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Nicole Panarelli
Nicole Panarelli
Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, New York, USA
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Kathrin Tyryshkin
Kathrin Tyryshkin
Laboratory of Translational RNA Biology, Department of Pathology and Molecular Medicine, Queen’s University, Kingston, Ontario, Canada
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Justin Jong Mun Wong
Justin Jong Mun Wong
Laboratory of Translational RNA Biology, Department of Pathology and Molecular Medicine, Queen’s University, Kingston, Ontario, Canada
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Adrianna Majewski
Adrianna Majewski
Laboratory of Translational RNA Biology, Department of Pathology and Molecular Medicine, Queen’s University, Kingston, Ontario, Canada
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Xiaojing Yang
Xiaojing Yang
Laboratory of Translational RNA Biology, Department of Pathology and Molecular Medicine, Queen’s University, Kingston, Ontario, Canada
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Theresa Scognamiglio
Theresa Scognamiglio
Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, New York, USA
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Michelle Kang Kim
Michelle Kang Kim
Center for Carcinoid and Neuroendocrine Tumors of Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, New York, USA
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Kimberly Bogardus
Kimberly Bogardus
HHMI, Laboratory of RNA Molecular Biology, The Rockefeller University, New York, New York, USA
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Thomas Tuschl
Thomas Tuschl
HHMI, Laboratory of RNA Molecular Biology, The Rockefeller University, New York, New York, USA
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Yao-Tseng Chen
Yao-Tseng Chen
Department of Pathology and Laboratory Medicine, Weill Cornell Medicine, New York, New York, USA
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Neil Renwick
Neil Renwick
Laboratory of Translational RNA Biology, Department of Pathology and Molecular Medicine, Queen’s University, Kingston, Ontario, Canada
HHMI, Laboratory of RNA Molecular Biology, The Rockefeller University, New York, New York, USA
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HHMI, Laboratory of RNA Molecular Biology, The Rockefeller University, New York, New York, USA
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Introduction Gastroenteropancreatic neuroendocrine tumors (GEP-NETs) are increasingly common and clinically diverse neoplasms ( Yao et al . 2008 , Lawrence et al . 2011 ) that are challenging to evaluate histologically ( Klimstra 2016
Sarah B Bateni
Sarah B Bateni
Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
University of Alabama at Birmingham, Department of Surgery, Division of Surgical Oncology, Birmingham, Alabama, USA
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University of Alabama at Birmingham, Department of Surgery, Division of Surgical Oncology, Birmingham, Alabama, USA
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Natalie G Coburn
Natalie G Coburn
Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
Susan Leslie Clinic for Neuroendocrine Tumors, Odette Cancer Centre - Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Clinical evaluative sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada
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Susan Leslie Clinic for Neuroendocrine Tumors, Odette Cancer Centre - Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Clinical evaluative sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada
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Calvin Law
Calvin Law
Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
Susan Leslie Clinic for Neuroendocrine Tumors, Odette Cancer Centre - Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
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Susan Leslie Clinic for Neuroendocrine Tumors, Odette Cancer Centre - Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
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Simron Singh
Simron Singh
Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
Susan Leslie Clinic for Neuroendocrine Tumors, Odette Cancer Centre - Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Clinical evaluative sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada
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Susan Leslie Clinic for Neuroendocrine Tumors, Odette Cancer Centre - Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Clinical evaluative sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada
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Sten Myrehaug
Sten Myrehaug
Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
Susan Leslie Clinic for Neuroendocrine Tumors, Odette Cancer Centre - Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Clinical evaluative sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada
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Susan Leslie Clinic for Neuroendocrine Tumors, Odette Cancer Centre - Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Clinical evaluative sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada
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Angela Assal
Angela Assal
Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
Susan Leslie Clinic for Neuroendocrine Tumors, Odette Cancer Centre - Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Clinical evaluative sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada
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Susan Leslie Clinic for Neuroendocrine Tumors, Odette Cancer Centre - Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Clinical evaluative sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada
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Julie Hallet
Julie Hallet
Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada
Susan Leslie Clinic for Neuroendocrine Tumors, Odette Cancer Centre - Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Clinical evaluative sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada
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Susan Leslie Clinic for Neuroendocrine Tumors, Odette Cancer Centre - Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
Clinical evaluative sciences, Sunnybrook Research Institute, Toronto, Ontario, Canada
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Introduction Neuroendocrine tumors (NETs) are rare tumors originating from the neuroendocrine system along the gastrointestinal tract and lungs ( Yao et al. 2008 , Hallet et al. 2015 , Dasari et al. 2017 , 2018 ). Although
Chiara Alessandra Cella
Chiara Alessandra Cella
Division of Gastrointestinal Medical Oncology and Neuroendocrine Tumors, European Institute of Oncology, IEO, IRCCS, Milan, Italy
Department of Molecular and Translational Medicine, Division of Biology and Genetics, University of Brescia, Brescia, Italy
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Department of Molecular and Translational Medicine, Division of Biology and Genetics, University of Brescia, Brescia, Italy
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Riccardo Cazzoli
Riccardo Cazzoli
Department of Experimental Oncology, European Institute of Oncology, IEO, IRCCS, Milan, Italy
Metal Targeted Therapy & Immunology lab, Childrens’ cancer institute, Sydney, NSW, Australia
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Metal Targeted Therapy & Immunology lab, Childrens’ cancer institute, Sydney, NSW, Australia
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Nicola Fazio
Nicola Fazio
Division of Gastrointestinal Medical Oncology and Neuroendocrine Tumors, European Institute of Oncology, IEO, IRCCS, Milan, Italy
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Giuseppina De Petro
Giuseppina De Petro
Department of Molecular and Translational Medicine, Division of Biology and Genetics, University of Brescia, Brescia, Italy
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Germano Gaudenzi
Germano Gaudenzi
Laboratory of Geriatric and Oncologic Neuroendocrinology Research, IRCCS, Istituto Auxologico Italiano, Milan, Italy
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Silvia Carra
Silvia Carra
Laboratory of Endocrine and Metabolic Research, IRCCS, Istituto Auxologico Italiano, Milan, Italy
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Mauro Romanenghi
Mauro Romanenghi
Department of Experimental Oncology, European Institute of Oncology, IEO, IRCCS, Milan, Italy
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Francesca Spada
Francesca Spada
Division of Gastrointestinal Medical Oncology and Neuroendocrine Tumors, European Institute of Oncology, IEO, IRCCS, Milan, Italy
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Ilaria Grossi
Ilaria Grossi
Department of Molecular and Translational Medicine, Division of Biology and Genetics, University of Brescia, Brescia, Italy
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Isabella Pallavicini
Isabella Pallavicini
Department of Experimental Oncology, European Institute of Oncology, IEO, IRCCS, Milan, Italy
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Saverio Minucci
Saverio Minucci
Department of Experimental Oncology, European Institute of Oncology, IEO, IRCCS, Milan, Italy
Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy
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Department of Oncology and Hemato-Oncology, University of Milan, Milan, Italy
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Giovanni Vitale
Giovanni Vitale
Laboratory of Geriatric and Oncologic Neuroendocrinology Research, IRCCS, Istituto Auxologico Italiano, Milan, Italy
Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy
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Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy
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tumors (NETs), to be distinguished from neuroendocrine carcinomas (NECs) which are the poorly differentiated or high-grade forms. NETs have a variety of biological and clinical behaviors and are known to be highly vascularized. Accumulating knowledge
Elke Tatjana Aristizabal Prada
Elke Tatjana Aristizabal Prada
Interdisciplinary Center of Neuroendocrine Tumors of the GastroEnteroPancreatic System (GEPNET-KUM), Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Campus Grosshadern, Munich, Germany
Department of Internal Medicine 2, University-Hospital, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Munich, Germany
Department of Internal Medicine 4, University-Hospital, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Munich, Germany
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Department of Internal Medicine 2, University-Hospital, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Munich, Germany
Department of Internal Medicine 4, University-Hospital, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Munich, Germany
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Vera Heinzle
Vera Heinzle
Interdisciplinary Center of Neuroendocrine Tumors of the GastroEnteroPancreatic System (GEPNET-KUM), Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Campus Grosshadern, Munich, Germany
Department of Internal Medicine 2, University-Hospital, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Munich, Germany
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Department of Internal Medicine 2, University-Hospital, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Munich, Germany
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Thomas Knösel
Thomas Knösel
Interdisciplinary Center of Neuroendocrine Tumors of the GastroEnteroPancreatic System (GEPNET-KUM), Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Campus Grosshadern, Munich, Germany
Institute of Pathology, Ludwig-Maximilians-University of Munich, Munich, Germany
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Institute of Pathology, Ludwig-Maximilians-University of Munich, Munich, Germany
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Svenja Nölting
Svenja Nölting
Interdisciplinary Center of Neuroendocrine Tumors of the GastroEnteroPancreatic System (GEPNET-KUM), Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Campus Grosshadern, Munich, Germany
Department of Internal Medicine 2, University-Hospital, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Munich, Germany
Department of Internal Medicine 4, University-Hospital, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Munich, Germany
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Department of Internal Medicine 2, University-Hospital, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Munich, Germany
Department of Internal Medicine 4, University-Hospital, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Munich, Germany
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Gerald Spöttl
Gerald Spöttl
Interdisciplinary Center of Neuroendocrine Tumors of the GastroEnteroPancreatic System (GEPNET-KUM), Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Campus Grosshadern, Munich, Germany
Department of Internal Medicine 2, University-Hospital, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Munich, Germany
Department of Internal Medicine 4, University-Hospital, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Munich, Germany
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Department of Internal Medicine 2, University-Hospital, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Munich, Germany
Department of Internal Medicine 4, University-Hospital, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Munich, Germany
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Julian Maurer
Julian Maurer
Interdisciplinary Center of Neuroendocrine Tumors of the GastroEnteroPancreatic System (GEPNET-KUM), Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Campus Grosshadern, Munich, Germany
Department of Internal Medicine 2, University-Hospital, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Munich, Germany
Department of Internal Medicine 4, University-Hospital, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Munich, Germany
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Department of Internal Medicine 2, University-Hospital, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Munich, Germany
Department of Internal Medicine 4, University-Hospital, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Munich, Germany
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Christine Spitzweg
Christine Spitzweg
Interdisciplinary Center of Neuroendocrine Tumors of the GastroEnteroPancreatic System (GEPNET-KUM), Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Campus Grosshadern, Munich, Germany
Department of Internal Medicine 2, University-Hospital, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Munich, Germany
Department of Internal Medicine 4, University-Hospital, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Munich, Germany
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Department of Internal Medicine 2, University-Hospital, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Munich, Germany
Department of Internal Medicine 4, University-Hospital, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Munich, Germany
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Martin Angele
Martin Angele
Interdisciplinary Center of Neuroendocrine Tumors of the GastroEnteroPancreatic System (GEPNET-KUM), Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Campus Grosshadern, Munich, Germany
Department of General, Visceral, Transplantation, Vascular and Thoracic Surgery, University-Hospital, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Munich, Germany
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Department of General, Visceral, Transplantation, Vascular and Thoracic Surgery, University-Hospital, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Munich, Germany
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Nina Schmidt
Nina Schmidt
Interdisciplinary Center of Neuroendocrine Tumors of the GastroEnteroPancreatic System (GEPNET-KUM), Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Campus Grosshadern, Munich, Germany
Department of Internal Medicine 2, University-Hospital, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Munich, Germany
Department of Internal Medicine 4, University-Hospital, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Munich, Germany
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Department of Internal Medicine 2, University-Hospital, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Munich, Germany
Department of Internal Medicine 4, University-Hospital, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Munich, Germany
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Felix Beuschlein
Felix Beuschlein
Department of Internal Medicine 4, University-Hospital, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Munich, Germany
Klinik für Endokrinologie, Diabetologie und Klinische Ernährung, Universitätsspital Zürich, Zurich, Switzerland
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Klinik für Endokrinologie, Diabetologie und Klinische Ernährung, Universitätsspital Zürich, Zurich, Switzerland
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Günter K Stalla
Günter K Stalla
Clinical Neuroendocrinology, Max Planck Institute of Psychiatry, Munich, Germany
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Rainer Blaser
Rainer Blaser
Institute of Medical Statistics and Epidemiology, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany
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Klaus A Kuhn
Klaus A Kuhn
Institute of Medical Statistics and Epidemiology, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany
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Christoph J Auernhammer
Christoph J Auernhammer
Interdisciplinary Center of Neuroendocrine Tumors of the GastroEnteroPancreatic System (GEPNET-KUM), Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Campus Grosshadern, Munich, Germany
Department of Internal Medicine 2, University-Hospital, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Munich, Germany
Department of Internal Medicine 4, University-Hospital, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Munich, Germany
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Department of Internal Medicine 2, University-Hospital, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Munich, Germany
Department of Internal Medicine 4, University-Hospital, Klinikum der Universität München, Ludwig-Maximilians-University of Munich, Munich, Germany
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Introduction Neuroendocrine tumors (NETs) are highly heterogeneous tumors originating from distinct cell precursors ( Schimmack et al . 2011 ). Current data show an increase in incidence of gastroenteropancreatic neuroendocrine tumors (GEP
Germano Gaudenzi
Germano Gaudenzi
Istituto Auxologico Italiano, IRCCS, Laboratorio Sperimentale di Ricerche di Neuroendocrinologia Geriatrica ed Oncologica, Milan, Italy
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Silvia Carra
Silvia Carra
Istituto Auxologico Italiano, IRCCS, Laboratorio Sperimentale di Ricerche Endocrino-Metaboliche, Milan, Italy
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Alessandra Dicitore
Alessandra Dicitore
Department of Clinical Sciences and Community Health (DISCCO), University of Milan, Milan, Italy
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Maria Celeste Cantone
Maria Celeste Cantone
Department of Clinical Sciences and Community Health (DISCCO), University of Milan, Milan, Italy
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Luca Persani
Luca Persani
Istituto Auxologico Italiano, IRCCS, Laboratorio Sperimentale di Ricerche Endocrino-Metaboliche, Milan, Italy
Department of Clinical Sciences and Community Health (DISCCO), University of Milan, Milan, Italy
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Department of Clinical Sciences and Community Health (DISCCO), University of Milan, Milan, Italy
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Giovanni Vitale
Giovanni Vitale
Istituto Auxologico Italiano, IRCCS, Laboratorio Sperimentale di Ricerche di Neuroendocrinologia Geriatrica ed Oncologica, Milan, Italy
Department of Clinical Sciences and Community Health (DISCCO), University of Milan, Milan, Italy
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Department of Clinical Sciences and Community Health (DISCCO), University of Milan, Milan, Italy
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Introduction Neuroendocrine tumors (NETs) represent a broad class of neoplasms originating from neuroendocrine cells. NETs can cause a wide array of symptoms depending on the type of tumor, its location and the production of several factors
Jaydira Del Rivero
Jaydira Del Rivero
Developmental Therapeutics Branch, National Cancer Institute, National Institutes of Health, Bethesda, USA
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Josh Mailman
Josh Mailman
NorCal CarciNET Community, Oakland, California, USA
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Michael W Rabow
Michael W Rabow
Department of Internal Medicine, Division of Palliative Medicine, University of California, San Francisco, San Francisco, California, USA
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Jennifer A Chan
Jennifer A Chan
Harvard Medical School, Program in Carcinoid and Neuroendocrine Tumors, Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA
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Sarah Creed
Sarah Creed
Good Shepherd Community Care, Harvard Kennedy School, Natick, Massachusetts, USA
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Hagen F Kennecke
Hagen F Kennecke
Providence Cancer Institute Franz Clinic, Portland Providence Medical Center, Portland, Oregon, USA
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Janice Pasieka
Janice Pasieka
Department of Surgery, Section of General Surgery, University of Calgary, Cumming School of Medicine, Calgary, Canada
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Jennifer Zuar
Jennifer Zuar
Department of Internal Medicine, Division of Geriatrics and Palliative Medicine, Alpert Medical School, Providence, Rhode Island, USA
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Simron Singh
Simron Singh
Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
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Lauren Fishbein
Lauren Fishbein
Department of Medicine, Division of Endocrinology, Metabolism and Diabetes, Department of Biomedical Informatics, University of Colorado School of Medicine, Aurora, Colorado, USA
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lung cancer ( Temel et al. 2010 , Ferrell et al. 2017 ). Patients with neuroendocrine tumors (NETs) represent a unique population, as many have metastatic disease at presentation, yet can have prolonged survival rates for years. Since these
Tobias Krauss
Tobias Krauss
Department of Radiology, Medical Center – University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany
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Alfonso Massimiliano Ferrara
Alfonso Massimiliano Ferrara
Familial Cancer Clinic and Oncoendocrinology, Veneto Institute of Oncology IOV- IRCCS, Padua, Italy
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Thera P Links
Thera P Links
Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
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Ulrich Wellner
Ulrich Wellner
Department of Surgery, University of Luebeck, Luebeck, Germany
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Irina Bancos
Irina Bancos
Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic, Rochester, USA
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Andrey Kvachenyuk
Andrey Kvachenyuk
Institute of Endocrinology and Metabolism, NAMS of Ukraine, Kiev, Ukraine
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Karina Villar Gómez de las Heras
Karina Villar Gómez de las Heras
Central Services, Servicio de Salud de Castilla-La Mancha (SESCAM), Toledo, Spain
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Marina Y Yukina
Marina Y Yukina
Department of Surgery, Endocrinology Research Center, Moscow, Russia
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Roman Petrov
Roman Petrov
Department of Surgery, Bakhrushin Brothers Moscow City Hospital, Moscow, Russia
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Garrett Bullivant
Garrett Bullivant
Princess Margaret Cancer Center, University Health Network, Toronto, Ontario, Canada
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Laura von Duecker
Laura von Duecker
Department of Medicine IV, Faculty of Medicine, Albert-Ludwigs-University, Freiburg, Germany
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Swati Jadhav
Swati Jadhav
Department of Endocrinology, KEM Hospital, Mumbai, India
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Ursula Ploeckinger
Ursula Ploeckinger
Interdisciplinary Center of Metabolism: Endocrinology, Diabetes and Metabolism, Charité-University Medicine Berlin, Campus Virchow-Klinikum, Berlin, Germany
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Staffan Welin
Staffan Welin
Department of Endocrine Oncology, Uppsala University Hospital, Uppsala, Sweden
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Camilla Schalin-Jäntti
Camilla Schalin-Jäntti
Endocrinology, Abdominal Center, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
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Oliver Gimm
Oliver Gimm
Department of Clinical and Experimental Medicine, Department of Surgery, University of Linköping, Linköping, Sweden
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Marija Pfeifer
Marija Pfeifer
Department of Endocrinology, University Medical Center, Ljubljana, Slovenia
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Joanne Ngeow
Joanne Ngeow
Cancer Genetics Service, Division of Medical Oncology, National Cancer Center Singapore and Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore
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Kornelia Hasse-Lazar
Kornelia Hasse-Lazar
Department of Endocrine Oncology and Nuclear Medicine, Center of Oncology, MSC Memorial Institute, Gliwice, Poland
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Gabriela Sansó
Gabriela Sansó
Centro de Investigaciones Endocrinológicas “Dr Cesar Bergada” (CEDIE), Hospital de Niños Ricardo Gutiérrez, CABA, Buenos Aires, Argentina
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Xiaoping Qi
Xiaoping Qi
Department of Oncologic and Urologic Surgery, the 117th PLA Hospital, Wenzhou Medical University, Hangzhou, Peoples Republic of China
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M Umit Ugurlu
M Umit Ugurlu
Department of General Surgery, Breast and Endocrine Surgery Unit, Marmara University School of Medicine, Istanbul, Turkey
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Rene E Diaz
Rene E Diaz
Endocrine Section, Hospital del Salvador, Santiago de Chile, Chile
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Nelson Wohllk
Nelson Wohllk
Department of Medicine, Endocrine Section, Hospital del Salvador, University of Chile, Santiago de Chile, Chile
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Mariola Peczkowska
Mariola Peczkowska
Department of Hypertension, Institute of Cardiology, Warsaw, Poland
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Jens Aberle
Jens Aberle
3rd Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
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Delmar M Lourenço Jr
Delmar M Lourenço Jr
Serviço de Endocrinologia, Hospital das Clínicas (HCFMUSP) and Instituto do Cancer do Estado de São Paulo (ICESP), Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil
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Maria A A Pereira
Maria A A Pereira
Serviço de Endocrinologia, Hospital das Clinicas (HCFMUSP), Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil
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Maria C B V Fragoso
Maria C B V Fragoso
Serviço de Endocrinologia, Hospital das Clínicas (HCFMUSP) and Instituto do Cancer do Estado de São Paulo (ICESP), Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil
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Ana O Hoff
Ana O Hoff
Serviço de Endocrinologia, Hospital das Clínicas (HCFMUSP) and Instituto do Cancer do Estado de São Paulo (ICESP), Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil
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Madson Q Almeida
Madson Q Almeida
Serviço de Endocrinologia, Hospital das Clínicas (HCFMUSP) and Instituto do Cancer do Estado de São Paulo (ICESP), Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil
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Alice H D Violante
Alice H D Violante
Department of Internal Medicine-Endocrinology, Faculty of medicine-Hospital Universitario Clementino Fraga Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
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Ana R P Quidute
Ana R P Quidute
Department of Physiology and Pharmacology, Drug Research and Development Center (NPDM), Faculty of Medicine, Federal University of Ceará (UFC), Fortaleza, Brazil
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Zhewei Zhang
Zhewei Zhang
Department of Urology, 2nd Hospital of Zhejiang University, School of Medicine, Hangzhou, China
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Mònica Recasens
Mònica Recasens
Hospital Universitari de Girona, Gerencia Territorial Girona, Institut Català de la Salut, Girona, Spain
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Luis Robles Díaz
Luis Robles Díaz
Unidad de Tumores Digestivos, Servicio de Oncología Médica, Hospital Universitario 12 de Octubre, Madrid, Spain
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Tada Kunavisarut
Tada Kunavisarut
Division of Endocrinology and metabolism, Siriraj Hospital, Mahidol University, Bangkok, Thailand
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Taweesak Wannachalee
Taweesak Wannachalee
Division of Endocrinology and metabolism, Siriraj Hospital, Mahidol University, Bangkok, Thailand
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Sirinart Sirinvaravong
Sirinart Sirinvaravong
Division of Endocrinology and metabolism, Siriraj Hospital, Mahidol University, Bangkok, Thailand
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Eric Jonasch
Eric Jonasch
Department of Genitourinary Medical Oncology, Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA
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Simona Grozinsky-Glasberg
Simona Grozinsky-Glasberg
Neuroendocrine Tumor Division, Endocrinology & Metabolism Service, Department of Medicine, Hadassah-Hebrew University Medical Center, Jerusalem, Israel
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Merav Fraenkel
Merav Fraenkel
Neuroendocrine Tumor Division, Endocrinology & Metabolism Service, Department of Medicine, Hadassah-Hebrew University Medical Center, Jerusalem, Israel
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Dmitry Beltsevich
Dmitry Beltsevich
Department of Surgery, Endocrinology Research Center, Moscow, Russia
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Viacheslav I Egorov
Viacheslav I Egorov
Department of Surgery, Bakhrushin Brothers Moscow City Hospital, Moscow, Russia
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Dirk Bausch
Dirk Bausch
Department of Surgery, University of Luebeck, Luebeck, Germany
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Matthias Schott
Matthias Schott
Department of Endocrinology, Heinrich-Heine-University, Düsseldorf, Germany
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Nikolaus Tiling
Nikolaus Tiling
Interdisciplinary Center of Metabolism: Endocrinology, Diabetes and Metabolism, Charité-University Medicine Berlin, Campus Virchow-Klinikum, Berlin, Germany
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Gianmaria Pennelli
Gianmaria Pennelli
Department of Medicine (DIMED), Surgical Pathology Unit, University of Padua, Padua, Italy
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Stefan Zschiedrich
Stefan Zschiedrich
Department of Medicine IV, Faculty of Medicine, Albert-Ludwigs-University, Freiburg, Germany
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Roland Därr
Roland Därr
Department of Medicine IV, Faculty of Medicine, Albert-Ludwigs-University, Freiburg, Germany
Department of Cardiology and Angiology I, Heart Center Freiburg University, Faculty of Medicine, University of Freiburg, Freiburg, Germany
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Department of Cardiology and Angiology I, Heart Center Freiburg University, Faculty of Medicine, University of Freiburg, Freiburg, Germany
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Juri Ruf
Juri Ruf
Department of Nuclear Medicine, Faculty of Medicine, Albert-Ludwigs-University, Freiburg, Germany
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Timm Denecke
Timm Denecke
Department of Radiology, Campus Virchow-Klinikum, Charité – Universitätsmedizin Berlin, Berlin, Germany
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Karl-Heinrich Link
Karl-Heinrich Link
Department of Surgery, Asklepios-Paulinen Klinik, Wiesbaden, Germany
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Stefania Zovato
Stefania Zovato
Familial Cancer Clinic and Oncoendocrinology, Veneto Institute of Oncology IOV- IRCCS, Padua, Italy
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Ernst von Dobschuetz
Ernst von Dobschuetz
Section of Endocrine Surgery, Reinbek Hospital, Academic Teaching Hospital University of Hamburg, Reinbek, Germany
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Svetlana Yaremchuk
Svetlana Yaremchuk
Institute of Endocrinology and Metabolism, NAMS of Ukraine, Kiev, Ukraine
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Holger Amthauer
Holger Amthauer
Department of Clinical Nuclear Medicine, Charité – Universitätsmedizin Berlin, Berlin, Germany
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Özer Makay
Özer Makay
Department of General Surgery, Division of Endocrine Surgery, Izmir, Turkey
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Attila Patocs
Attila Patocs
2nd Department of Medicine and Molecular Medicine Research Group, Hungarian Academy of Sciences, Semmelweis-University, Budapest, Hungary
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Martin K Walz
Martin K Walz
Department of Surgery, Huyssens Foundation Clinics, Essen, Germany
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Tobias B Huber
Tobias B Huber
3rd Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany
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Jochen Seufert
Jochen Seufert
Department of Medicine II, Faculty of Medicine, Medical Center – University of Freiburg, University of Freiburg, Freiburg, Germany
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Per Hellman
Per Hellman
Department of Surgical Sciences, Uppsala University, University Hospital, Uppsala, Sweden
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Raymond H Kim
Raymond H Kim
Department of Medicine, University of Toronto, University Healthy Network & Mount Sinai Hospital, The Fred A Litwin Family Center in Genetic Medicine, Toronto, Ontario, Canada
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Ekaterina Kuchinskaya
Ekaterina Kuchinskaya
Department of Clinical Genetics and Department of Clinical and Experimental Medicine, Linköping University, Linköping, Sweden
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Francesca Schiavi
Francesca Schiavi
Familial Cancer Clinic and Oncoendocrinology, Veneto Institute of Oncology IOV- IRCCS, Padua, Italy
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Angelica Malinoc
Angelica Malinoc
Department of Medicine IV, Faculty of Medicine, Albert-Ludwigs-University, Freiburg, Germany
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Nicole Reisch
Nicole Reisch
Department of Endocrinology, Ludwigs-Maximilians-University of Munich, Munich, Germany
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Barbara Jarzab
Barbara Jarzab
Department of Endocrine Oncology and Nuclear Medicine, Center of Oncology, MSC Memorial Institute, Gliwice, Poland
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Marta Barontini
Marta Barontini
Centro de Investigaciones Endocrinológicas “Dr Cesar Bergada” (CEDIE), Hospital de Niños Ricardo Gutiérrez, CABA, Buenos Aires, Argentina
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Andrzej Januszewicz
Andrzej Januszewicz
Department of Hypertension, Institute of Cardiology, Warsaw, Poland
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Nalini Shah
Nalini Shah
Department of Endocrinology, KEM Hospital, Mumbai, India
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William F Young Jr
William F Young Jr
Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic, Rochester, USA
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Giuseppe Opocher
Giuseppe Opocher
Scientific Direction, Veneto Institute of Oncology IOV-IRCCS, Padua, Italy
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Charis Eng
Charis Eng
Genomic Medicine Institute, Lerner Research Institute and Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio, USA
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Hartmut P H Neumann
Hartmut P H Neumann
Section for Preventive Medicine, Faculty of Medicine, Albert-Ludwigs-University, Freiburg, Germany
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Birke Bausch
Birke Bausch
Department of Medicine II, Faculty of Medicine, Medical Center – University of Freiburg, University of Freiburg, Freiburg, Germany
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). Pancreatic neuroendocrine tumors (PanNETs) originate from the islets of the pancreas and may be hormonally active or inactive. PanNETs occur mainly as sporadic tumors, but 9% are also components of three hereditary syndromes, multiple endocrine neoplasia type
Mojun Zhu
Mojun Zhu
Department of Oncology, Mayo Clinic, Rochester, Minnesota, USA
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Karl R Sorenson
Karl R Sorenson
Department of Oncology, Mayo Clinic, Rochester, Minnesota, USA
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Rebecca Liu
Rebecca Liu
Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA
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Bonnie E Gould Rothberg
Bonnie E Gould Rothberg
Smilow Cancer Hospital, Yale-New Haven Health System, New Haven, Connecticut, USA
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Thorvardur R Halfdanarson
Thorvardur R Halfdanarson
Department of Oncology, Mayo Clinic, Rochester, Minnesota, USA
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Introduction Pancreatic neuroendocrine tumors (PNETs) are a group of heterogeneous malignancies with diverse pathological findings and clinical behaviors. With an annual incidence that is less than 1 per 100,000 ( Halfdanarson et al. 2008
Thomas Cuny
Thomas Cuny
Division Endocrinology, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands
Aix-Marseille Université, Institut National de la Santé et de la Recherche Médicale (INSERM), U1251, Marseille Medical Genetics (MMG), Marseille, France
Department of Endocrinology, Assistance Publique – Hôpitaux de Marseille (AP-HM), Hôpital de la Conception, Centre de Référence des Maladies Rares Hypophysaires HYPO, Marseille, France
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Aix-Marseille Université, Institut National de la Santé et de la Recherche Médicale (INSERM), U1251, Marseille Medical Genetics (MMG), Marseille, France
Department of Endocrinology, Assistance Publique – Hôpitaux de Marseille (AP-HM), Hôpital de la Conception, Centre de Référence des Maladies Rares Hypophysaires HYPO, Marseille, France
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Wouter de Herder
Wouter de Herder
Division Endocrinology, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands
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Anne Barlier
Anne Barlier
Aix-Marseille Université, Institut National de la Santé et de la Recherche Médicale (INSERM), U1251, Marseille Medical Genetics (MMG), Marseille, France
Department of Endocrinology, Assistance Publique – Hôpitaux de Marseille (AP-HM), Hôpital de la Conception, Centre de Référence des Maladies Rares Hypophysaires HYPO, Marseille, France
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Department of Endocrinology, Assistance Publique – Hôpitaux de Marseille (AP-HM), Hôpital de la Conception, Centre de Référence des Maladies Rares Hypophysaires HYPO, Marseille, France
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Leo J Hofland
Leo J Hofland
Division Endocrinology, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands
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Introduction Human gastroenteropancreatic neuroendocrine tumors (GEP-NETs) represent a heterogeneous group of tumors emerging from cells producing glycopeptides and biogenic amines ( Klöppel 2011 ). They account for approximately 0.5% of all
Aristides Lytras
Aristides Lytras
Division of Endocrinology and Metabolism, Hippocrateion General Hospital, Vas. Sofias 108, GR 115-27 Athens, Greece
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George Tolis
George Tolis
Division of Endocrinology and Metabolism, Hippocrateion General Hospital, Vas. Sofias 108, GR 115-27 Athens, Greece
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Introduction Multiple neuroendocrine tumor syndromes may appear in a sporadic mode. The McCune–Albright syndrome (MAS; OMIM #174 800), a sporadic disease, representing a mosaic case of GNAS gene mutation leading to stimulatory G-protein α subunit (G
