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Marjory Alana Marcello, Lucas Leite Cunha, Fernando Assis Batista and Laura Sterian Ward

, endometrial cancer, colon cancer, esophageal adenocarcinoma, kidney cancer, liver cancer, pancreatic cancer, prostate cancer, thyroid cancers, leukemia, non-Hodgkin lymphoma, and myeloma are related to overweight and obesity with respect to development

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Weijun Wei, Heather Hardin and Quan-Yong Luo

Introduction Thyroid cancer is the fifth most common cancer in women in the United States and is the most commonly diagnosed cancer before the age of 30 years among women in China ( Chen et al. 2016 ). Although thyroid cancer is generally

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Carles Zafon, Joan Gil, Beatriz Pérez-González and Mireia Jordà

Introduction Thyroid cancer, the most prevalent endocrine malignancy, covers the full range of phenotypes from indolent to the worst forms of human cancer. It is categorized into differentiated thyroid cancer (DTC), poorly differentiated

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M Xing

Introduction Thyroid cancer is the most common endocrine malignancy. It can be classified histologically into follicular epithelial cell-derived papillary thyroid cancer (PTC), follicular thyroid cancer (FTC), anaplastic thyroid

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Zhenying Guo, Heather Hardin and Ricardo V Lloyd

Introduction Thyroid cancer is one of the most rapidly increasing malignancies in the USA ( Siegel et al . 2013 ). Although most well-differentiated thyroid cancers have a good prognosis, a small percentage of these tumors are associated with

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Hao Fu, Lin Cheng, Yuchen Jin and Libo Chen

thyroid carcinoma. With globally rising incidence, thyroid carcinoma has attracted much more concern than before. In theory, thyrotoxicosis with suppressed TSH should lead to a lower incidence of thyroid cancer than that observed in euthyroid patients

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Jaume Capdevila, Lara Iglesias, Irene Halperin, Ángel Segura, Javier Martínez-Trufero, Maria Ángeles Vaz, Jesús Corral, Gabriel Obiols, Enrique Grande, Juan Jose Grau and Josep Tabernero

to a more optimistic outcome for the treatment of these patients. Thyroid cancer has become one of the most fascinating models of carcinogenesis and is a particularly promising paradigm for targeted therapy. A multistep model has been proposed as a

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Rengyun Liu and Mingzhao Xing

glioblastoma ( Killela et al . 2013 , Liu et al . 2013 a ) as well as thyroid cancer ( Liu et al . 2013 b ). There are two common recurrent TERT promoter mutations in human cancer that are located at two hotspots: chr5, 1,295,228 C>T (C228T) and 1

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Xianhui Ruan, Xianle Shi, Qiman Dong, Yang Yu, Xiukun Hou, Xinhao Song, Xi Wei, Lingyi Chen and Ming Gao

Introduction Thyroid cancer is the most common cancer of endocrine system, with a rapid worldwide increase over recent decades ( Enewold et al. 2009 , Kilfoy et al. 2009 , Chen et al. 2016 ). The disease is classified into three types

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Amandine Berdelou, Livia Lamartina, Michele Klain, Sophie Leboulleux, Martin Schlumberger and on behalf of the TUTHTYREF Network

cancers, there is no evidence that their incidence changes with time. They are the main cause of thyroid cancer-related deaths, with mortality rates of 65% and 75% at 5 and 10 years after the diagnosis of the metastases ( Casara et al . 1993 , Ruegemer