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The journal and typesetter apologise for an error that occurred in the paper by Lassalle et al. in the October 2011 issue of Endocrine-Related Cancer 18 579–594 entitled ‘Can the microRNA signature distinguish between thyroid tumors of uncertain malignant potential and other well-differentiated tumors of the thyroid gland?'. The error relates to misaligned labelling on the right-hand side of Figure 1 as printed on page 585. The figure appears in full below:

Figure 1
Figure 1

Heat map of 84 differentially expressed miRNAs analyzed for 42 patients. The cutoff values equal to 7.5 for the log2 (signal), ±0.7 for the log2(ratio), and 0.01 for the adjusted P value were used. Each column corresponds to one patient: five C-PTC with wildtype BRAF, six C-PTC with mutated BRAF, five FV-PTC, seven adenomas, six FTC, six WDT-UMP, and seven FT-UMP were analyzed. Each line corresponds to one of the 84 miRNAs found differentially expressed between normal and pathological tissues, or differing between at least two experimental groups. The false color image represents the log2(ratio) between lesion and control biopsies. The log2(ratio) was measured between normal and pathological RNA extracted from the same patient. Control tissue was taken at a large distance from the lesion in order to minimize the risk of contamination with tumor tissue. Distances were measured according to Spearman. Clustering was performed using a complete method. wtC-PTC, wild-type classical papillary thyroid carcinoma (C-PTC non-mutated for BRAF V600); mutC-PTC, mutated classical papillary papillary thyroid carcinoma (C-PTC mutated for BRAF V600). FV-PTC, follicular variant of papillary thyroid carcinoma; FTC, follicular thyroid carcinoma; FTA, follicular thyroid adenoma; WDT-UMP, well-differentiated tumors of uncertain malignant potential; FT-UMP, follicular tumor of uncertain malignant potential.

Citation: Endocrine-Related Cancer 18, 6; 10.1530/ERC-10-0283e

 

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  • Heat map of 84 differentially expressed miRNAs analyzed for 42 patients. The cutoff values equal to 7.5 for the log2 (signal), ±0.7 for the log2(ratio), and 0.01 for the adjusted P value were used. Each column corresponds to one patient: five C-PTC with wildtype BRAF, six C-PTC with mutated BRAF, five FV-PTC, seven adenomas, six FTC, six WDT-UMP, and seven FT-UMP were analyzed. Each line corresponds to one of the 84 miRNAs found differentially expressed between normal and pathological tissues, or differing between at least two experimental groups. The false color image represents the log2(ratio) between lesion and control biopsies. The log2(ratio) was measured between normal and pathological RNA extracted from the same patient. Control tissue was taken at a large distance from the lesion in order to minimize the risk of contamination with tumor tissue. Distances were measured according to Spearman. Clustering was performed using a complete method. wtC-PTC, wild-type classical papillary thyroid carcinoma (C-PTC non-mutated for BRAF V600); mutC-PTC, mutated classical papillary papillary thyroid carcinoma (C-PTC mutated for BRAF V600). FV-PTC, follicular variant of papillary thyroid carcinoma; FTC, follicular thyroid carcinoma; FTA, follicular thyroid adenoma; WDT-UMP, well-differentiated tumors of uncertain malignant potential; FT-UMP, follicular tumor of uncertain malignant potential.