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Jaydira Del Rivero Developmental Therapeutics Branch, National Cancer Institute, National Institutes of Health, Bethesda, USA

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Josh Mailman NorCal CarciNET Community, Oakland, California, USA

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Michael W Rabow Department of Internal Medicine, Division of Palliative Medicine, University of California, San Francisco, San Francisco, California, USA

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Jennifer A Chan Harvard Medical School, Program in Carcinoid and Neuroendocrine Tumors, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA

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Sarah Creed Good Shepherd Community Care, Harvard Kennedy School, Natick, Massachusetts, USA

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Hagen F Kennecke Providence Cancer Institute Franz Clinic, Portland Providence Medical Center, Portland, Oregon, USA

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Janice Pasieka Department of Surgery, Section of General Surgery, University of Calgary, Cumming School of Medicine, Calgary, Canada

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Jennifer Zuar Department of Internal Medicine, Division of Geriatrics and Palliative Medicine, Alpert Medical School, Providence, Rhode Island, USA

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Simron Singh Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada

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Lauren Fishbein Department of Medicine, Division of Endocrinology, Metabolism and Diabetes, Department of Biomedical Informatics, University of Colorado School of Medicine, Aurora, Colorado, USA

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larger approach to care and should be offered to those at any point in their cancer journey. Hospice differs from palliative care since it provides care specifically at the end of life and in a place which a patient calls home, be it a private residence

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T P Links
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K M van Tol
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P L Jager
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J Th M Plukker
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D A Piers
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H M Boezen
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R P F Dullaart
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E G E de Vries
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W J Sluiter
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mild and that treatment of this tumour type, which consists of thyroidectomy followed by high-dose radioiodine and life-long thyroid hormone therapy, is highly successful. Nonetheless, it is still not known whether this treatment adversely affects the

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Benjamin Easton White Department of Gastroenterology, Hampshire Hospitals NHS Foundation Trust, Basingstoke, Hampshire, UK

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Maralyn R Druce Centre for Endocrinology, Barts and the London School of Medicine and Dentistry, London, UK

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Simona Grozinsky-Glasberg Neuroendocrine Tumor Unit, ENETS Center of Excellence, Department of Endocrinology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel

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Rajaventhan Srirajaskanthan King’s Health Partners ENETS Centre of Excellence, Kings College hospital, London, UK

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Eva Maria Gamper Eva Maria Gamper – Innsbruck Institute of Patient-centered Outcome Research (IIPCOR), Innsbruck, Austria

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Debra Gray Department of Psychology, University of Winchester, Hampshire, UK

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Ruben Mujica-Mota Academic Unit of Health Economics, Institute of Health Sciences, University of Leeds, Leeds, UK

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John K Ramage Department of Gastroenterology, Hampshire Hospitals NHS Foundation Trust, Basingstoke, Hampshire, UK
King’s Health Partners ENETS Centre of Excellence, Kings College hospital, London, UK

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showed that fatigue, loss of well-being, lack of appetite, and drowsiness were the most prominent symptoms towards the end of life ( Hallet et al. 2019 ). Fatigue is a prominent symptom in all QoL studies in NET, is greater than the background

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Charlotte L Bevan Department of Surgery & Cancer, Imperial College London, London, UK

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had screened ‘Life Story’, their excellent Horizon special on the discovery of the structure of DNA. Perhaps it was my enthusiasm for, and loquaciousness on, this subject that clinched me the offer from King’s. So you might be forgiven for thinking the

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Constantine A Stratakis Section on Endocrinology and Genetics (SEGEN), Inter‐Institute Pediatric Endocrinology Training Program, NIH, Bethesda, Maryland 20892, USA
Section on Endocrinology and Genetics (SEGEN), Inter‐Institute Pediatric Endocrinology Training Program, NIH, Bethesda, Maryland 20892, USA
Section on Endocrinology and Genetics (SEGEN), Inter‐Institute Pediatric Endocrinology Training Program, NIH, Bethesda, Maryland 20892, USA

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below). My grandmother did not share this fascination with me: at the end of the summer season all my ‘rocks’ were thrown away, and I would start again the following summer . My first microscope, received at the age of 10 or so, was used to look at bugs

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Zoran Culig Experimental Urology, Department of Urology, Innsbruck Medical University, Anichstrasse 35, A-6020 Innsbruck, Austria

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Europe and the US have been affected and there is not a light at the end of the tunnel. Public organizations and agencies are faced with the problem of how to distribute a reduced amount of money to a growing number of competent researchers. Several

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Theodora S Ross Department of Internal Medicine and High-Risk Cancer Program, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, Texas 75390-8852, USA

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. Her death came suddenly. In August 1993, she was everybody's dancing partner at her brother's wedding. A month later, she fell forever silent, surrounded by family in Maine Hospital and an era ended. Or so it seemed. As with the onset of cancer and its

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Fabiana Cillo
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Magda de Eguileor
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Fulvio Gandolfi
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Tiziana A L Brevini
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, Sridhar et al. 2004 ). In the previous studies, we demonstrated that A-1254 interacts with gene expression, affecting mRNA stability by altering the length of the 3′-end poly(A) tail of a number of specific genes in different experimental models

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Rachana Rao Battaje Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Mumbai, India

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Dulal Panda Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Mumbai, India

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the mitotic spindle apparatus, which is responsible for the segregation of chromosomes ( Kline-Smith & Walczak 2004 , Kwon & Scholey 2004 ). During the metaphase, the plus ends of microtubules undergo elongation and shortening for probing and binding

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Julie Abildgaard Department of Growth and Reproduction, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
The Centre for Physical Activity Research, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark

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Hein Vincent Stroomberg Copenhagen Prostate Cancer Center, Department of Urology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark

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A Kirstine Bang Department of Growth and Reproduction, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark

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Jakob Albrethsen Department of Growth and Reproduction, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark

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Laura Smedegaard Kruuse Department of Growth and Reproduction, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark

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Anders Juul Department of Growth and Reproduction, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark

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Klaus Brasso Copenhagen Prostate Cancer Center, Department of Urology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark

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Andreas Røder Copenhagen Prostate Cancer Center, Department of Urology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark

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Niels Jørgensen Department of Growth and Reproduction, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
International Center for Research and Research Training in Endocrine Disruption of Male Reproduction and Child Health (EDMaRC), Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark

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total testosterone in conditions that might alter sex hormone-binding globulin (SHBG) or when total testosterone is in the lower end of normal range ( Corona et al. 2020 ). Thus, the focus of previous studies on serum total testosterone alone is not

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