Introduction Thyroid cancer is the most common form of endocrine malignancies. Follicular thyroid carcinoma (FTC) has an incidence of 15–20% and is the second most frequent thyroid carcinoma ( Ban et al . 2012 ). If FTC disseminates, it
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Denise Zwanziger, Julia Badziong, Saskia Ting, Lars Christian Moeller, Kurt Werner Schmid, Udo Siebolts, Claudia Wickenhauser, Henning Dralle, and Dagmar Fuehrer
Eric Y Lian, Sarah M Maritan, Jessica G Cockburn, Katayoon Kasaian, Mathieu J F Crupi, David Hurlbut, Steven J M Jones, Sam M Wiseman, and Lois M Mulligan
, Romei et al . 2016 ). Constitutive activation of RET by specific point mutations gives rise to medullary thyroid carcinoma (MTC), a tumour of thyroid C-cells, as part of the familial cancer syndrome multiple endocrine neoplasia 2 (MEN2), and also occur
Bruno Heidi Nozima, Thais Biude Mendes, Gustavo José da Silva Pereira, Rodrigo Pinheiro Araldi, Edna Sadayo Miazato Iwamura, Soraya Soubhi Smaili, Gianna Maria Griz Carvalheira, and Janete Maria Cerutti
thyroid carcinoma cell lines. Materials and methods Cell culture The Nthy-ori 3–1 (human thyroid follicular epithelial derived from normal thyroid tissue), WRO and FTC-236 (human follicular thyroid carcinoma cell lines), TPC1 (human papillary
Giuseppe Palladino, Tiziana Notarangelo, Giuseppe Pannone, Annamaria Piscazzi, Olga Lamacchia, Lorenza Sisinni, Girolamo Spagnoletti, Paolo Toti, Angela Santoro, Giovanni Storto, Pantaleo Bufo, Mauro Cignarelli, Franca Esposito, and Matteo Landriscina
Introduction The vast majority of thyroid carcinomas (TCs) are well-differentiated tumors, usually curable by the combination of surgery, radioiodine ablation and long-term thyroid-stimulating hormone (TSH) suppressive therapy ( Mazzaferri
De-tao Yin, Wenxun Wu, Mingchuang Li, Qi-en Wang, Hongqiang Li, Yongfei Wang, Yifeng Tang, and Mingzhao Xing
Introduction Thyroid carcinoma is the most common endocrine malignancy, and papillary thyroid carcinoma (PTC) accounts for over 90% of all thyroid malignancies ( Yin et al . 2010 a ). The incidence of thyroid cancer, mainly PTC, has been rising
Debora Degl'Innocenti, Paola Romeo, Eva Tarantino, Marialuisa Sensi, Giuliana Cassinelli, Veronica Catalano, Cinzia Lanzi, Federica Perrone, Silvana Pilotti, Ettore Seregni, Marco A Pierotti, Angela Greco, and Maria Grazia Borrello
undifferentiated anaplastic (ATC) carcinomas, originates from thyrocytes. Papillary thyroid carcinoma (PTC), a WDTC histotype, is the most prevalent thyroid malignancy. It is usually associated with a good prognosis and therapeutic response; nevertheless, ∼10% of
Yeon-Sook Choi, Hyemi Kwon, Mi-Hyeon You, Tae Yong Kim, Won Bae Kim, Young Kee Shong, Min Ji Jeon, and Won Gu Kim
Introduction Anaplastic thyroid carcinoma (ATC) is a rare type of thyroid cancer with highly aggressive clinical features ( Kebebew et al. 2005 , Kurata et al. 2016 , Subbiah et al. 2018 , Lee & Park 2021 ). The median overall survival
Astrid Kehlen, Monique Haegele, Katja Menge, Kathrin Gans, Uta-Dorothee Immel, Cuong Hoang-Vu, Thomas Klonisch, and Hans-Ulrich Demuth
al . 2011 ). In papillary thyroid carcinoma (PTC), CCL2 is correlated with lymph node metastasis and tumor recurrence ( Tanaka et al . 2009 ). Interestingly, the oncogenic fusion protein RET/PTC expressed in PTC activates the transcription factor NF
Vera Tiedje, Martin Stuschke, Frank Weber, Henning Dralle, Laura Moss, and Dagmar Führer
Introduction Anaplastic thyroid carcinoma (ATC) is an orphan disease responsible for most thyroid carcinoma-associated deaths. Incidence is estimated to be 1–2 per million per year ( Smallridge et al . 2012 ). The histological diagnosis of
Bogusz Trojanowicz, Lars Brodauf, Carsten Sekulla, Kerstin Lorenz, Rainer Finke, Henning Dralle, and Cuong Hoang-Vu
gene expression in the processes of carcinogenesis or proliferation. In this study, we investigated the influence of AUF1 on ARE-regulated cell cycle modulators, previously described to be crucial for thyroid carcinoma progression. We also determined