Search Results

You are looking at 1 - 10 of 1,382 items for :

  • Refine by access: All content x
Clear All
Chi-Yu Kuo Department of Surgery, MacKay Memorial Hospital and Mackay Medical College, Taipei, Taiwan

Search for other papers by Chi-Yu Kuo in
Google Scholar
PubMed
Close
,
Yuan-Ching Chang Department of Surgery, MacKay Memorial Hospital and Mackay Medical College, Taipei, Taiwan

Search for other papers by Yuan-Ching Chang in
Google Scholar
PubMed
Close
,
Ming-Nan Chien Division of Endocrinology and Metabolism, Department of Internal Medicine, MacKay Memorial Hospital and Mackay Medical College, Taipei, Taiwan

Search for other papers by Ming-Nan Chien in
Google Scholar
PubMed
Close
,
Jie-Yang Jhuang Department of Pathology, MacKay Memorial Hospital and Mackay Medical College, Taipei, Taiwan

Search for other papers by Jie-Yang Jhuang in
Google Scholar
PubMed
Close
,
Yi-Chiung Hsu Department of Biomedical Sciences and Engineering, National Central University, Taoyuan City, Taiwan

Search for other papers by Yi-Chiung Hsu in
Google Scholar
PubMed
Close
,
Shih-Yuan Huang Department of Medical Research, MacKay Memorial Hospital, Taipei, Taiwan

Search for other papers by Shih-Yuan Huang in
Google Scholar
PubMed
Close
, and
Shih-Ping Cheng Department of Surgery, MacKay Memorial Hospital and Mackay Medical College, Taipei, Taiwan
Department of Medical Research, MacKay Memorial Hospital, Taipei, Taiwan
Department of Pharmacology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan

Search for other papers by Shih-Ping Cheng in
Google Scholar
PubMed
Close

) in complete media and incubated at 37°C for up to 10 days. The medium was replaced every 3–4 days. Cell migration and invasion assays Cell migration assays were performed using Transwell chambers with a pore size of 8 μm (Corning). For the

Restricted access
Sun Wook Cho Department of Internal Medicine, Department of Pathology, Lee Gil Ya Cancer and Diabetes Institute, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul 03080, South Korea

Search for other papers by Sun Wook Cho in
Google Scholar
PubMed
Close
,
Young A Kim Department of Internal Medicine, Department of Pathology, Lee Gil Ya Cancer and Diabetes Institute, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul 03080, South Korea

Search for other papers by Young A Kim in
Google Scholar
PubMed
Close
,
Hyun Jin Sun Department of Internal Medicine, Department of Pathology, Lee Gil Ya Cancer and Diabetes Institute, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul 03080, South Korea

Search for other papers by Hyun Jin Sun in
Google Scholar
PubMed
Close
,
Ye An Kim Department of Internal Medicine, Department of Pathology, Lee Gil Ya Cancer and Diabetes Institute, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul 03080, South Korea

Search for other papers by Ye An Kim in
Google Scholar
PubMed
Close
,
Byung-Chul Oh Department of Internal Medicine, Department of Pathology, Lee Gil Ya Cancer and Diabetes Institute, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul 03080, South Korea

Search for other papers by Byung-Chul Oh in
Google Scholar
PubMed
Close
,
Ka Hee Yi Department of Internal Medicine, Department of Pathology, Lee Gil Ya Cancer and Diabetes Institute, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul 03080, South Korea

Search for other papers by Ka Hee Yi in
Google Scholar
PubMed
Close
,
Do Joon Park Department of Internal Medicine, Department of Pathology, Lee Gil Ya Cancer and Diabetes Institute, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul 03080, South Korea

Search for other papers by Do Joon Park in
Google Scholar
PubMed
Close
, and
Young Joo Park Department of Internal Medicine, Department of Pathology, Lee Gil Ya Cancer and Diabetes Institute, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul 03080, South Korea

Search for other papers by Young Joo Park in
Google Scholar
PubMed
Close

actions on PTC cell invasiveness and demonstrated bi-directional roles of CXCL16 in macrophage–tumor interactions. Materials and methods Reagents Recombinant human CXCL16, anti-human CXCL16 neutralizing antibody, and human CXCL16 Quantikine ELISA Kit were

Free access
Veronica Kalhori Department of Biosciences, Åbo Akademi University, Turku, Finland
The Minerva Foundation Institute for Medical Research, Biomedicum Helsinki, Helsinki, Finland

Search for other papers by Veronica Kalhori in
Google Scholar
PubMed
Close
,
Melissa Magnusson Department of Biosciences, Åbo Akademi University, Turku, Finland
The Minerva Foundation Institute for Medical Research, Biomedicum Helsinki, Helsinki, Finland

Search for other papers by Melissa Magnusson in
Google Scholar
PubMed
Close
,
Muhammad Yasir Asghar Department of Biosciences, Åbo Akademi University, Turku, Finland

Search for other papers by Muhammad Yasir Asghar in
Google Scholar
PubMed
Close
,
Ilari Pulli Department of Biosciences, Åbo Akademi University, Turku, Finland

Search for other papers by Ilari Pulli in
Google Scholar
PubMed
Close
, and
Kid Törnquist Department of Biosciences, Åbo Akademi University, Turku, Finland
The Minerva Foundation Institute for Medical Research, Biomedicum Helsinki, Helsinki, Finland

Search for other papers by Kid Törnquist in
Google Scholar
PubMed
Close

substantial amount of evidence has implicated S1P in the progression of several types of cancers by enhancing many central events such as proliferation, angiogenesis, migration, and invasion ( Alvarez et al . 2007 , Strub et al . 2010 , Alshaker et al

Free access
Xi Wei Department of Diagnostic and Therapeutic Ultrasonography, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, China

Search for other papers by Xi Wei in
Google Scholar
PubMed
Close
,
Shang Cai Department of Oncology, Southern Research Institute and Cancer Cell Biology Program, the University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham, Alabama, USA
Department of Radiotherapy and Oncology, the Second Affiliated Hospital of Soochow University, Suzhou, China

Search for other papers by Shang Cai in
Google Scholar
PubMed
Close
,
Rebecca J Boohaker Department of Oncology, Southern Research Institute and Cancer Cell Biology Program, the University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham, Alabama, USA

Search for other papers by Rebecca J Boohaker in
Google Scholar
PubMed
Close
,
Joshua Fried Department of Oncology, Southern Research Institute and Cancer Cell Biology Program, the University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham, Alabama, USA

Search for other papers by Joshua Fried in
Google Scholar
PubMed
Close
,
Ying Li The Third Department of Breast Cancer, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, China

Search for other papers by Ying Li in
Google Scholar
PubMed
Close
,
Linfei Hu Department of Thyroid Tumor, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, China

Search for other papers by Linfei Hu in
Google Scholar
PubMed
Close
,
Yi Pan Department of Thyroid Tumor, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, China

Search for other papers by Yi Pan in
Google Scholar
PubMed
Close
,
Ruifen Cheng Department of Thyroid Tumor, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, China

Search for other papers by Ruifen Cheng in
Google Scholar
PubMed
Close
,
Sheng Zhang Department of Diagnostic and Therapeutic Ultrasonography, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, China

Search for other papers by Sheng Zhang in
Google Scholar
PubMed
Close
,
Ye Tian Department of Radiotherapy and Oncology, the Second Affiliated Hospital of Soochow University, Suzhou, China

Search for other papers by Ye Tian in
Google Scholar
PubMed
Close
,
Ming Gao Department of Thyroid Tumor, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center of Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin, China

Search for other papers by Ming Gao in
Google Scholar
PubMed
Close
, and
Bo Xu Department of Oncology, Southern Research Institute and Cancer Cell Biology Program, the University of Alabama at Birmingham Comprehensive Cancer Center, Birmingham, Alabama, USA
Department of Molecular Radiation Oncology, Key Laboratory of Breast Cancer Prevention and Therapy, Ministry of Education, National Clinical Research Center of Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China

Search for other papers by Bo Xu in
Google Scholar
PubMed
Close

Introduction Highly aggressive, anaplastic thyroid cancer (ATC) is a rare form of thyroid cancer with median survival of only ~4 months due to invasive nature and metastatic capacity ( Xing 2013 , Molinaro et al . 2017 ). ATC is typically

Free access
Lidong Wang Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, China

Search for other papers by Lidong Wang in
Google Scholar
PubMed
Close
,
Hao Tan Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, China

Search for other papers by Hao Tan in
Google Scholar
PubMed
Close
,
Yonglian Huang Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, China

Search for other papers by Yonglian Huang in
Google Scholar
PubMed
Close
,
Mingyue Guo Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, China

Search for other papers by Mingyue Guo in
Google Scholar
PubMed
Close
,
Yanxu Dong Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, China

Search for other papers by Yanxu Dong in
Google Scholar
PubMed
Close
,
Chenxi Liu Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, China

Search for other papers by Chenxi Liu in
Google Scholar
PubMed
Close
,
Huai Zhao Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, China

Search for other papers by Huai Zhao in
Google Scholar
PubMed
Close
, and
Zhen Liu Department of General Surgery, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, China

Search for other papers by Zhen Liu in
Google Scholar
PubMed
Close

cultured in a medium containing 2% FBS and photographed at 0 and 24 h in the same visual fields under a phase-contrast microscope. The ImageJ software was used to measure and calculate the percentages of wound closure. Matrigel invasion assay

Restricted access
Bin Li Department of Neurosurgery, Peking University People’s Hospital, Beijing, China

Search for other papers by Bin Li in
Google Scholar
PubMed
Close
,
Sida Zhao Department of Cell and Biology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China

Search for other papers by Sida Zhao in
Google Scholar
PubMed
Close
,
Yiyuan Chen Department of Cell and Biology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China

Search for other papers by Yiyuan Chen in
Google Scholar
PubMed
Close
,
Hua Gao Department of Cell and Biology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China

Search for other papers by Hua Gao in
Google Scholar
PubMed
Close
,
Weiyan Xie Department of Cell and Biology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China

Search for other papers by Weiyan Xie in
Google Scholar
PubMed
Close
,
Hongyun Wang Department of Cell and Biology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China

Search for other papers by Hongyun Wang in
Google Scholar
PubMed
Close
,
Peng Zhao Department of Neurosurgical, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

Search for other papers by Peng Zhao in
Google Scholar
PubMed
Close
,
Chuzhong Li Department of Neurosurgical, Beijing Tiantan Hospital, Capital Medical University, Beijing, China

Search for other papers by Chuzhong Li in
Google Scholar
PubMed
Close
, and
Yazhuo Zhang Department of Cell and Biology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China

Search for other papers by Yazhuo Zhang in
Google Scholar
PubMed
Close

Introduction Pituitary neuroendocrine tumors (PitNETs) are common intracranial benign tumors. About 25–55% of PitNETs exhibit invasive performance, characterized by invading adjacent structures, including cavernous sinus (CS), sphenoid sinus

Restricted access
Avaniyapuram Kannan Murugan Division of Molecular Endocrinology, Department of Molecular Oncology, King Faisal, Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

Search for other papers by Avaniyapuram Kannan Murugan in
Google Scholar
PubMed
Close
,
Abeer Al-Amr Department of Microbiology, College of Science, Female Campus, King Saud University, Riyadh, Saudi Arabia

Search for other papers by Abeer Al-Amr in
Google Scholar
PubMed
Close
,
Mysoon M Al-Ansari Department of Microbiology, College of Science, Female Campus, King Saud University, Riyadh, Saudi Arabia
Department of Molecular Oncology, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

Search for other papers by Mysoon M Al-Ansari in
Google Scholar
PubMed
Close
,
Pulicat S Manogaran Department of Stem Cell Tissue Re-Engineering Program, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

Search for other papers by Pulicat S Manogaran in
Google Scholar
PubMed
Close
,
Hindi Al-Hindi Department of Pathology and Laboratory Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

Search for other papers by Hindi Al-Hindi in
Google Scholar
PubMed
Close
, and
Ali S Alzahrani Division of Molecular Endocrinology, Department of Molecular Oncology, King Faisal, Specialist Hospital and Research Centre, Riyadh, Saudi Arabia
Department of Medicine, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

Search for other papers by Ali S Alzahrani in
Google Scholar
PubMed
Close

characteristics of thyroid cancer and a high rate of recurrence ( Liu et al. 2013 , 2014 , Xing et al. 2014 ). Yet, some cases with BRAF V600E and without any of the above factors display highly invasive and metastatic phenotypes suggesting that there may

Restricted access
Annu Makker Post Graduate Department of Pathology, King George's Medical University, Lucknow 226003, Uttar Pradesh, India

Search for other papers by Annu Makker in
Google Scholar
PubMed
Close
and
Madhu Mati Goel Post Graduate Department of Pathology, King George's Medical University, Lucknow 226003, Uttar Pradesh, India

Search for other papers by Madhu Mati Goel in
Google Scholar
PubMed
Close

. Atypical endometrial hyperplasia (AEH) has been reported to be associated with invasive EC in 62% endometrial biopsy specimens, suggesting that AEH may be the direct precursor to endometrioid EC (EEC; Amant et al . 2005 , Trimble et al . 2006 ). EEC

Free access
Haleh Vosgha Cancer Molecular Pathology, School of Medicine, Menzies Health Institute Queensland, Griffith University, Gold Coast, Queensland, Australia

Search for other papers by Haleh Vosgha in
Google Scholar
PubMed
Close
,
Armin Ariana Cancer Molecular Pathology, School of Medicine, Menzies Health Institute Queensland, Griffith University, Gold Coast, Queensland, Australia

Search for other papers by Armin Ariana in
Google Scholar
PubMed
Close
,
Robert Anthony Smith Cancer Molecular Pathology, School of Medicine, Menzies Health Institute Queensland, Griffith University, Gold Coast, Queensland, Australia
Genomics Research Centre, Institute of Health and Biomedical Innovation, Faculty of Health, Queensland University of Technology, Brisbane, Queensland, Australia

Search for other papers by Robert Anthony Smith in
Google Scholar
PubMed
Close
, and
Alfred King-yin Lam Cancer Molecular Pathology, School of Medicine, Menzies Health Institute Queensland, Griffith University, Gold Coast, Queensland, Australia

Search for other papers by Alfred King-yin Lam in
Google Scholar
PubMed
Close

promoting angiogenesis have been suggested ( Sang 1998 , Hoeben et al . 2004 , Araujo et al . 2015 ). The interactions of these proteins and their potential roles in the invasive behaviour of anaplastic thyroid carcinoma are yet to be addressed properly

Free access
Meenu Jain Endocrine Oncology Branch, National Center for Advancing Translational Sciences, National Cancer Institute

Search for other papers by Meenu Jain in
Google Scholar
PubMed
Close
,
Lisa Zhang Endocrine Oncology Branch, National Center for Advancing Translational Sciences, National Cancer Institute

Search for other papers by Lisa Zhang in
Google Scholar
PubMed
Close
,
Mei He Endocrine Oncology Branch, National Center for Advancing Translational Sciences, National Cancer Institute

Search for other papers by Mei He in
Google Scholar
PubMed
Close
,
Ya-Qin Zhang Endocrine Oncology Branch, National Center for Advancing Translational Sciences, National Cancer Institute

Search for other papers by Ya-Qin Zhang in
Google Scholar
PubMed
Close
,
Min Shen Endocrine Oncology Branch, National Center for Advancing Translational Sciences, National Cancer Institute

Search for other papers by Min Shen in
Google Scholar
PubMed
Close
, and
Electron Kebebew Endocrine Oncology Branch, National Center for Advancing Translational Sciences, National Cancer Institute

Search for other papers by Electron Kebebew in
Google Scholar
PubMed
Close

. Using siRNA knockdown of TOP2A in ACC cell lines, we found that it regulates cellular proliferation and invasion. Given the consistent overexpression of TOP2A in ACC, we tested 14 TOP2A inhibitors for their antiproliferative effect and found that

Free access