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latest trends in MTC and demonstrated the detailed subgroup trends for the first time, based on the Surveillance, Epidemiology, and End Results (SEER) program. The results of our study indicate that the incidence and mortality of MTC in the USA is still
University of Alabama at Birmingham, Department of Surgery, Division of Surgical Oncology, Birmingham, Alabama, USA
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Susan Leslie Clinic for Neuroendocrine Tumors, Odette Cancer Centre - Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Clinical evaluative sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada
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Susan Leslie Clinic for Neuroendocrine Tumors, Odette Cancer Centre - Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
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Susan Leslie Clinic for Neuroendocrine Tumors, Odette Cancer Centre - Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Clinical evaluative sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada
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Susan Leslie Clinic for Neuroendocrine Tumors, Odette Cancer Centre - Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Clinical evaluative sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada
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Susan Leslie Clinic for Neuroendocrine Tumors, Odette Cancer Centre - Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Clinical evaluative sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada
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Susan Leslie Clinic for Neuroendocrine Tumors, Odette Cancer Centre - Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Clinical evaluative sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada
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associated with inferior OS and CSS compared to no SPC. Methods Study design and data sources We performed a retrospective population-based cohort study using the Surveillance, Epidemiology, and End Results (SEER) program. SEER collects patient
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, Epidemiology, and End Results (SEER) database from 1992 to 2009 who had DTC as their only malignancy. Histopathology inclusion criteria were papillary or follicular carcinomas (ICD-O-3 C73.9; histology 8050, 8260, 8330, 8331, 8332, 8335, 8340, 8341, 8342, or
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data from the Surveillance, Epidemiology, and End Result (SEER) program and literature to clarify these gaps of knowledge. Materials and methods Patient selection from the SEER database MTT cases were searched from 1975 to 2016 among 18 SEER
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2000 and 2009, which was the highest among all cancers ( Siegel et al. 2013 ). The Surveillance, Epidemiology and End Results (SEER) program has reported the age-adjusted incidence rate of thyroid cancer to be 13.5 per 100,000 people in the general
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Department of Internal Medicine, Division of Gastroenterology, Mount Sinai School of Medicine, 5 East 98th Street, 11th Floor, New York, New York 10029, USA
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Department of Internal Medicine, Division of Gastroenterology, Mount Sinai School of Medicine, 5 East 98th Street, 11th Floor, New York, New York 10029, USA
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Department of Internal Medicine, Division of Gastroenterology, Mount Sinai School of Medicine, 5 East 98th Street, 11th Floor, New York, New York 10029, USA
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develop metastatic disease. It is difficult to predict survival patterns in patients with SICs due to their heterogeneous biological behavior ( Modlin et al . 2008 ). The Surveillance, Epidemiology, and End Results (SEER) database predicts 5-year survival
Cancer Prognostics and Health Outcomes Unit, Division of Urology, University of Montréal Health Center, Montréal, Québec, Canada
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Department of Surgical and Diagnostic Integrated Sciences (DISC), University of Genova, Genova, Italy
Department of Urology, IRCCS Policlinico San Martino, Genova, Italy
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Martini-Klinik Prostate Cancer Center, University Hospital Hamburg-Eppendorf, Hamburg, Germany
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Department of Urology, University Hospital Frankfurt, Frankfurt am Main, Germany
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Department of Urology, IEO European Institute of Oncology, IRCCS, Milan, Italy
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Department of Urology and Division of Experimental Oncology, URI, Urological Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy
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Department of Urology, University Hospital Hamburg-Eppendorf, Hamburg, Germany
Department of Urology, Koc University Hospital, Istanbul, Turkey
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Department of Urology, IRCCS Policlinico San Martino, Genova, Italy
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Departments of Urology, Weill Cornell Medical College, New York, New York, USA
Department of Urology, University of Texas Southwestern, Dallas, Texas, USA
Hourani Center for Applied Scientific Research, Al-Ahliyya Amman University, Amman, Jordan
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/ethnicity, in overall as well as in stage-specific analyses. We tested these relationships within Surveillance, Epidemiology, and End Results (SEER) database (2004–2018). Materials and methods Study population The SEER database samples 48% of the USA
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. 2009 , Li et al . 2013 ). The annual percent change that was 2.4% from 1980 to 1997 in the USA increased to 6.6% from 1997 to 2009 according to Cancer of The Thyroid – SEER Stat Fact Sheets ( Howlader et al . 2014 ). Although there are solid
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Endocrinology, Mount Sinai Medical Center, Department of Clinical Medicine and Surgery, Endocrinology, Erasmus MC, Department of Internal Medicine, Soroka University Medical Center and the Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheeba, Israel
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and End Results (SEER) database is publicly available, different groups had used the same data and reported similar IRs over similar time periods. In the majority of cases, we included all papers as the studies reported the incidence of NETs using
Department of Urology IEO European Institute of Oncology, IRCCS, Via Ripamonti, Milan, Italy
Università degli Studi di Milano, Milan, Italy
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Department of Neurosciences, Science of Reproduction and Odontostomatology, University of Naples Federico II, Naples, Italy
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Department of Urology, Medical University of Graz, Graz, Austria
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Università degli Studi di Milano, Milan, Italy
Department of Urology, IRCCS Policlinico San Donato, Milan, Italy
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Department of Urology, University Hospital Frankfurt, Goethe University Frankfurt am Main, Frankfurt am Main, Germany
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Division of Experimental Oncology/Unit of Urology, URI, Urological Research Institute, IRCCS San Raffaele Scientific Institute, Milan, Italy
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Department of Oncology and Haemato-Oncology, Università degli Studi di Milano, Milan, Italy
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Department of Oncology and Haemato-Oncology, Università degli Studi di Milano, Milan, Italy
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Department of Oncology and Haemato-Oncology, Università degli Studi di Milano, Milan, Italy
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Department of Urology, IRCCS Ospedale Galeazzi - Sant'Ambrogio, Milan, Italy
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Department of Oncology and Haemato-Oncology, Università degli Studi di Milano, Milan, Italy
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Department of Oncology and Haemato-Oncology, Università degli Studi di Milano, Milan, Italy
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relied on the Surveillance Epidemiology and End Results (SEER) database to address this objective. Materials and methods Data source and study population Within the SEER database (2004–2020), we identified newly diagnosed and histologically