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Jae Hyun Park Department of Surgery, Wonju Severance Christian Hospital, Yonsei University Wonju College of Medicine, Wonju, South Korea

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Jong Ho Yoon Department of Surgery, Wonju Severance Christian Hospital, Yonsei University Wonju College of Medicine, Wonju, South Korea

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Introduction Surgical treatment for a differentiated thyroid carcinoma (DTC) derived from follicular cells is a starting point of a multifaceted treatment approach. Even though DTC is generally non-aggressive and has good prognosis, choosing

Article Type:
Review Article
DOI:
https://doi.org/10.1530/ERC-19-0085
Volume/Issue:
Volume 26: Issue 7
Free access
Johan O Paulsson Department of Oncology-Pathology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
Department of Breast, Endocrine Tumours and Sarcoma, Karolinska University Hospital, Stockholm, Sweden

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Na Wang Department of Oncology-Pathology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden

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Jiwei Gao Department of Oncology-Pathology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden

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Adam Stenman Department of Oncology-Pathology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
Department of Breast, Endocrine Tumours and Sarcoma, Karolinska University Hospital, Stockholm, Sweden

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Jan Zedenius Department of Molecular Medicine and Surgery, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
Department of Breast, Endocrine Tumours and Sarcoma, Karolinska University Hospital, Stockholm, Sweden

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Ninni Mu Department of Oncology-Pathology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden

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Weng-Onn Lui Department of Oncology-Pathology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden

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Catharina Larsson Department of Oncology-Pathology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden

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C Christofer Juhlin Department of Oncology-Pathology, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
Department of Pathology and Cytology, Karolinska University Hospital, Stockholm, Sweden

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the last few decades, especially since the beginning of the 1990s, but the mortality rate has remained relatively stable ( Kitahara & Sosa 2016 ). The increase is mainly attributable to the increasing incidence of papillary thyroid carcinoma (PTC), but

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-19-0446
Volume/Issue:
Volume 27: Issue 5
Open access
Kyoungjune Pak Department of Nuclear Medicine, Department of Internal Medicine, Medical Research Institute
Department of Nuclear Medicine, Department of Internal Medicine, Medical Research Institute

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Seong-Jang Kim Department of Nuclear Medicine, Department of Internal Medicine, Medical Research Institute
Department of Nuclear Medicine, Department of Internal Medicine, Medical Research Institute

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In Joo Kim Department of Nuclear Medicine, Department of Internal Medicine, Medical Research Institute
Department of Nuclear Medicine, Department of Internal Medicine, Medical Research Institute

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Bo Hyun Kim Department of Nuclear Medicine, Department of Internal Medicine, Medical Research Institute
Department of Nuclear Medicine, Department of Internal Medicine, Medical Research Institute

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Sang Soo Kim Department of Nuclear Medicine, Department of Internal Medicine, Medical Research Institute
Department of Nuclear Medicine, Department of Internal Medicine, Medical Research Institute

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Yun Kyung Jeon Department of Nuclear Medicine, Department of Internal Medicine, Medical Research Institute
Department of Nuclear Medicine, Department of Internal Medicine, Medical Research Institute

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the procedure of choice and is the most accurate and cost-effective method of diagnosing thyroid carcinoma. Globally, the incidence of thyroid cancer has been increasing sharply since the mid-1990s, and it is the cancer with the fastest increasing

Article Type:
Review Article
DOI:
https://doi.org/10.1530/ERC-13-0088
Volume/Issue:
Volume 20: Issue 4
Free access
Kirk Jensen Department of Pediatrics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA

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Athanasios Bikas Department of Internal Medicine, Georgetown University Hospital MedStar, Washington Hospital Center Internal Medicine Residency Program, Washington, District of Columbia, USA

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Aneeta Patel Department of Pediatrics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA

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Yevgeniya Kushchayeva National Institutes of Health, NIDDK, Bethesda, Maryland, USA

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John Costello Department of Pediatrics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA

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Dennis McDaniel Uniformed Services University of the Health Sciences, Biomedical Instrumentation Center, Bethesda, Maryland, USA

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Kenneth Burman MedStar Washington Hospital Center, Endocrinology, Washington, District of Columbia, USA

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Vasyl Vasko Department of Pediatrics, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA

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-derived thyroid carcinomas ( Xu et al . 2016 ). Both recurrences and death from PTC can occur more than 30 years after being treated, and development of recurrent disease significantly worsens prognosis ( Grogan et al . 2013 ). In patients stratified according

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-16-0568
Volume/Issue:
Volume 24: Issue 3
Free access
Fadi Nabhan Division of Endocrinology, Diabetes and Metabolism, The Ohio State University College of Medicine, Wexner Medical Center, Arthur G. James Comprehensive Cancer Center, Columbus, Ohio, USA

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Matthew D Ringel Division of Endocrinology, Diabetes and Metabolism, The Ohio State University College of Medicine, Wexner Medical Center, Arthur G. James Comprehensive Cancer Center, Columbus, Ohio, USA

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nodules, it was not part of the features that make a nodule high-risk thyroid lesion ( Table 2 ). b Adapted with permission from Haddad RI, et al. , NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) for Thyroid Carcinoma Version 1

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Review Article
DOI:
https://doi.org/10.1530/ERC-16-0432
Volume/Issue:
Volume 24: Issue 2
Free access
Ebtesam Qasem Department of Molecular Oncology, Department of Pathology and Laboratory Medicine, Department of Medicine, Division of Endocrinology and Metabolism, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

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Avaniyapuram Kannan Murugan Department of Molecular Oncology, Department of Pathology and Laboratory Medicine, Department of Medicine, Division of Endocrinology and Metabolism, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

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Hindi Al-Hindi Department of Molecular Oncology, Department of Pathology and Laboratory Medicine, Department of Medicine, Division of Endocrinology and Metabolism, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

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Mingzhao Xing Department of Molecular Oncology, Department of Pathology and Laboratory Medicine, Department of Medicine, Division of Endocrinology and Metabolism, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

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Mai Almohanna Department of Molecular Oncology, Department of Pathology and Laboratory Medicine, Department of Medicine, Division of Endocrinology and Metabolism, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

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Meshael Alswailem Department of Molecular Oncology, Department of Pathology and Laboratory Medicine, Department of Medicine, Division of Endocrinology and Metabolism, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

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Ali S Alzahrani Department of Molecular Oncology, Department of Pathology and Laboratory Medicine, Department of Medicine, Division of Endocrinology and Metabolism, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia
Department of Molecular Oncology, Department of Pathology and Laboratory Medicine, Department of Medicine, Division of Endocrinology and Metabolism, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia

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Aksoy BA Ally A Arachchi H Asa SL Auman JT Balasundaram M Balu S Baylin SB 2014 Integrated genomic characterization of papillary thyroid carcinoma . Cell 159 676 – 690 . ( doi:10.1016/j.cell.2014.09.050 ). Antonello ZA

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-15-0396
Volume/Issue:
Volume 22: Issue 6
Free access
Monia Zidane INSERM, Centre for Research in Epidemiology and Population Health (CESP), U1018, Radiation Epidemiology Group, Villejuif, France
Université Paris-Sud Orsay, Île-de-France, France
Gustave Roussy, Villejuif, France

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Jean-Baptiste Cazier Institute of Cancer and Genomic Sciences, Centre for Computational Biology, University of Birmingham, Birmingham, UK

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Sylvie Chevillard CEA, Direction de la Recherche Fondamentale, Institut de Biologie François Jacob, iRCM, SREIT, Laboratoire de Cancérologie Expérimentale (LCE), Université Paris-Saclay, Fontenay-aux-Roses, France

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Catherine Ory CEA, Direction de la Recherche Fondamentale, Institut de Biologie François Jacob, iRCM, SREIT, Laboratoire de Cancérologie Expérimentale (LCE), Université Paris-Saclay, Fontenay-aux-Roses, France

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Martin Schlumberger Université Paris-Sud Orsay, Île-de-France, France
Gustave Roussy, Villejuif, France
UMR 8200 CNRS, Villejuif, France

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Corinne Dupuy Université Paris-Sud Orsay, Île-de-France, France
Gustave Roussy, Villejuif, France
UMR 8200 CNRS, Villejuif, France

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Jean-François Deleuze Centre National de Recherche en Génomique Humaine, CEA, Evry, France

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Anne Boland Centre National de Recherche en Génomique Humaine, CEA, Evry, France

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Nadia Haddy INSERM, Centre for Research in Epidemiology and Population Health (CESP), U1018, Radiation Epidemiology Group, Villejuif, France
Université Paris-Sud Orsay, Île-de-France, France
Gustave Roussy, Villejuif, France

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Fabienne Lesueur Institut Curie, Paris, France
PSL Research University, Paris, France
INSERM, U900, Paris, France
Mines Paris Tech, Fontainebleau, France

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Florent de Vathaire INSERM, Centre for Research in Epidemiology and Population Health (CESP), U1018, Radiation Epidemiology Group, Villejuif, France
Université Paris-Sud Orsay, Île-de-France, France
Gustave Roussy, Villejuif, France

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. Papillary thyroid carcinoma (PTC) is the most frequent histology type of DTC, representing almost 80% of DTC cases. PTC is also the most frequent type among familial DTC, which represents between 3 and 9% of new DTC cases diagnosed each year ( Vriens et al

Article Type:
Review Article
DOI:
https://doi.org/10.1530/ERC-19-0321
Volume/Issue:
Volume 26: Issue 10
Free access
Astrid Kehlen
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Monique Haegele
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Katja Menge
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Kathrin Gans
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Uta-Dorothee Immel Probiodrug AG, Martin Luther University of Halle‐Wittenberg, University of Manitoba, Weinbergweg 22, D-06120 Halle, Saale, Germany

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Cuong Hoang-Vu Probiodrug AG, Martin Luther University of Halle‐Wittenberg, University of Manitoba, Weinbergweg 22, D-06120 Halle, Saale, Germany

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Thomas Klonisch Probiodrug AG, Martin Luther University of Halle‐Wittenberg, University of Manitoba, Weinbergweg 22, D-06120 Halle, Saale, Germany

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Hans-Ulrich Demuth
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al . 2011 ). In papillary thyroid carcinoma (PTC), CCL2 is correlated with lymph node metastasis and tumor recurrence ( Tanaka et al . 2009 ). Interestingly, the oncogenic fusion protein RET/PTC expressed in PTC activates the transcription factor NF

Article Type:
Research Article
DOI:
https://doi.org/10.1530/ERC-12-0053
Volume/Issue:
Volume 20: Issue 1
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P Pallante
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R Visone
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M Ferracin
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A Ferraro
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M T Berlingieri
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G Troncone
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G Chiappetta
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C G Liu
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M Santoro
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M Negrini
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C M Croce
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A Fusco
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different degrees of malignancy from benign adenomas, which are not invasive and very well differentiated, to the undifferentiated anaplastic thyroid carcinomas, which are very aggressive and always fatal. Papillary and follicular carcinomas, the most common

Article Type:
Research Article
DOI:
https://doi.org/10.1677/erc.1.01209
Volume/Issue:
Volume 13: Issue 2
Free access
Alfred King-yin Lam School of Medicine, Griffith University, Gold Coast, Australia

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Introduction Squamous cell carcinoma is a rare tumour of the thyroid gland. In the second edition of the World Health Organization (WHO) Histological Typing of Thyroid Tumours published in 1988, squamous cell carcinoma of the thyroid gland was

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Review Article
DOI:
https://doi.org/10.1530/ERC-20-0045
Volume/Issue:
Volume 27: Issue 6
Free access