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thyroid cancer ( Hizawa et al . 1996 ). No detail of the cytological feature was given in the report. In 2010, Koo and coworkers from South Korea described the cytological features of five CMV-PTCs as well as reviewing 10 cases from the previous studies
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squamous cell carcinoma of thyroid. This review aims to address this gap of knowledge by analysing the features of squamous cell carcinoma of thyroid and their relationships with other tumours of the thyroid gland. Method Primary squamous cell
Ipatimup – Instituto de Patologia e Imunologia Molecular da Universidade do Porto, Porto, Portugal
ICBAS – Instituto de Ciências Biomédicas Abel Salazar da Universidade do Porto, Porto, Portugal
FMUP – Faculdade de Medicina da Universidade do Porto, Porto, Portugal
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Ipatimup – Instituto de Patologia e Imunologia Molecular da Universidade do Porto, Porto, Portugal
FMUP – Faculdade de Medicina da Universidade do Porto, Porto, Portugal
Department of Pathology, Centro Hospitalar e Universitário de São João, Porto, Portugal
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Ipatimup – Instituto de Patologia e Imunologia Molecular da Universidade do Porto, Porto, Portugal
FMUP – Faculdade de Medicina da Universidade do Porto, Porto, Portugal
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Ipatimup – Instituto de Patologia e Imunologia Molecular da Universidade do Porto, Porto, Portugal
FMUP – Faculdade de Medicina da Universidade do Porto, Porto, Portugal
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animal models, and this review will only focus on them. In PanNENs, the most validated mouse models have been genetically programmed: (1) to conditionally activate oncogenes under relevant promoters (e.g. insulin and preproglucagon) or (2) to mimic PanNET
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review is to give detailed insights on the genetics, natural history and management of MEN2B, in addition to specific points that should be detailed in future large-scale studies. Genetics of MEN2B MEN2B, similar to MEN2A, is due to autosomal
Department of Nuclear Medicine and Thyroid Centre, Section of Endocrinology and Diabetology, Nuclear Medicine, Endocrine Unit, Oncology Institute of Southern Switzerland, Bellinzona, 6500, Switzerland
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entire process chain and are easier to manage in clinical practice. These characteristics give ProCT great potential to replace CT as a marker for detecting and managing MTC patients. To date, no review on this topic has, to our knowledge, been published
Endocrinology Department, ‘C.I. Parhon’ National Institute of Endocrinology, Bucharest, Romania
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Pathology Department, Reference Center for Rare Pituitary Diseases HYPO, ‘Groupement Hospitalier Est’ Hospices Civils de Lyon, Bron, France
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Neurosurgery Department, Reference Center for Rare Pituitary Diseases HYPO, ‘Groupement Hospitalier Est’ Hospices Civils de Lyon, Bron, France
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Endocrinology Department, Reference Center for Rare Pituitary Diseases HYPO, ‘Groupement Hospitalier Est’ Hospices Civils de Lyon, Bron, France
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tumors, followed by a systematic review of all published cases, analyzing both treatment response and potential predictors of response and finishing with research and clinical perspectives. The aim is to highlight key clinical aspects that can already be
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Department of Nuclear Medicine, Postgraduate Department, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University, 600 Yishan Road, Shanghai 200233, China
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Department of Nuclear Medicine, Postgraduate Department, Shanghai Sixth People's Hospital, Shanghai Jiao Tong University, 600 Yishan Road, Shanghai 200233, China
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131 I-SPECT/CT imaging fusion techniques, rare metastasis in DTC is increasingly becoming an incidental finding ( Chen et al . 2008 , Qiu et al . 2011 ). This pictorial review highlights the diagnostic aspects of 131 I-SPECT/CT for the localization
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interpretation, while helping to appropriately select patients that will benefit from molecular testing. This review is aimed to contribute to a better knowledge of the available molecular tests, their technical characteristics and clinical performance, through a
Center for Neuroendocrine and Endocrine Tumors, University Hospital Basel, Basel Switzerland
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Clinic of Radiology and Nuclear Medicine, University Hospital, Basel, Switzerland
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is not a suitable diagnostic tool. Declaration of interest The authors declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of this review. Funding The study was supported by the Swiss
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suppression with luteinizing hormone releasing factor (LHRH) agonists offer different mechanisms to suppress estrogen production and action and these agents have better safety profiles compared with tamoxifen. This article will review each of these hormonal