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Department of Endocrinology, St Bartholomew’s Hospital, Barts Health NHS Trust, London, UK
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Department of Endocrinology, St Bartholomew’s Hospital, Barts Health NHS Trust, London, UK
Department of Diabetes and Endocrinology, University College London Hospital, London, UK
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Introduction Pheochromocytomas (PCCs) are neuroendocrine tumors that originate from chromaffin cells of the adrenal medulla or autonomic nervous system, where they are termed paragangliomas (PGLs). The majority of the morbidity associated with
Department of Molecular Oncology, King Faisal Specialist Hospital & Research Centre, Riyadh, Saudi Arabia
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Département de Médecine Génomique des Tumeurs et des Cancers, Fédération de Génétique et de Médecine Génomique, Assistance Publique-Hôpitaux de Paris (AP-HP) Centre, Hôpital Européen Georges Pompidou, Paris, France
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Introduction Pheochromocytomas (PCCs) and paragangliomas (PGLs, abbreviated together as PPGLs) are rare neuroendocrine tumors of the adrenal medulla and the peripheral autonomic ganglia, respectively ( Lenders 2014 ). They arise from
Department of Health Science, Universidad de Alcalá, Madrid, Spain
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Group of Endocrine Disorders, Institut d’Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain
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Group of Endocrine Disorders, Institut d’Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), Barcelona, Spain
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Introduction Pheochromocytomas are rare neuroendocrine tumours that produce catecholamines ( Lenders et al. 2014 ). Anaesthetic induction and surgical manipulation of the tumour can precipitate the release of an excessive amount of
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Introduction Pheochromocytomas and paragangliomas are tumors of the overall paraganglial system, mainly the adrenal glands, the retroperitoneum, the pelvis, the thorax, and the skullbase and neck regions ( Neumann 2008 ). Such paraganglial tumors
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Introduction Pheochromocytomas and paragangliomas (PPGLs) are rare chromaffin-cell tumors from the adrenal medulla and the sympathetic paravertebral ganglia of the thorax, abdomen, and pelvis, as well as along the parasympathetic ganglia at
INSERM UMR1048, I2MC, Toulouse, France
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Laboratory of Biochemistry and Molecular Biology, IFB-CHU, Toulouse, France
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Department of Cardiology Toulouse University, Hôpital Rangueil, Toulouse, France
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Univ. Lille, Inserm, CHU Lille, U1286 – Infinite – Institute for Translational Research in Inflammation, Lille, France
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Laboratory of Biochemistry and Molecular Biology, IFB-CHU, Toulouse, France
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Introduction Pheochromocytoma–paraganglioma (PPGL) are rare tumors ( Berends et al. 2018 ) that produce and store catecholamines. The release of excessive amounts of catecholamines can lead to life-threatening cardiovascular complications
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Introduction Pheochromocytomas and paragangliomas (PPGLs) are rare, catecholamine-secreting tumors arising from the chromaffin cells of the adrenal medulla and extra-adrenal neural crest tissues, which run from the skull base to the pelvis
The University of Sydney, Sydney, New South Wales, Australia
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Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Copenhagen N, Denmark
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The University of Sydney, Sydney, New South Wales, Australia
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Bioinformatics Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
Department of Medical Biology, University of Melbourne, Melbourne, Victoria, Australia
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The Department of Pathology, University of Melbourne, Parkville, Victoria, Australia
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The University of Sydney, Sydney, New South Wales, Australia
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Bioinformatics Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia
Department of Medical Biology, University of Melbourne, Melbourne, Victoria, Australia
The Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia
The Department of Mathematics and Statistics, University of Melbourne, Parkville, Victoria, Australia
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Cancer Diagnosis and Pathology Group, Kolling Institute, Royal North Shore Hospital, Sydney, New South Wales, Australia
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The Department of Pathology, University of Melbourne, Parkville, Victoria, Australia
School of Cancer Medicine, La Trobe University, Bundoora, Victoria, Australia
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The Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia
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The University of Sydney, Sydney, New South Wales, Australia
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The Department of Pathology, University of Melbourne, Parkville, Victoria, Australia
The Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, Victoria, Australia
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Introduction Pheochromocytomas (PC) and paragangliomas (PGLs) are neuroendocrine tumors derived from neural crest cells of the sympathetic and parasympathetic nervous system – PCs arising in the adrenal medulla and PGLs in paraganglia outside
Expert Center for Rare Endocrine Diseases, Sofia, Bulgaria
European Network on Rare Endocrine Conditions (ENDO-ERN)
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Expert Center for Rare Endocrine Diseases, Sofia, Bulgaria
European Network on Rare Endocrine Conditions (ENDO-ERN)
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Expert Center for Rare Endocrine Diseases, Sofia, Bulgaria
European Network on Rare Endocrine Conditions (ENDO-ERN)
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Introduction Cardiovascular disturbances are the major clinical manifestations of pheochromocytoma. Arterial hypertension is the leading symptom in approximately 90% of all patients, usually with a paroxysmal course, severe, malignant or
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Introduction Pheochromocytomas and paragangliomas (PPGLs) are rare neuroendocrine tumors derived from chromaffin cells of the adrenal medulla and paraganglia, respectively ( Jimenez 2018 ). Each year, approximately 500–1600 new cases of PPGLs