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Guoliang Wang Department of Tumor and Immunology, Beijing Children’s Hospital, Capital Medical University, National Center for Children's Health, Beijing, China

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Na Ren Department of Clinical Laboratory Center, Beijing Children’s Hospital, Capital Medical University, Beijing, China

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Shengcai Wang Department of Otorhinolaryngology, Head and Neck Surgery, Beijing Children’s Hospital, Capital Medical University, Beijing, China

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Xuexi Zhang Department of Otorhinolaryngology, Head and Neck Surgery, Beijing Children’s Hospital, Capital Medical University, Beijing, China

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Yanzhen Li Department of Otorhinolaryngology, Head and Neck Surgery, Beijing Children’s Hospital, Capital Medical University, Beijing, China

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Nian Sun Department of Otorhinolaryngology, Head and Neck Surgery, Beijing Children’s Hospital, Capital Medical University, Beijing, China

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Qiaoyin Liu Department of Otorhinolaryngology, Head and Neck Surgery, Beijing Children’s Hospital, Capital Medical University, Beijing, China

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Jie Zhang Department of Otorhinolaryngology, Head and Neck Surgery, Beijing Children’s Hospital, Capital Medical University, Beijing, China

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Wenqi Song Department of Clinical Laboratory Center, Beijing Children’s Hospital, Capital Medical University, Beijing, China

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Xin Ni Department of Otorhinolaryngology, Head and Neck Surgery, Beijing Children’s Hospital, Capital Medical University, Beijing, China

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). All these above studies were conducted in adult patients, and the correlation between serum TSH concentration and risk for pediatric thyroid cancer were not clear. A few studies on serum TSH concentration in pediatric patients ignored some important

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-20-0508
Volume/Issue:
Volume 28: Issue 4
Restricted access
Adam Stenman Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden
Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
Department of Breast, Endocrine Tumors and Sarcoma, Karolinska University Hospital, Stockholm, Sweden

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Samuel Backman Department of Surgical Sciences, Uppsala University, Uppsala, Sweden

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Klara Johansson Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden

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Johan O Paulsson Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden

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Peter Stålberg Department of Surgical Sciences, Uppsala University, Uppsala, Sweden

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Jan Zedenius Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden
Department of Breast, Endocrine Tumors and Sarcoma, Karolinska University Hospital, Stockholm, Sweden

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C Christofer Juhlin Department of Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden
Department of Pathology and Cytology, Karolinska University Hospital, Stockholm, Sweden

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Introduction The incidence of pediatric thyroid cancer is estimated to be 4–5 cases per 100,000 children, making thyroid cancer the most common pediatric endocrine malignancy ( Howlader et al. 2020 ). The bulk of cases are follicular

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-20-0464
Volume/Issue:
Volume 28: Issue 5
Open access
Maria Isabel C Vieira Cordioli Genetic Bases of Thyroid Tumors Laboratory, Division of Endocrinology, Division of Genetics, Department of Morphology and Genetics and Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, Pedro de Toledo 669, 11 andar, 04039‐032, São Paulo, SP, Brazil

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Lais Moraes Genetic Bases of Thyroid Tumors Laboratory, Division of Endocrinology, Division of Genetics, Department of Morphology and Genetics and Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, Pedro de Toledo 669, 11 andar, 04039‐032, São Paulo, SP, Brazil

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Adriano Namo Cury Genetic Bases of Thyroid Tumors Laboratory, Division of Endocrinology, Division of Genetics, Department of Morphology and Genetics and Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, Pedro de Toledo 669, 11 andar, 04039‐032, São Paulo, SP, Brazil

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Janete M Cerutti Genetic Bases of Thyroid Tumors Laboratory, Division of Endocrinology, Division of Genetics, Department of Morphology and Genetics and Division of Endocrinology, Department of Medicine, Escola Paulista de Medicina, Universidade Federal de São Paulo, Pedro de Toledo 669, 11 andar, 04039‐032, São Paulo, SP, Brazil

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that advances in ultrasound imaging technologies have improved diagnosis and, consequently, over time, may have contributed to detect small and asymptomatic pediatric thyroid cancers. Although increased diagnostic scrutiny may account for some of the

Article Type:
Review Article
DOI:
https://doi.org/10.1530/ERC-15-0381
Volume/Issue:
Volume 22: Issue 6
Free access
Barbora Bulanova Pekova Department of Molecular Endocrinology, Institute of Endocrinology, Prague, Czech Republic

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Vlasta Sykorova Department of Molecular Endocrinology, Institute of Endocrinology, Prague, Czech Republic

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Karolina Mastnikova Department of Molecular Endocrinology, Institute of Endocrinology, Prague, Czech Republic

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Eliska Vaclavikova Department of Molecular Endocrinology, Institute of Endocrinology, Prague, Czech Republic

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Jitka Moravcova Department of Molecular Endocrinology, Institute of Endocrinology, Prague, Czech Republic

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Petr Vlcek Department of Nuclear Medicine and Endocrinology, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic

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Lucie Lancova Department of Nuclear Medicine and Endocrinology, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic

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Petr Lastuvka Departments of Otorhinolaryngology and Head and Neck Surgery, 1st Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic

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Rami Katra Department of Ear, Nose and Throat, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic

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Petr Bavor Department of Surgery, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic

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Daniela Kodetova Department of Pathology and Molecular Medicine, 2nd Faculty of Medicine, Charles University and Motol University Hospital, Prague, Czech Republic

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Martin Chovanec Department of Otorhinolaryngology, 3rd Faculty of Medicine, University Hospital Kralovske Vinohrady, Prague, Czech Republic

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Jana Drozenova Department of Pathology, 3rd Faculty of Medicine, University Hospital Kralovske Vinohrady, Prague, Czech Republic

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Radoslav Matej Department of Pathology, 3rd Faculty of Medicine, University Hospital Kralovske Vinohrady, Prague, Czech Republic

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Jaromir Astl Department of Otorhinolaryngology and Maxillofacial Surgery, 3rd Faculty of Medicine and Military University Hospital, Prague, Czech Republic

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Jiri Hlozek Department of Otorhinolaryngology and Maxillofacial Surgery, 3rd Faculty of Medicine and Military University Hospital, Prague, Czech Republic

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Petr Hrabal Department of Pathology, Military University Hospital, Prague, Czech Republic

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Josef Vcelak Department of Molecular Endocrinology, Institute of Endocrinology, Prague, Czech Republic

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Bela Bendlova Department of Molecular Endocrinology, Institute of Endocrinology, Prague, Czech Republic

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the most common genetic alteration in pediatric thyroid cancer ( Nikiforov et al. 1997 , Ricarte-Filho et al. 2013 ). In adult cohorts, RET fusion genes were detected less frequently than in pediatric cohorts ( Santoro et al. 2020 ). Studies

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-23-0117
Volume/Issue:
Volume 30: Issue 12
Open access
Rengyun Liu Laboratory for Cellular and Molecular Thyroid Research, Division of Endocrinology, Diabetes and Metabolism, The Johns Hopkins University School of Medicine, 1830 East Monument Street, Suite 333, Baltimore, Maryland 21287, USA

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Mingzhao Xing Laboratory for Cellular and Molecular Thyroid Research, Division of Endocrinology, Diabetes and Metabolism, The Johns Hopkins University School of Medicine, 1830 East Monument Street, Suite 333, Baltimore, Maryland 21287, USA

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different studies available for the analyzed parameters as presented in the corresponding tables and figures and did not include four studies which were each focused on highly selective special cases, including pediatric thyroid cancer ( Ballester et al

Article Type:
Review Article
DOI:
https://doi.org/10.1530/ERC-15-0533
Volume/Issue:
Volume 23: Issue 3
Free access
Giancarlo Di Giuseppe Pediatric Oncology Group of Ontario, Toronto, Ontario, Canada
Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada

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Aleksandra M Zuk Pediatric Oncology Group of Ontario, Toronto, Ontario, Canada
Health Studies, and the Department of Physical and Environmental Sciences, University of Toronto Scarborough, Toronto, Ontario, Canada

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Jonathan D Wasserman Division of Endocrinology, The Hospital for Sick Children, Toronto, Ontario, Canada
Department of Pediatrics, University of Toronto, Toronto, Ontario, Canada

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Jason D Pole Pediatric Oncology Group of Ontario, Toronto, Ontario, Canada
Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada
Centre for Health Services Research, The University of Queensland, Brisbane, Queensland, Australia

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Alghamdi B Al-Hindi H 2019 Lung metastasis in pediatric thyroid cancer: radiological pattern, molecular genetics, response to therapy, and outcome . Journal of Clinical Endocrinology and Metabolism 104 103 – 110 . ( https://doi.org/10.1210/jc

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-19-0463
Volume/Issue:
Volume 27: Issue 6
Restricted access
Sarah E Mayson Division of Endocrinology, Metabolism and Diabetes, University of Colorado School of Medicine, Aurora, Colorado, USA

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Christine M Chan Section of Endocrinology, Department of Pediatrics, Children’s Hospital Colorado, University of Colorado School of Medicine, Aurora, Colorado, USA

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Bryan R Haugen Division of Endocrinology, Metabolism and Diabetes, University of Colorado School of Medicine, Aurora, Colorado, USA
University of Colorado Cancer Center, Aurora, Colorado, USA

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MA Ishak M Afifi MA Shafie AE Ali MA Zekri W Alfaar AS Rashed WM 2018 Risk of second malignancies among survivors of pediatric thyroid cancer . International Journal of Clinical Oncology 23 625 – 633 . ( https://doi.org/10

Article Type:
Review Article
DOI:
https://doi.org/10.1530/ERC-21-0161
Volume/Issue:
Volume 28: Issue 10
Free access
Sasha R Howard Centre for Endocrinology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, UK
Department of Paediatric Endocrinology, Barts Health NHS Trust, London, UK

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Sarah Freeston Whipps Cross Hospital, Barts Health NHS Trust, London, UK

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Barney Harrison Retired Endocrine Surgeon, Sheffield, UK

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Louise Izatt Department of Clinical and Cancer Genetics, Guy’s and St Thomas’ NHS Foundation Trust, London, UK

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Sonali Natu Department of Pathology, University Hospital of North Tees and Hartlepool NHS Foundation Trust, Stockton-on-Tees, UK

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Kate Newbold Department of Clinical Oncology, Royal Marsden Hospital Foundation Trust, London, UK

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Sabine Pomplun Department of Pathology, University College London Hospital NHS Foundation Trust, London, UK

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Helen A Spoudeas Department of Paediatric Endocrinology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK

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Sophie Wilne Department of Paediatric Oncology, Nottingham University Hospital’s NHS Trust, Nottingham, UK

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Tom R Kurzawinski Department of Endocrine Surgery, University College London Hospitals NHS Foundation Trust, London, UK
Department of Paediatric Endocrine Surgery, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK

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Mark N Gaze Department of Clinical Oncology, University College London Hospitals NHS Foundation Trust, London, UK
Department of Clinical Oncology, Great Ormond Street Hospital for Children NHS Foundation Trust, London, UK

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perspective of the risk, presentation, and outcomes of pediatric thyroid cancer, presentation . JAMA Otolaryngology– Head and Neck Surgery 142 472– 478 . ( https://doi.org/10.1001/jamaoto.2016.0104 ) Altincik A Demir K Abaci A Bober E Buyukgebiz

Article Type:
Other
DOI:
https://doi.org/10.1530/ERC-22-0035
Volume/Issue:
Volume 29: Issue 11
Open access
Cristina Romei Departments of, Endocrinology and Metabolism, Oncology, Surgery, Department of Internal Medicine, AMBISEN Center, University of Pisa, 56100 Pisa, Italy

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Raffaele Ciampi Departments of, Endocrinology and Metabolism, Oncology, Surgery, Department of Internal Medicine, AMBISEN Center, University of Pisa, 56100 Pisa, Italy

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Pinuccia Faviana Departments of, Endocrinology and Metabolism, Oncology, Surgery, Department of Internal Medicine, AMBISEN Center, University of Pisa, 56100 Pisa, Italy

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Laura Agate Departments of, Endocrinology and Metabolism, Oncology, Surgery, Department of Internal Medicine, AMBISEN Center, University of Pisa, 56100 Pisa, Italy

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Eleonora Molinaro Departments of, Endocrinology and Metabolism, Oncology, Surgery, Department of Internal Medicine, AMBISEN Center, University of Pisa, 56100 Pisa, Italy

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Valeria Bottici Departments of, Endocrinology and Metabolism, Oncology, Surgery, Department of Internal Medicine, AMBISEN Center, University of Pisa, 56100 Pisa, Italy

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Fulvio Basolo Departments of, Endocrinology and Metabolism, Oncology, Surgery, Department of Internal Medicine, AMBISEN Center, University of Pisa, 56100 Pisa, Italy

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Paolo Miccoli Departments of, Endocrinology and Metabolism, Oncology, Surgery, Department of Internal Medicine, AMBISEN Center, University of Pisa, 56100 Pisa, Italy

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Furio Pacini Departments of, Endocrinology and Metabolism, Oncology, Surgery, Department of Internal Medicine, AMBISEN Center, University of Pisa, 56100 Pisa, Italy

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Aldo Pinchera Departments of, Endocrinology and Metabolism, Oncology, Surgery, Department of Internal Medicine, AMBISEN Center, University of Pisa, 56100 Pisa, Italy
Departments of, Endocrinology and Metabolism, Oncology, Surgery, Department of Internal Medicine, AMBISEN Center, University of Pisa, 56100 Pisa, Italy

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Rossella Elisei Departments of, Endocrinology and Metabolism, Oncology, Surgery, Department of Internal Medicine, AMBISEN Center, University of Pisa, 56100 Pisa, Italy

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, according to the literature, they are more frequent in pediatric thyroid cancer and in cancer patients with a previous history of radiation exposure ( Nikiforov et al . 1997 , Elisei et al . 2001 ). Although it is a fact that RET/PTC3 is usually

Article Type:
Research Article
DOI:
https://doi.org/10.1677/ERC-07-0130
Volume/Issue:
Volume 15: Issue 2
Free access
B Jarząb
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D Handkiewicz-Junak
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J Włoch
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), though not completely without fluctuation ( Niedziela et al. 2004 , Leenhardt et al. 2004 ). However, over the past ~60 years, pediatric thyroid cancer incidence has had two distinct peaks. The first, in the mid-20th century, was due to use

Article Type:
Review Article
DOI:
https://doi.org/10.1677/erc.1.00880
Volume/Issue:
Volume 12: Issue 4
Free access