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Marjory Alana Marcello, Lucas Leite Cunha, Fernando Assis Batista and Laura Sterian Ward

Introduction Overweight and/or obesity have been consistently related to the development and progression of different types of cancers during the last decades. An extensive review published a few years ago estimated that approximately 20% of all

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Raquel Santana da Cruz, Johan Clarke, Ana Cristina P Curi, Aseel Al-Yawar, Lu Jin, Ali Baird, M Idalia Cruz, Bhaskar Kallakury and Sonia de Assis

syndrome and obesity among them ( Pandol et al . 2012 ). Epidemiologic studies suggest that obesity, overweight and underlying metabolic dysfunction account for up to 50% of all PDACs ( Bracci 2012 ), and findings from animal studies support this

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Fahmida Rasha, Latha Ramalingam, Lauren Gollahon, Rakshanda Layeequr Rahman, Shaikh Mizanoor Rahman, Kalhara Menikdiwela and Naima Moustaid-Moussa

lifetime risk of developing BC, with approximately 40,920 deaths due to breast cancer in 2018 ( Suganuma et al. 2005 ). Obesity is a complex health condition and contributes to 20% of all cancer-related mortality ( Pierobon & Frankenfeld 2013 , Simpson

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Sunmi Park, Mark C Willingham, Jun Qi and Sheue-Yann Cheng

, Lim et al . 2017 ). These observations raise the possibility that other risk factors could also contribute to the increased incidence of thyroid cancer. One risk factor that has been supported by epidemiological studies is obesity. Extensive

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Ken Chow, Stefano Mangiola, Jaideep Vazirani, Justin S Peters, Anthony J Costello, Christopher M Hovens and Niall M Corcoran

Introduction Having a higher body mass index (BMI) has been associated with a number of solid organ tumors, including prostate cancer ( Khandekar et al . 2011 ). Evidence accumulated over the last two decades consistently links obesity with

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Denise K Reaves, Erika Ginsburg, John J Bang and Jodie M Fleming

their strong link to type 2 diabetes, metabolic syndrome, and cancer, each of which is intimately linked to obesity ( Lee et al . 2010 , Prieto-Hontoria et al . 2011 , Park et al . 2014 a ). Human exposure to POPs occurs through consumption of

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Ana B Crujeiras, Angel Diaz-Lagares, Olafur A Stefansson, Manuel Macias-Gonzalez, Juan Sandoval, Juan Cueva, Rafael Lopez-Lopez, Sebastian Moran, Jon G Jonasson, Laufey Tryggvadottir, Elinborg Olafsdottir, Francisco J Tinahones, Marcos C Carreira, Felipe F Casanueva and Manel Esteller

Introduction The prevalence of obesity and its associated co-disorders is rapidly increasing worldwide. Nowadays, these diseases are considered to be pandemic non-communicable diseases and are a major challenge for the health care system

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Srilatha Swami, Aruna V Krishnan, Jasmaine Williams, Abhishek Aggarwal, Megan A Albertelli, Ronald L Horst, Brian J Feldman and David Feldman

Introduction The incidence of obesity in the general population is rising and becoming widespread worldwide. In the USA, overweight (BMI=25–29.9 kg/m 2 ) and obese (BMI ≥30kg/m 2 ) individuals together constitute almost two-thirds of the

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Catherine M Olsen, Christina M Nagle, David C Whiteman, Roberta Ness, Celeste Leigh Pearce, Malcolm C Pike, Mary Anne Rossing, Kathryn L Terry, Anna H Wu, The Australian Cancer Study (Ovarian Cancer), Australian Ovarian Cancer Study Group, Harvey A Risch, Herbert Yu, Jennifer A Doherty, Jenny Chang-Claude, Rebecca Hein, Stefan Nickels, Shan Wang-Gohrke, Marc T Goodman, Michael E Carney, Rayna K Matsuno, Galina Lurie, Kirsten Moysich, Susanne K Kjaer, Allan Jensen, Estrid Hogdall, Ellen L Goode, Brooke L Fridley, Robert A Vierkant, Melissa C Larson, Joellen Schildkraut, Cathrine Hoyo, Patricia Moorman, Rachel P Weber, Daniel W Cramer, Allison F Vitonis, Elisa V Bandera, Sara H Olson, Lorna Rodriguez-Rodriguez, Melony King, Louise A Brinton, Hannah Yang, Montserrat Garcia-Closas, Jolanta Lissowska, Hoda Anton-Culver, Argyrios Ziogas, Simon A Gayther, Susan J Ramus, Usha Menon, Aleksandra Gentry-Maharaj and Penelope M Webb

Introduction It is widely accepted that being overweight or obese increases a woman's risk of developing endometrial and post-menopausal breast cancer ( Calle & Kaaks 2004 ). The association with ovarian cancer is less clear, largely because

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Adel T Aref, Andrew D Vincent, Michael E O’Callaghan, Sean A Martin, Peter D Sutherland, Andrew J Hoy, Lisa M Butler and Gary A Wittert

obesity. Men who are obese have consistently lower PSA concentrations in serum samples than non-obese men ( Zhang et al. 2015 , 2016 , Bonn et al. 2016 ). The predictive power of the PSA test was not altered by BMI (kg/m 2 ), a relatively crude