Introduction Pheochromocytomas (PCCs) are neuroendocrine tumors that originate from chromaffin cells of the adrenal medulla or autonomic nervous system, where they are termed paragangliomas (PGLs). The majority of the morbidity associated with
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Samuel M O’Toole, David S Watson, Tatiana V Novoselova, Lisa E L Romano, Peter J King, Teisha Y Bradshaw, Clare L Thompson, Martin M Knight, Tyson V Sharp, Michael R Barnes, Umasuthan Srirangalingam, William M Drake, and J Paul Chapple
Marta Araujo-Castro, Rogelio Garcia Centeno, María-Carmen López-García, Cristina Lamas, Cristina Álvarez-Escolá, María Calatayud Gutiérrez, Concepción Blanco-Carrera, Paz de Miguel Novoa, Nuria Valdés, Paola Gracia Gimeno, Mariana Tomé Fernández-Ladreda, César Mínguez Ojeda, Juan Carlos Percovich Hualpa, Mireia Mora, Óscar Vidal, Ana Serrano Romero, Felicia Alexandra Hanzu, and Victoria Gómez Dos Santos
Introduction Pheochromocytomas are rare neuroendocrine tumours that produce catecholamines ( Lenders et al. 2014 ). Anaesthetic induction and surgical manipulation of the tumour can precipitate the release of an excessive amount of
Birke Bausch, Ulrich Wellner, Dirk Bausch, Francesca Schiavi, Marta Barontini, Gabriela Sanso, Martin K Walz, Mariola Peczkowska, Georges Weryha, Patrizia Dall'Igna, Giovanni Cecchetto, Gianni Bisogno, Lars C Moeller, Detlef Bockenhauer, Attila Patocs, Karoly Rácz, Dmitry Zabolotnyi, Svetlana Yaremchuk, Iveta Dzivite-Krisane, Frederic Castinetti, David Taieb, Angelica Malinoc, Ernst von Dobschuetz, Jochen Roessler, Kurt W Schmid, Giuseppe Opocher, Charis Eng, and Hartmut P H Neumann
Introduction Pheochromocytomas and paragangliomas are tumors of the overall paraganglial system, mainly the adrenal glands, the retroperitoneum, the pelvis, the thorax, and the skullbase and neck regions ( Neumann 2008 ). Such paraganglial tumors
Jacques Amar, Jeremy Brunel, Catherine Cardot Bauters, Virginie Jacques, Clément Delmas, Marie-Françoise Odou, and Frédérique Savagner
Introduction Pheochromocytoma–paraganglioma (PPGL) are rare tumors ( Berends et al. 2018 ) that produce and store catecholamines. The release of excessive amounts of catecholamines can lead to life-threatening cardiovascular complications
Douglas Wiseman, James D McDonald, Dhaval Patel, Electron Kebebew, Karel Pacak, and Naris Nilubol
Introduction Pheochromocytomas and paragangliomas (PPGLs) are rare, catecholamine-secreting tumors arising from the chromaffin cells of the adrenal medulla and extra-adrenal neural crest tissues, which run from the skull base to the pelvis
Trisha Dwight, Aidan Flynn, Kaushalya Amarasinghe, Diana E Benn, Richard Lupat, Jason Li, Daniel L Cameron, Annette Hogg, Shiva Balachander, Ida L M Candiloro, Stephen Q Wong, Bruce G Robinson, Anthony T Papenfuss, Anthony J Gill, Alexander Dobrovic, Rodney J Hicks, Roderick J Clifton-Bligh, and Richard W Tothill
Introduction Pheochromocytomas (PC) and paragangliomas (PGLs) are neuroendocrine tumors derived from neural crest cells of the sympathetic and parasympathetic nervous system – PCs arising in the adrenal medulla and PGLs in paraganglia outside
Atanaska Elenkova, Rabhat Shabani, Elena Kinova, Vladimir Vasilev, Assen Goudev, and Sabina Zacharieva
Introduction Cardiovascular disturbances are the major clinical manifestations of pheochromocytoma. Arterial hypertension is the leading symptom in approximately 90% of all patients, usually with a paroxysmal course, severe, malignant or
Camilo Jimenez, Bennett B Chin, Richard B Noto, Joseph S Dillon, Lilja Solnes, Nancy Stambler, Vincent A DiPippo, and Daniel A Pryma
Introduction Pheochromocytomas and paragangliomas (PPGLs) are rare neuroendocrine tumors derived from chromaffin cells of the adrenal medulla and paraganglia, respectively ( Jimenez 2018 ). Each year, approximately 500–1600 new cases of PPGLs
Marta Araujo-Castro, César Mínguez Ojeda, Rogelio García Centeno, María-Carmen López-García, Cristina Lamas, Felicia Alexandra Hanzu, Mireia Mora, María del Castillo Tous, Pablo Rodríguez de Vera Gómez, Paola Parra Ramírez, Cristina Alvarez-Escola, Concepción Blanco Carrera, Rebeca Barahona San Millán, Mónica Recasens, Nuria Valdés, Paola Gracia Gimeno, Paz de Miguel Novoa, Almudena Vicente, Laura Manjón, Iñigo García Sanz, Theodora Michalopoulou, and María Calatayud
Introduction Pheochromocytomas and sympathetic paragangliomas (together PPGLs) are rare neuroendocrine tumors that arise from chromaffin tissue and produce catecholamines ( Lenders et al. 2014 ). Patients with PPGLs most commonly present
Pauline Croisé, Sébastien Houy, Mathieu Gand, Joël Lanoix, Valérie Calco, Petra Tóth, Laurent Brunaud, Sandra Lomazzi, Eustache Paramithiotis, Daniel Chelsky, Stéphane Ory, and Stéphane Gasman
. Results Protein expression and activity of RhoA, Rac1 and Cdc42 in human pheochromocytomas The expression level and the activity of Rho GTPases have never been explored in human PCC. To do so, we have used the ELISA-based assay (G-LISA; Cytoskeleton