the incidence of peptic ulcer disease ( Hirschowitz et al . 2005 ). It is without question that before all these contemporary options were available, patients with a hypersecreting NET had a worse prognosis, due to the complications of hormone
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Wouter T Zandee, Kimberly Kamp, Roxanne C van Adrichem, Richard A Feelders, and Wouter W de Herder
Kristina Warton, Kate L Mahon, and Goli Samimi
Methylated circulating DNA in cancer prognosis and monitoring Genomics is anticipated to bring major improvements in the treatment of cancer patients. The capacity to quickly and relatively inexpensively sequence tumor DNA on a genome-wide scale
Mojun Zhu, Karl R Sorenson, Rebecca Liu, Bonnie E Gould Rothberg, and Thorvardur R Halfdanarson
, Kunz et al. 2018 , Halfdanarson et al. 2020 ). Diagnosis and prognosis of PNETs depend on both cell morphology (degree of differentiation) and tumor grade as measured by the rate of cell proliferation (Ki-67 index and/or mitotic rate). This field
Xianhui Ruan, Jiaoyu Yi, Linfei Hu, Jingtai Zhi, Yu Zeng, Xiukun Hou, Jianfeng Huang, Pengfei Gu, Weijing Hao, Ming Gao, Yi Pan, Songfeng Wei, and Xiangqian Zheng
, including melanoma, breast cancer, colorectal cancer, ovarian cancer, prostate cancer, glioma, and non-small cell lung cancer, have found an association between tsMHC-II and a favorable prognosis ( Yazawa et al. 1999 , Bustin et al. 2001 , Soos et al
Massimo Milione, Patrick Maisonneuve, Alessio Pellegrinelli, Federica Grillo, Luca Albarello, Paola Spaggiari, Alessandro Vanoli, Giovanna Tagliabue, Eleonora Pisa, Luca Messerini, Giovanni Centonze, Frediano Inzani, Aldo Scarpa, Mauro Papotti, Marco Volante, Fausto Sessa, Nicola Fazio, Giancarlo Pruneri, Guido Rindi, Enrico Solcia, Stefano La Rosa, and Carlo Capella
demonstrates that the prognosis of MANECs from digestive system is driven mostly by the NEC component with special reference to its Ki67 proliferative index. Ki67 index of the NEC component has proven to be far superior to MC or, indeed, to any other prognostic
Yuanliang Yan, Qiuju Liang, Yuanhong Liu, Shangjun Zhou, and Zhijie Xu
, COL12A1 was found to influence the therapeutic responses toward durvalumab, an anti-PD-L1 inhibitory ( Bachelot et al. 2021 ) and predict poor prognosis in BC. Moreover, COL12A1 was highly expressed in BC tissues, estrogen receptor (ER
Maria Chiara Zatelli, Erika Maria Grossrubatscher, Elia Guadagno, Concetta Sciammarella, Antongiulio Faggiano, and Annamaria Colao
Introduction Neuroendocrine neoplasms (NENs) are heterogeneous tumors with widely different behavior and prognosis, that to date had been related mainly to the grade of neuroendocrine differentiation as well as the proliferative attitude of
Cristina Gurizzan, Manuel Zamparini, Marco Volante, Valeria Tovazzi, Vito Amoroso, Francesca Consoli, Fausto Petrelli, Salvatore Grisanti, Paolo Bossi, and Alfredo Berruti
patient prognosis is frequently favorable; however, aggressive cases have also been described, making the identification of prognostic parameters important. This study was undertaken to systematically review all ITC cases described in the literature
O Chabre, R Libé, G Assie, O Barreau, J Bertherat, X Bertagna, J-J Feige, and N Cherradi
Introduction Adrenocortical cancer is a rare malignancy that affects one to two people per million per year. Patients with adrenocortical carcinoma (ACC) generally have a poor prognosis, with a 5-year survival rate ranging from 15 to 30% ( Allolio
Masaki Shiota, Shuichi Tatarano, Toshiyuki Kamoto, Hideyasu Matsuyama, Hideki Sakai, Tsukasa Igawa, Tomomi Kamba, Naohiro Fujimoto, Yuya Sekine, Hiroko Kimura, Shintaro Narita, Naoki Terada, Yukihide Momozawa, Shusuke Akamatsu, Tomonori Habuchi, Akira Yokomizo, Seiji Naito, and Masatoshi Eto
addition to tumor features, host characteristics are considered to be an important factor affecting prognosis in ADT. Indeed, lower survival rates following ADT have been shown in Caucasians and African Americans, compared with Asians ( Fukagai et al
