important target for cancer therapy. Fibroblasts within the tumour stroma are critically involved in promoting tumour growth and angiogenesis through secretion of soluble factors, synthesis of extracellular matrix and direct cell–cell interaction. Tumour-associated
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C Verdelli, L Avagliano, P Creo, V Guarnieri, A Scillitani, L Vicentini, G B Steffano, E Beretta, L Soldati, E Costa, A Spada, G P Bulfamante, and S Corbetta
Xiang Zhang, Ya Hu, Ming Cui, Mengyi Wang, Xiaobin Li, Yalu Zhang, Sen Yang, Surong Hua, Meiping Shen, and Quan Liao
profile the transcriptome of 27,251 cells isolated from 4 PA tissues. Our work revealed the cellular heterogeneity, transcriptional states, and immune cell diversity inside PA tissues, underlying the role of tumour-associated fibroblasts (TAFs) and immune
Pedro Marques, Sayka Barry, Eivind Carlsen, David Collier, Amy Ronaldson, Sherine Awad, Neil Dorward, Joan Grieve, Nigel Mendoza, Samiul Muquit, Ashley B Grossman, Frances Balkwill, and Márta Korbonits
fibroblasts undergo activation in tumours, often then termed as tumour-associated fibroblasts (TAFs) ( Cirri & Chiarugi 2012 , Shiga et al. 2015 ). TAFs are an important source of cytokines and growth factors which contribute to their pro-tumoural effects
Chiara Verdelli, Irene Forno, Annamaria Morotti, Riccardo Maggiore, Gilberto Mari, Leonardo Vicentini, Stefano Ferrero, Elisabetta Kuhn, Valentina Vaira, and Sabrina Corbetta
. Oncogene 31 27 – 38 . ( https://doi.org/10.1038/onc.2011.209 ) Verdelli C Avagliano L Creo P Guarnieri V Scillitani A Vicentini L Steffano GB Beretta E Soldati L Costa E et al . 2015a Tumour-associated fibroblasts contribute to
Filomena Cetani, Claudio Marcocci, Liborio Torregrossa, and Elena Pardi
Soldati L Costa E , et al . 2015 Tumour-associated fibroblasts contribute to neoangiogenesis in human parathyroid neoplasia . Endocrine-Related Cancer 22 . ( https://doi.org/10.1530/ERC-14-0161 ) 25515730 Verdelli C Forno I Morotti A
W Nathaniel Brennen, Samuel R Denmeade, and John T Isaacs
.1002/pmic.200700089 ). Paunescu V Bojin FM Tatu CA Gavriliuc OI Rosca A Gruia AT Tanasie G Bunu C Crisnic D Gherghiceanu M 2011 Tumour-associated fibroblasts and mesenchymal stem cells: more similarities than differences
Vincenzo Condello, Filomena Cetani, Maria Denaro, Liborio Torregrossa, Elena Pardi, Paolo Piaggi, Simona Borsari, Anello Marcello Poma, Lucia Anna Muscarella, Paolo Graziano, Maria Grazia Chiofalo, Andrea Repaci, Giovanni Tallini, Francesco Boi, Gabriele Materazzi, Fulvio Basolo, and Claudio Marcocci
L Costa E et al . 2015 Tumour-associated fibroblasts contribute to neoangiogenesis in human parathyroid neoplasia . Endocrine-Related Cancer 22 87 – 98 . ( https://doi.org/10.1530/ERC-14-0161 ) Verdelli C Avagliano L Guarnieri V
