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D Deandreis Department of Nuclear Medicine and Endocrine Oncology, Department of Pathology and Clinical Biology, Unit 605, National Institute of Health and Medical Research, Institut Gustave Roussy and University Paris Sud, 39 Rue Camille Desmoulins, 94805 Villejuif, France

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A Al Ghuzlan Department of Nuclear Medicine and Endocrine Oncology, Department of Pathology and Clinical Biology, Unit 605, National Institute of Health and Medical Research, Institut Gustave Roussy and University Paris Sud, 39 Rue Camille Desmoulins, 94805 Villejuif, France

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S Leboulleux Department of Nuclear Medicine and Endocrine Oncology, Department of Pathology and Clinical Biology, Unit 605, National Institute of Health and Medical Research, Institut Gustave Roussy and University Paris Sud, 39 Rue Camille Desmoulins, 94805 Villejuif, France

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L Lacroix Department of Nuclear Medicine and Endocrine Oncology, Department of Pathology and Clinical Biology, Unit 605, National Institute of Health and Medical Research, Institut Gustave Roussy and University Paris Sud, 39 Rue Camille Desmoulins, 94805 Villejuif, France

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J P Garsi Department of Nuclear Medicine and Endocrine Oncology, Department of Pathology and Clinical Biology, Unit 605, National Institute of Health and Medical Research, Institut Gustave Roussy and University Paris Sud, 39 Rue Camille Desmoulins, 94805 Villejuif, France

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M Talbot Department of Nuclear Medicine and Endocrine Oncology, Department of Pathology and Clinical Biology, Unit 605, National Institute of Health and Medical Research, Institut Gustave Roussy and University Paris Sud, 39 Rue Camille Desmoulins, 94805 Villejuif, France

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J Lumbroso Department of Nuclear Medicine and Endocrine Oncology, Department of Pathology and Clinical Biology, Unit 605, National Institute of Health and Medical Research, Institut Gustave Roussy and University Paris Sud, 39 Rue Camille Desmoulins, 94805 Villejuif, France

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E Baudin Department of Nuclear Medicine and Endocrine Oncology, Department of Pathology and Clinical Biology, Unit 605, National Institute of Health and Medical Research, Institut Gustave Roussy and University Paris Sud, 39 Rue Camille Desmoulins, 94805 Villejuif, France

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B Caillou Department of Nuclear Medicine and Endocrine Oncology, Department of Pathology and Clinical Biology, Unit 605, National Institute of Health and Medical Research, Institut Gustave Roussy and University Paris Sud, 39 Rue Camille Desmoulins, 94805 Villejuif, France

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J M Bidart Department of Nuclear Medicine and Endocrine Oncology, Department of Pathology and Clinical Biology, Unit 605, National Institute of Health and Medical Research, Institut Gustave Roussy and University Paris Sud, 39 Rue Camille Desmoulins, 94805 Villejuif, France

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M Schlumberger Department of Nuclear Medicine and Endocrine Oncology, Department of Pathology and Clinical Biology, Unit 605, National Institute of Health and Medical Research, Institut Gustave Roussy and University Paris Sud, 39 Rue Camille Desmoulins, 94805 Villejuif, France

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by the number of mitoses ( Akslen & LiVolsi 2000 , Hiltzik et al . 2006 ). Furthermore, immunohistochemistry may detect the expression of proteins involved in iodine metabolism (sodium iodine symporter (NIS), thyroglobulin (Tg), thyroid peroxidase

Article Type:
Research Article
DOI:
https://doi.org/10.1677/ERC-10-0233
Volume/Issue:
Volume 18: Issue 1
Free access
Ofelia Soriano
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Guadalupe Delgado
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Brenda Anguiano
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Pavel Petrosyan Instituto de Neurobiología, Instituto de Investigaciones Biomédicas, Campus Juriquilla, Universidad Nacional Autónoma de México, Querétaro, Mexico

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Edith D Molina-Servín Instituto de Neurobiología, Instituto de Investigaciones Biomédicas, Campus Juriquilla, Universidad Nacional Autónoma de México, Querétaro, Mexico

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Maria E Gonsebatt Instituto de Neurobiología, Instituto de Investigaciones Biomédicas, Campus Juriquilla, Universidad Nacional Autónoma de México, Querétaro, Mexico

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Carmen Aceves
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quantification. Values are expressed as mean± s.d . Means with different letters are significantly different ( P <0.05). To explore the effect of iodine supplement on the proteins needed for the uptake and metabolism of iodine, we measured the expression of NIS

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-11-0065
Volume/Issue:
Volume 18: Issue 4
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Patricia Borges de Souza Department of Medical Sciences, Section of Endocrinology and Internal Medicine, University of Ferrara, Ferrara, Emilia-Romagna, Italy

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Christopher John McCabe Institute of Metabolism and Systems Research, Birmingham Health Partners, University of Birmingham, Birmingham, UK

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’s lecture was a select group of clinicians and scientists interested in iodine metabolism. They included Saul Hertz, then Director of The Massachusetts General Hospital (MGH)’s Thyroid Unit, Earl Chapman, a private doctor who worked part-time at MGH, and

Article Type:
Review Article
DOI:
https://doi.org/10.1530/ERC-21-0037
Volume/Issue:
Volume 28: Issue 10
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Fernanda Vaisman
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Denise P Carvalho Endocrinology Service, Laboratório de Fosiologia Endócrina Doris Rosental, Endocrinology Service, National Cancer Institute, Brazil Praça da Cruz Vermelha, 23, 8° Floor, Centro, Rio de Janeiro, Rio de Janeiro, 20230-130, Brazil

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Mario Vaisman Endocrinology Service, Laboratório de Fosiologia Endócrina Doris Rosental, Endocrinology Service, National Cancer Institute, Brazil Praça da Cruz Vermelha, 23, 8° Floor, Centro, Rio de Janeiro, Rio de Janeiro, 20230-130, Brazil

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-called flip–flop phenomenon describes the condition of when the tumor is no longer able to uptake iodine or this uptake is low and lesions are FDG-avid due to intense glucose uptake and metabolism. These tumors tend to be larger, more invasive ( Esteva et al

Article Type:
Review Article
DOI:
https://doi.org/10.1530/ERC-15-0300
Volume/Issue:
Volume 22: Issue 6
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Sarah E Mayson Division of Endocrinology, Metabolism and Diabetes, University of Colorado School of Medicine, Aurora, Colorado, USA

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Christine M Chan Section of Endocrinology, Department of Pediatrics, Children’s Hospital Colorado, University of Colorado School of Medicine, Aurora, Colorado, USA

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Bryan R Haugen Division of Endocrinology, Metabolism and Diabetes, University of Colorado School of Medicine, Aurora, Colorado, USA
University of Colorado Cancer Center, Aurora, Colorado, USA

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JA Burns JA 2002 Nasolacrimal drainage system obstruction from radioactive iodine therapy for thyroid carcinoma . Journal of Clinical Endocrinology and Metabolism 87 5817 – 5820 . ( https://doi.org/10.1210/jc.2002-020210 ) Klubo

Article Type:
Review Article
DOI:
https://doi.org/10.1530/ERC-21-0161
Volume/Issue:
Volume 28: Issue 10
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C Nascimento
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I Borget Department of Nuclear Medicine and Endocrine Oncology, Statistic and Epidemiology, Medical Biology and Pathology, Radiology, Surgery, Institut Gustave Roussy, Univ. Paris-Sud, 39 rue Camille Desmoulins, 94805 Villejuif Cedex, France Departments of

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A Al Ghuzlan Department of Nuclear Medicine and Endocrine Oncology, Statistic and Epidemiology, Medical Biology and Pathology, Radiology, Surgery, Institut Gustave Roussy, Univ. Paris-Sud, 39 rue Camille Desmoulins, 94805 Villejuif Cedex, France Departments of

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D Deandreis
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L Chami Department of Nuclear Medicine and Endocrine Oncology, Statistic and Epidemiology, Medical Biology and Pathology, Radiology, Surgery, Institut Gustave Roussy, Univ. Paris-Sud, 39 rue Camille Desmoulins, 94805 Villejuif Cedex, France Departments of

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J P Travagli Department of Nuclear Medicine and Endocrine Oncology, Statistic and Epidemiology, Medical Biology and Pathology, Radiology, Surgery, Institut Gustave Roussy, Univ. Paris-Sud, 39 rue Camille Desmoulins, 94805 Villejuif Cedex, France Departments of

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D Hartl Department of Nuclear Medicine and Endocrine Oncology, Statistic and Epidemiology, Medical Biology and Pathology, Radiology, Surgery, Institut Gustave Roussy, Univ. Paris-Sud, 39 rue Camille Desmoulins, 94805 Villejuif Cedex, France Departments of

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J Lumbroso
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C Chougnet
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L Lacroix Department of Nuclear Medicine and Endocrine Oncology, Statistic and Epidemiology, Medical Biology and Pathology, Radiology, Surgery, Institut Gustave Roussy, Univ. Paris-Sud, 39 rue Camille Desmoulins, 94805 Villejuif Cedex, France Departments of

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E Baudin
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M Schlumberger
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S Leboulleux
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.2008-1931 . Cailleux AF Baudin E Travagli JP Ricard M Schlumberger M 2000 Is diagnostic iodine-131 scanning useful after total thyroid ablation for differentiated thyroid cancer? Journal of Clinical Endocrinology and Metabolism 85

Article Type:
Research Article
DOI:
https://doi.org/10.1677/ERC-10-0292
Volume/Issue:
Volume 18: Issue 2
Free access
Kristien Boelaert Reader in Endocrinology, Institute of Metabolism and Systems Research, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK
Centre for Endocrinology, Diabetes and Metabolism, Birmingham Health Partners, Birmingham, UK

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,329 person-years of follow-up. Journal of Clinical Endocrinology and Metabolism 99 2834 – 2843 . ( doi:10.1210/jc.2013-2118 ) Monahan M Boelaert K Jolly K Chan S Barton P Roberts TE 2015 Costs and benefits of iodine

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Other
DOI:
https://doi.org/10.1530/ERC-16-0396
Volume/Issue:
Volume 23: Issue 11
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Sissy M Jhiang Department of Physiology and Cell Biology, The Ohio State University Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, USA
Department of Internal Medicine, Division of Endocrinology and Metabolism, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA

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Jennifer A Sipos Department of Internal Medicine, Division of Endocrinology and Metabolism, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA

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obstruction from radioactive iodine therapy for thyroid carcinoma . Journal of Clinical Endocrinology and Metabolism 87 5817 – 58 20 . ( https://doi.org/10.1210/jc.2002-020210 ) Knostman KA Cho JY Ryu KY Lin X McCubrey JA Hla T Liu CH Di

Article Type:
Review Article
DOI:
https://doi.org/10.1530/ERC-21-0035
Volume/Issue:
Volume 28: Issue 10
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Livia Lamartina Gustave Roussy, Department of Nuclear Medicine and Endocrine Oncology, Villejuif, France

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Nadège Anizan Department of Medical Physics, Gustave Roussy and University Paris Saclay, Villejuif, France

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Corinne Dupuy UMR 8200/9019 CNRS Paris-Saclay, Genome Integrity and Cancers, Gustave Roussy and University Paris Saclay, Villejuif, France

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Sophie Leboulleux Gustave Roussy, Department of Nuclear Medicine and Endocrine Oncology, Villejuif, France

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Martin Schlumberger Gustave Roussy, Department of Nuclear Medicine and Endocrine Oncology, Villejuif, France

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impairment of iodine metabolism. The life expectancy in these refractory patients can be as low as <10% in 10 years ( Durante et al. 2006 , Schlumberger et al. 2014 ) and they might need other treatment modalities. The improved knowledge on the biology

Article Type:
Review Article
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DOI:
https://doi.org/10.1530/ERC-21-0024
Volume/Issue:
Volume 28: Issue 10
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Antonio De la Vieja Tumor Endocrine Unit, Chronic Disease Program (UFIEC), Instituto de Salud Carlos III, Madrid, Spain
CiberOnc, Instituto de Salud Carlos III, Madrid, Spain

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Pilar Santisteban CiberOnc, Instituto de Salud Carlos III, Madrid, Spain
Department of Physiopathology of Endocrine a Nervous System, Instituto de Investigaciones Biomédicas ‘Alberto Sols’, Consejo Superior de Investigaciones Científicas and Universidad Autónoma de Madrid (CSIC-UAM), Madrid, Spain

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iodine-containing products such as thyroid hormones (THs). In turn, these hormones are critical for life in all vertebrates and have essential roles in development, growth, metamorphosis and metabolism. The reducing properties of I − also make it an

Article Type:
Review Article
DOI:
https://doi.org/10.1530/ERC-17-0515
Volume/Issue:
Volume 25: Issue 4
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