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Maria Eugenia Sabatino
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Juan Pablo Petiti
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Liliana del Valle Sosa
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Pablo Anibal Pérez
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Silvina Gutiérrez
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Carolina Leimgruber
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Alexandra Latini Facultad de Ciencias Médicas, Laboratorio de Bioenergética y Estrés Oxidativo, Instituto de Investigaciones en Ciencias de la Salud (INICSA–CONICET), Centro de Microscopía Electrónica, Universidad Nacional de Córdoba, Av. Enrique Barros y Enfermera Gordillo, Ciudad Universitaria, 5000 Córdoba, Argentina

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Alicia Inés Torres
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Ana Lucía De Paul
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). Nevertheless, several alterations in cell growth can lead to pituitary hyperplasia and high levels of hormone production, frequently related to adenoma formation ( Asa & Ezzat 2009 ). Pituitary adenomas represent 25% of intracranial tumors, with their

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-14-0333
Volume/Issue:
Volume 22: Issue 3
Free access
Ines Donangelo Pituitary Center, Regenerative Medicine Institute, Cedars‐Sinai Medical Center,

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Song-Guang Ren Pituitary Center, Regenerative Medicine Institute, Cedars‐Sinai Medical Center,

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Tamar Eigler Pituitary Center, Regenerative Medicine Institute, Cedars‐Sinai Medical Center,

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Clive Svendsen Pituitary Center, Regenerative Medicine Institute, Cedars‐Sinai Medical Center,

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Shlomo Melmed Pituitary Center, Regenerative Medicine Institute, Cedars‐Sinai Medical Center,

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Introduction Pituitary tumors are invariably benign neoplasms identified in ∼25% of unselected autopsy specimens, and may cause considerable morbidity due to excess hormone secretion and/or compression of surrounding brain structures ( Melmed 2003

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-13-0229
Volume/Issue:
Volume 21: Issue 2
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Kari Hemminki
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Asta Försti
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Jianguang Ji
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Introduction Pituitary adenomas are indolent tumors, which account for 10–15% of all diagnosed intracranial neoplasms ( Asa & Ezzat 2002 , DeLellis et al. 2004 ). Small adenomas may occur in up to 15% of pituitary glands examined

Article Type:
Research Article
DOI:
https://doi.org/10.1677/ERC-06-0008
Volume/Issue:
Volume 14: Issue 1
Free access
Mirela Diana Ilie Inserm U1052, CNRS UMR5286, Claude Bernard Lyon 1 University, Cancer Research Center of Lyon, Lyon, France
Endocrinology Department, ‘C.I. Parhon’ National Institute of Endocrinology, Bucharest, Romania

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Alexandre Vasiljevic Inserm U1052, CNRS UMR5286, Claude Bernard Lyon 1 University, Cancer Research Center of Lyon, Lyon, France
Pathology Department, Reference Center for Rare Pituitary Diseases HYPO, ‘Groupement Hospitalier Est’ Hospices Civils de Lyon, Bron, France

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Emmanuel Jouanneau Inserm U1052, CNRS UMR5286, Claude Bernard Lyon 1 University, Cancer Research Center of Lyon, Lyon, France
Neurosurgery Department, Reference Center for Rare Pituitary Diseases HYPO, ‘Groupement Hospitalier Est’ Hospices Civils de Lyon, Bron, France

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Gérald Raverot Inserm U1052, CNRS UMR5286, Claude Bernard Lyon 1 University, Cancer Research Center of Lyon, Lyon, France
Endocrinology Department, Reference Center for Rare Pituitary Diseases HYPO, ‘Groupement Hospitalier Est’ Hospices Civils de Lyon, Bron, France

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Introduction Anterior pituitary tumors are usually benign neoplasms that derive from the endocrine cells of the anterior pituitary gland. However, a small percentage of them have an aggressive behavior, showing resistance and/or multiple

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-22-0037
Volume/Issue:
Volume 29: Issue 7
Restricted access
Charlotte Nys Laboratory of Tissue Plasticity in Health and Disease, Cluster of Stem Cell and Developmental Biology, Department of Development and Regeneration, KU Leuven (University of Leuven), Leuven, Belgium

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Yu-Lun Lee Laboratory of Tissue Plasticity in Health and Disease, Cluster of Stem Cell and Developmental Biology, Department of Development and Regeneration, KU Leuven (University of Leuven), Leuven, Belgium

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Heleen Roose Laboratory of Tissue Plasticity in Health and Disease, Cluster of Stem Cell and Developmental Biology, Department of Development and Regeneration, KU Leuven (University of Leuven), Leuven, Belgium

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Freya Mertens Laboratory of Tissue Plasticity in Health and Disease, Cluster of Stem Cell and Developmental Biology, Department of Development and Regeneration, KU Leuven (University of Leuven), Leuven, Belgium
Department of Imaging and Pathology, UZ Leuven (University Hospitals Leuven), Leuven, Belgium

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Ellen De Pauw Laboratory of Tissue Plasticity in Health and Disease, Cluster of Stem Cell and Developmental Biology, Department of Development and Regeneration, KU Leuven (University of Leuven), Leuven, Belgium

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Hiroto Kobayashi Laboratory of Tissue Plasticity in Health and Disease, Cluster of Stem Cell and Developmental Biology, Department of Development and Regeneration, KU Leuven (University of Leuven), Leuven, Belgium
Department of Anatomy and Structural Science, Yamagata University Faculty of Medicine, Yamagata, Japan

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Raf Sciot Department of Imaging and Pathology, UZ Leuven (University Hospitals Leuven), Leuven, Belgium

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Marie Bex Department of Endocrinology, UZ Leuven (University Hospitals Leuven), Leuven, Belgium

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Georges Versyck Department of Neurosurgery, UZ Leuven (University Hospitals Leuven), Leuven, Belgium

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Steven De Vleeschouwer Department of Neurosurgery, UZ Leuven (University Hospitals Leuven), Leuven, Belgium

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Johannes Van Loon Department of Neurosurgery, UZ Leuven (University Hospitals Leuven), Leuven, Belgium

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Emma Laporte Laboratory of Tissue Plasticity in Health and Disease, Cluster of Stem Cell and Developmental Biology, Department of Development and Regeneration, KU Leuven (University of Leuven), Leuven, Belgium

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Hugo Vankelecom Laboratory of Tissue Plasticity in Health and Disease, Cluster of Stem Cell and Developmental Biology, Department of Development and Regeneration, KU Leuven (University of Leuven), Leuven, Belgium

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prevalent, being detected in 15–25% of the general population, with serious clinical symptoms in 0.1% ( Ezzat et al. 2004 , Daly et al. 2009 , Mete & Lopes 2017 , Melmed 2020 ). Although pituitary tumors mainly represent benign and slow

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-21-0374
Volume/Issue:
Volume 29: Issue 7
Restricted access
Freya Mertens Department of Development and Regeneration, Department of Hand Surgery, Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Center of the 2nd Affiliated Hospital, Department of Imaging and Pathology, CITNOBA (National Research Council of Argentina), Laboratory of Pituitary Regulation, Unit Head and Neck Oncology, Research Group Experimental Oto‐Rhino‐Laryngology, Unit Clinical and Experimental Endocrinology, Research Group Experimental Neurosurgery and Neuroanatomy, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, KU Leuven (University of Leuven), Campus Gasthuisberg O&N4, Herestraat 49, B-3000 Leuven, Belgium

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Lies Gremeaux Department of Development and Regeneration, Department of Hand Surgery, Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Center of the 2nd Affiliated Hospital, Department of Imaging and Pathology, CITNOBA (National Research Council of Argentina), Laboratory of Pituitary Regulation, Unit Head and Neck Oncology, Research Group Experimental Oto‐Rhino‐Laryngology, Unit Clinical and Experimental Endocrinology, Research Group Experimental Neurosurgery and Neuroanatomy, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, KU Leuven (University of Leuven), Campus Gasthuisberg O&N4, Herestraat 49, B-3000 Leuven, Belgium

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Jianghai Chen Department of Development and Regeneration, Department of Hand Surgery, Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Center of the 2nd Affiliated Hospital, Department of Imaging and Pathology, CITNOBA (National Research Council of Argentina), Laboratory of Pituitary Regulation, Unit Head and Neck Oncology, Research Group Experimental Oto‐Rhino‐Laryngology, Unit Clinical and Experimental Endocrinology, Research Group Experimental Neurosurgery and Neuroanatomy, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, KU Leuven (University of Leuven), Campus Gasthuisberg O&N4, Herestraat 49, B-3000 Leuven, Belgium
Department of Development and Regeneration, Department of Hand Surgery, Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Center of the 2nd Affiliated Hospital, Department of Imaging and Pathology, CITNOBA (National Research Council of Argentina), Laboratory of Pituitary Regulation, Unit Head and Neck Oncology, Research Group Experimental Oto‐Rhino‐Laryngology, Unit Clinical and Experimental Endocrinology, Research Group Experimental Neurosurgery and Neuroanatomy, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, KU Leuven (University of Leuven), Campus Gasthuisberg O&N4, Herestraat 49, B-3000 Leuven, Belgium

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Qiuli Fu Department of Development and Regeneration, Department of Hand Surgery, Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Center of the 2nd Affiliated Hospital, Department of Imaging and Pathology, CITNOBA (National Research Council of Argentina), Laboratory of Pituitary Regulation, Unit Head and Neck Oncology, Research Group Experimental Oto‐Rhino‐Laryngology, Unit Clinical and Experimental Endocrinology, Research Group Experimental Neurosurgery and Neuroanatomy, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, KU Leuven (University of Leuven), Campus Gasthuisberg O&N4, Herestraat 49, B-3000 Leuven, Belgium
Department of Development and Regeneration, Department of Hand Surgery, Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Center of the 2nd Affiliated Hospital, Department of Imaging and Pathology, CITNOBA (National Research Council of Argentina), Laboratory of Pituitary Regulation, Unit Head and Neck Oncology, Research Group Experimental Oto‐Rhino‐Laryngology, Unit Clinical and Experimental Endocrinology, Research Group Experimental Neurosurgery and Neuroanatomy, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, KU Leuven (University of Leuven), Campus Gasthuisberg O&N4, Herestraat 49, B-3000 Leuven, Belgium
Department of Development and Regeneration, Department of Hand Surgery, Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Center of the 2nd Affiliated Hospital, Department of Imaging and Pathology, CITNOBA (National Research Council of Argentina), Laboratory of Pituitary Regulation, Unit Head and Neck Oncology, Research Group Experimental Oto‐Rhino‐Laryngology, Unit Clinical and Experimental Endocrinology, Research Group Experimental Neurosurgery and Neuroanatomy, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, KU Leuven (University of Leuven), Campus Gasthuisberg O&N4, Herestraat 49, B-3000 Leuven, Belgium

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Christophe Willems Department of Development and Regeneration, Department of Hand Surgery, Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Center of the 2nd Affiliated Hospital, Department of Imaging and Pathology, CITNOBA (National Research Council of Argentina), Laboratory of Pituitary Regulation, Unit Head and Neck Oncology, Research Group Experimental Oto‐Rhino‐Laryngology, Unit Clinical and Experimental Endocrinology, Research Group Experimental Neurosurgery and Neuroanatomy, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, KU Leuven (University of Leuven), Campus Gasthuisberg O&N4, Herestraat 49, B-3000 Leuven, Belgium

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Heleen Roose Department of Development and Regeneration, Department of Hand Surgery, Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Center of the 2nd Affiliated Hospital, Department of Imaging and Pathology, CITNOBA (National Research Council of Argentina), Laboratory of Pituitary Regulation, Unit Head and Neck Oncology, Research Group Experimental Oto‐Rhino‐Laryngology, Unit Clinical and Experimental Endocrinology, Research Group Experimental Neurosurgery and Neuroanatomy, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, KU Leuven (University of Leuven), Campus Gasthuisberg O&N4, Herestraat 49, B-3000 Leuven, Belgium

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Olivier Govaere Department of Development and Regeneration, Department of Hand Surgery, Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Center of the 2nd Affiliated Hospital, Department of Imaging and Pathology, CITNOBA (National Research Council of Argentina), Laboratory of Pituitary Regulation, Unit Head and Neck Oncology, Research Group Experimental Oto‐Rhino‐Laryngology, Unit Clinical and Experimental Endocrinology, Research Group Experimental Neurosurgery and Neuroanatomy, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, KU Leuven (University of Leuven), Campus Gasthuisberg O&N4, Herestraat 49, B-3000 Leuven, Belgium

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Tania Roskams Department of Development and Regeneration, Department of Hand Surgery, Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Center of the 2nd Affiliated Hospital, Department of Imaging and Pathology, CITNOBA (National Research Council of Argentina), Laboratory of Pituitary Regulation, Unit Head and Neck Oncology, Research Group Experimental Oto‐Rhino‐Laryngology, Unit Clinical and Experimental Endocrinology, Research Group Experimental Neurosurgery and Neuroanatomy, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, KU Leuven (University of Leuven), Campus Gasthuisberg O&N4, Herestraat 49, B-3000 Leuven, Belgium

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Carolina Cristina Department of Development and Regeneration, Department of Hand Surgery, Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Center of the 2nd Affiliated Hospital, Department of Imaging and Pathology, CITNOBA (National Research Council of Argentina), Laboratory of Pituitary Regulation, Unit Head and Neck Oncology, Research Group Experimental Oto‐Rhino‐Laryngology, Unit Clinical and Experimental Endocrinology, Research Group Experimental Neurosurgery and Neuroanatomy, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, KU Leuven (University of Leuven), Campus Gasthuisberg O&N4, Herestraat 49, B-3000 Leuven, Belgium

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Damasia Becú-Villalobos Department of Development and Regeneration, Department of Hand Surgery, Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Center of the 2nd Affiliated Hospital, Department of Imaging and Pathology, CITNOBA (National Research Council of Argentina), Laboratory of Pituitary Regulation, Unit Head and Neck Oncology, Research Group Experimental Oto‐Rhino‐Laryngology, Unit Clinical and Experimental Endocrinology, Research Group Experimental Neurosurgery and Neuroanatomy, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, KU Leuven (University of Leuven), Campus Gasthuisberg O&N4, Herestraat 49, B-3000 Leuven, Belgium

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Mark Jorissen Department of Development and Regeneration, Department of Hand Surgery, Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Center of the 2nd Affiliated Hospital, Department of Imaging and Pathology, CITNOBA (National Research Council of Argentina), Laboratory of Pituitary Regulation, Unit Head and Neck Oncology, Research Group Experimental Oto‐Rhino‐Laryngology, Unit Clinical and Experimental Endocrinology, Research Group Experimental Neurosurgery and Neuroanatomy, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, KU Leuven (University of Leuven), Campus Gasthuisberg O&N4, Herestraat 49, B-3000 Leuven, Belgium

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Vincent Vander Poorten Department of Development and Regeneration, Department of Hand Surgery, Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Center of the 2nd Affiliated Hospital, Department of Imaging and Pathology, CITNOBA (National Research Council of Argentina), Laboratory of Pituitary Regulation, Unit Head and Neck Oncology, Research Group Experimental Oto‐Rhino‐Laryngology, Unit Clinical and Experimental Endocrinology, Research Group Experimental Neurosurgery and Neuroanatomy, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, KU Leuven (University of Leuven), Campus Gasthuisberg O&N4, Herestraat 49, B-3000 Leuven, Belgium

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Marie Bex Department of Development and Regeneration, Department of Hand Surgery, Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Center of the 2nd Affiliated Hospital, Department of Imaging and Pathology, CITNOBA (National Research Council of Argentina), Laboratory of Pituitary Regulation, Unit Head and Neck Oncology, Research Group Experimental Oto‐Rhino‐Laryngology, Unit Clinical and Experimental Endocrinology, Research Group Experimental Neurosurgery and Neuroanatomy, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, KU Leuven (University of Leuven), Campus Gasthuisberg O&N4, Herestraat 49, B-3000 Leuven, Belgium

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Johannes van Loon Department of Development and Regeneration, Department of Hand Surgery, Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Center of the 2nd Affiliated Hospital, Department of Imaging and Pathology, CITNOBA (National Research Council of Argentina), Laboratory of Pituitary Regulation, Unit Head and Neck Oncology, Research Group Experimental Oto‐Rhino‐Laryngology, Unit Clinical and Experimental Endocrinology, Research Group Experimental Neurosurgery and Neuroanatomy, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, KU Leuven (University of Leuven), Campus Gasthuisberg O&N4, Herestraat 49, B-3000 Leuven, Belgium

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Hugo Vankelecom Department of Development and Regeneration, Department of Hand Surgery, Zhejiang Provincial Key Laboratory of Ophthalmology, Eye Center of the 2nd Affiliated Hospital, Department of Imaging and Pathology, CITNOBA (National Research Council of Argentina), Laboratory of Pituitary Regulation, Unit Head and Neck Oncology, Research Group Experimental Oto‐Rhino‐Laryngology, Unit Clinical and Experimental Endocrinology, Research Group Experimental Neurosurgery and Neuroanatomy, Cluster Stem Cell Biology and Embryology, Research Unit of Stem Cell Research, KU Leuven (University of Leuven), Campus Gasthuisberg O&N4, Herestraat 49, B-3000 Leuven, Belgium

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Introduction Pituitary tumors are generally benign adenomas. Radiology and autopsy, being performed for reasons other than pituitary-related medical ones, show a high prevalence of 10–15% in the overall population, although most of these lesions are

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-14-0546
Volume/Issue:
Volume 22: Issue 4
Free access
S L Asa Department of Pathology and Endocrine Oncology Site Group, Princess Margaret Cancer Centre, University Health Network, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada

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O Casar-Borota Department of Pathology, Uppsala University Hospital, Uppsala, Sweden

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P Chanson Service of Endocrinology and Reproductive Diseases, Bicêtre Hospital, Paris, France

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E Delgrange Department of Medicine, University of Louvain, Mont-sur-Meuse, Belgium

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P Earls Department of Anatomical Pathology, St Vincent’s Hospital, Sydney, Australia

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S Ezzat Department of Medicine and Endocrine Oncology Site Group, Princess Margaret Cancer Centre, University Health Network and University of Toronto, Toronto, Ontario, Canada

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A Grossman Department of Endocrinology, University of Oxford, Oxford, UK

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H Ikeda Research Institute for Pituitary Disease, Southern Tohoku General Hospital, Fukushima, Japan

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N Inoshita Department of Pathology, Toranomon Hospital, Tokyo, Japan

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N Karavitaki Department of Endocrinology, Queen Elizabeth Hospital, University of Birmingham, Birmingham, UK

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M Korbonits Division of Endocrinology, Queen Mary Hospital, Barts and the London School of Medicine, London, UK

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E R Laws Jr Department of Neurosurgery, Harvard Medical School, Brigham & Women’s Hospital, Boston, Massachusetts, USA

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M B Lopes Departments of Pathology and Neurological Surgery, University of Virginia, Charlottesville, Virginia, USA

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N Maartens Department of Neurosurgery, Royal Melbourne Hospital, The University of Melbourne, Melbourne, Australia

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I E McCutcheon Department of Neurosurgery, UT MD Anderson Cancer Center, Houston, Texas, USA

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O Mete Department of Pathology and Endocrine Oncology Site Group, Princess Margaret Cancer Centre, University Health Network, Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada

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H Nishioka Department of Neurosurgery, Toranomon Hospital, Tokyo, Japan

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G Raverot Department of Endocrinology, Groupement Hospitalier EST, Hospices Civils de Lyon, University of Lyon, Lyon, France

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F Roncaroli Department of Neuropathology, Imperial College, London, UK

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W Saeger Institute of Neuropathology of the University of Hamburg, Hamburg, Germany

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L V Syro Department of Neurosurgery, Hospital Pablo Tobon Uribe, Medellin, Colombia

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A Vasiljevic Department of Pathology, Groupement Hospitalier EST, Hospices Civils de Lyon, University of Lyon, Lyon, France

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C Villa Department of Pathology, Hôpital Foch, Suresnes, France

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A Wierinckx INSERM U1052, Cancer Research Center of Lyon, University of Lyon, Lyon, France

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J Trouillas Faculty of Medicine Lyon-Est, University of Lyon, Lyon, France

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and the attendees of 14th Meeting of the International Pituitary Pathology Club, Annecy, France, November 2016
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Since the early work of Minkowski, who attributed acromegaly to a pituitary tumor ( Minkowski 1887 ), neoplasms composed of pituitary adenohypophysial cells have been recognized as the cause of significant illness. However, Harvey Cushing

Article Type:
Article Commentary
DOI:
https://doi.org/10.1530/ERC-17-0004
Volume/Issue:
Volume 24: Issue 4
Free access
G Mantovani Endocrinology Unit, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy

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D Treppiedi Endocrinology Unit, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy

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E Giardino Endocrinology Unit, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy

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R Catalano Endocrinology Unit, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy
PhD Program in Endocrinological Sciences, Sapienza University of Rome, Rome, Italy

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F Mangili Endocrinology Unit, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy

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P Vercesi Endocrinology Unit, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy

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M Arosio Endocrinology Unit, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy

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A Spada Endocrinology Unit, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy

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E Peverelli Endocrinology Unit, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy

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Introduction Pituitary tumors, accounting for 16.2% of all primary brain and other central nervous system tumors ( Ostrom et al. 2017 ), are classified based on their secretory activity in non-functioning pituitary tumors (NFPTs) or hormone

Article Type:
Review Article
DOI:
https://doi.org/10.1530/ERC-18-0442
Volume/Issue:
Volume 26: Issue 2
Free access
Yong Lin
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Xiaofei Jiang
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Ye Shen Department of Laboratory Medicine, Institute of Endocrinology and Diabetologia, Division of Endocrinology and Metabolism, Huashan Hospital, Shanghai Medical College, Fudan University, 12 Central Urumqi Road, Shanghai 200040, People's Republic of China

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Min Li
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Huili Ma
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Mingzhao Xing Department of Laboratory Medicine, Institute of Endocrinology and Diabetologia, Division of Endocrinology and Metabolism, Huashan Hospital, Shanghai Medical College, Fudan University, 12 Central Urumqi Road, Shanghai 200040, People's Republic of China

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Yuan Lu
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et al . 2002 , Byun et al . 2003 , Samuels et al . 2004 , Wu et al . 2005 , Kozaki et al . 2006 ). Pituitary tumors are common endocrine neoplastic diseases. Multiple tumor-promoting factors or signaling pathways are known to be involved

Article Type:
Research Article
DOI:
https://doi.org/10.1677/ERC-08-0167
Volume/Issue:
Volume 16: Issue 1
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Cuiqi Zhou Pathology, Departments of

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Yunguang Tong Pathology, Departments of

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Kolja Wawrowsky Pathology, Departments of

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Serguei Bannykh Pathology, Departments of

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Ines Donangelo Pathology, Departments of

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Shlomo Melmed Pathology, Departments of

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Introduction Pituitary tumor transforming gene (PTTG1), the index mammalian securin, was isolated from rat pituitary tumor cells ( Pei & Melmed 1997 ), and the human homolog (hPTTG1) was identified as a proto-oncogene ( Zhang et al . 1999 b

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DOI:
https://doi.org/10.1677/ERC-08-0060
Volume/Issue:
Volume 15: Issue 3
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