDR at the peptide level. FDRs were estimated by inclusion of a decoy database search generated by Mascot. A Protein Report exported from Scaffold was used for data analysis. Immunohistochemistry Immunohistochemistry (IHC) was performed for

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Sylvia L Asa Pathology, University Hospitals Cleveland Medical Center, Case Western Reserve University, Cleveland, Ohio, USA

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Shereen Ezzat Medicine, University Health Network, University of Toronto, Toronto, Ontario, Canada

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ligands (SRL). We find it fascinating that new complex technologies such as molecular profiling are confirming data that was published many years ago using routine immunohistochemistry. In 2002 and 2004, our Japanese colleagues led by Dr Toshiaki Sano

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Arthur S Tischler Department of Pathology and Laboratory Medicine, Department of Pathology, Department of Pathology, Tufts Medical Center, Tufts University School of Medicine, 800 Washington Street, Box 802, Boston, Massachusetts 02111, USA

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Ronald R deKrijger Department of Pathology and Laboratory Medicine, Department of Pathology, Department of Pathology, Tufts Medical Center, Tufts University School of Medicine, 800 Washington Street, Box 802, Boston, Massachusetts 02111, USA
Department of Pathology and Laboratory Medicine, Department of Pathology, Department of Pathology, Tufts Medical Center, Tufts University School of Medicine, 800 Washington Street, Box 802, Boston, Massachusetts 02111, USA

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). Immunohistochemistry is used as an aid to diagnosis in challenging cases, with the immunohistochemical markers tailored to both the anatomic site and the diagnoses under consideration. As general guidelines, pheochromocytomas and paragangliomas express generic

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Maria Eugenia Sabatino
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Juan Pablo Petiti
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Liliana del Valle Sosa
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Pablo Anibal Pérez
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Silvina Gutiérrez
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Carolina Leimgruber
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Alexandra Latini Facultad de Ciencias Médicas, Laboratorio de Bioenergética y Estrés Oxidativo, Instituto de Investigaciones en Ciencias de la Salud (INICSA–CONICET), Centro de Microscopía Electrónica, Universidad Nacional de Córdoba, Av. Enrique Barros y Enfermera Gordillo, Ciudad Universitaria, 5000 Córdoba, Argentina

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Alicia Inés Torres
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Ana Lucía De Paul
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-006-0101-9 ). 16823503 Nishihara E Nagayama Y Inoue S Hiroi H Muramatsu M Yamashita S Koji T 2000 Ontogenetic changes in the expression of estrogen receptor α and β in rat pituitary gland detected by immunohistochemistry . Endocrinology 141 615

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P S H Soon Cancer Genetics, Department of Surgery, Anatomical Pathology, Endocrinology, Endocrine and Oncology Surgery, Kolling Institute of Medical Research, Royal North Shore Hospital, University of Sydney, St Leonards, Sydney, New South Wales 2065, Australia
Cancer Genetics, Department of Surgery, Anatomical Pathology, Endocrinology, Endocrine and Oncology Surgery, Kolling Institute of Medical Research, Royal North Shore Hospital, University of Sydney, St Leonards, Sydney, New South Wales 2065, Australia

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A J Gill Cancer Genetics, Department of Surgery, Anatomical Pathology, Endocrinology, Endocrine and Oncology Surgery, Kolling Institute of Medical Research, Royal North Shore Hospital, University of Sydney, St Leonards, Sydney, New South Wales 2065, Australia

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D E Benn Cancer Genetics, Department of Surgery, Anatomical Pathology, Endocrinology, Endocrine and Oncology Surgery, Kolling Institute of Medical Research, Royal North Shore Hospital, University of Sydney, St Leonards, Sydney, New South Wales 2065, Australia

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A Clarkson Cancer Genetics, Department of Surgery, Anatomical Pathology, Endocrinology, Endocrine and Oncology Surgery, Kolling Institute of Medical Research, Royal North Shore Hospital, University of Sydney, St Leonards, Sydney, New South Wales 2065, Australia

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B G Robinson Cancer Genetics, Department of Surgery, Anatomical Pathology, Endocrinology, Endocrine and Oncology Surgery, Kolling Institute of Medical Research, Royal North Shore Hospital, University of Sydney, St Leonards, Sydney, New South Wales 2065, Australia
Cancer Genetics, Department of Surgery, Anatomical Pathology, Endocrinology, Endocrine and Oncology Surgery, Kolling Institute of Medical Research, Royal North Shore Hospital, University of Sydney, St Leonards, Sydney, New South Wales 2065, Australia

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K L McDonald Cancer Genetics, Department of Surgery, Anatomical Pathology, Endocrinology, Endocrine and Oncology Surgery, Kolling Institute of Medical Research, Royal North Shore Hospital, University of Sydney, St Leonards, Sydney, New South Wales 2065, Australia

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S B Sidhu Cancer Genetics, Department of Surgery, Anatomical Pathology, Endocrinology, Endocrine and Oncology Surgery, Kolling Institute of Medical Research, Royal North Shore Hospital, University of Sydney, St Leonards, Sydney, New South Wales 2065, Australia
Cancer Genetics, Department of Surgery, Anatomical Pathology, Endocrinology, Endocrine and Oncology Surgery, Kolling Institute of Medical Research, Royal North Shore Hospital, University of Sydney, St Leonards, Sydney, New South Wales 2065, Australia

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tested using immunohistochemistry (IHC). Materials and methods Patients and tumors Ethics approval for the study was obtained from the Northern Sydney Area Health Service Human Research Ethics Committee. Informed consent was obtained from patients prior

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